ES361189A1 - Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos racemicos u opticamente acti-vos. - Google Patents

Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos racemicos u opticamente acti-vos.

Info

Publication number
ES361189A1
ES361189A1 ES361189A ES361189A ES361189A1 ES 361189 A1 ES361189 A1 ES 361189A1 ES 361189 A ES361189 A ES 361189A ES 361189 A ES361189 A ES 361189A ES 361189 A1 ES361189 A1 ES 361189A1
Authority
ES
Spain
Prior art keywords
propanes
alkylamino
phenoxy
hydroxy
adrenolytics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES361189A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES361189A1 publication Critical patent/ES361189A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES361189A 1967-12-13 1968-12-07 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos racemicos u opticamente acti-vos. Expired ES361189A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (de) 1967-12-13 1967-12-13 i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ES361189A1 true ES361189A1 (es) 1970-08-16

Family

ID=5684274

Family Applications (11)

Application Number Title Priority Date Filing Date
ES361189A Expired ES361189A1 (es) 1967-12-13 1968-12-07 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-alcohilaminopropanos racemicos u opticamente acti-vos.
ES375449A Expired ES375449A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375450A Expired ES375450A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375447A Expired ES375447A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375445A Expired ES375445A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES375448A Expired ES375448A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375444A Expired ES375444A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375446A Expired ES375446A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375451A Expired ES375451A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375453A Expired ES375453A1 (es) 1967-12-13 1970-01-15 Procedimiento para la produccion de preparados farmaceuti- cos a base de 1-fenoxi-2-hidroxi-3-alcohilaminopropanos.
ES375452A Expired ES375452A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaainopropanos racemicos u opticamente ac-tivos.

Family Applications After (10)

Application Number Title Priority Date Filing Date
ES375449A Expired ES375449A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375450A Expired ES375450A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375447A Expired ES375447A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375445A Expired ES375445A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES375448A Expired ES375448A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375444A Expired ES375444A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375446A Expired ES375446A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375451A Expired ES375451A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos i-fenoxi-2-hi- droxi-3 - alcohilaminopropanos racemicos u opticamente acti-vos.
ES375453A Expired ES375453A1 (es) 1967-12-13 1970-01-15 Procedimiento para la produccion de preparados farmaceuti- cos a base de 1-fenoxi-2-hidroxi-3-alcohilaminopropanos.
ES375452A Expired ES375452A1 (es) 1967-12-13 1970-01-15 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaainopropanos racemicos u opticamente ac-tivos.

Country Status (21)

Country Link
US (1) US3872147A (de)
JP (1) JPS5220457B1 (de)
AT (13) AT292670B (de)
BE (1) BE725490A (de)
BG (9) BG17298A3 (de)
BR (1) BR6804840D0 (de)
CA (1) CA954528A (de)
CH (2) CH532015A (de)
DE (1) DE1643262C3 (de)
DK (1) DK131029B (de)
ES (11) ES361189A1 (de)
FI (1) FI49497C (de)
FR (2) FR1596100A (de)
GB (1) GB1260866A (de)
HU (1) HU162734B (de)
IE (1) IE32758B1 (de)
IL (1) IL31266A (de)
NL (3) NL146709B (de)
PH (1) PH9266A (de)
SE (1) SE367396B (de)
YU (12) YU33949B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3062216D1 (en) * 1979-09-06 1983-04-07 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (de) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
ATE45724T1 (de) * 1985-12-24 1989-09-15 Merck & Co Inc Okuloselektive betablocker.
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
YU237474A (en) 1977-12-31
ES375447A1 (es) 1972-05-01
YU237874A (en) 1977-12-31
NL7501794A (nl) 1975-05-30
YU237574A (en) 1978-02-28
YU33774B (en) 1978-05-15
ES375452A1 (es) 1972-05-16
ES375445A1 (es) 1972-05-16
YU33856B (en) 1978-06-30
YU237774A (en) 1978-02-28
AT292681B (de) 1971-08-15
YU238074A (en) 1977-12-31
ES375451A1 (es) 1972-05-01
YU237974A (en) 1977-12-31
YU33852B (en) 1978-06-30
DK131029C (de) 1975-10-06
NL7501792A (nl) 1975-05-30
FR8328M (de) 1970-12-07
FR1596100A (de) 1970-06-15
FI49497B (de) 1975-04-01
ES375453A1 (es) 1972-05-16
BG16445A3 (bg) 1972-11-20
FI49497C (fi) 1975-07-10
BG16330A3 (bg) 1972-08-20
YU33948B (en) 1978-09-08
YU33853B (en) 1978-06-30
YU33946B (en) 1978-09-08
YU294968A (en) 1978-02-28
US3872147A (en) 1975-03-18
CH532015A (de) 1972-12-31
AT298463B (de) 1972-05-10
IL31266A (en) 1974-09-10
NL151354B (nl) 1976-11-15
YU238274A (en) 1977-12-31
ES375450A1 (es) 1972-05-01
DE1643262B2 (de) 1974-11-07
BG16331A3 (bg) 1972-08-20
YU33851B (en) 1978-06-30
AT298459B (de) 1972-05-10
AT294799B (de) 1971-12-10
AT292677B (de) 1971-09-10
NL6817768A (de) 1969-06-17
DE1643262C3 (de) 1975-06-26
AT292679B (de) 1971-09-10
BG17298A3 (de) 1973-07-25
AT292678B (de) 1971-09-10
YU237674A (en) 1977-10-31
BG17297A3 (de) 1973-07-25
ES375444A1 (es) 1972-05-01
NL146709B (nl) 1975-08-15
YU33854B (en) 1978-06-30
GB1260866A (en) 1972-01-19
ES375449A1 (es) 1972-05-01
ES375448A1 (es) 1972-05-01
SE367396B (de) 1974-05-27
ES375446A1 (es) 1972-05-01
YU33773B (en) 1978-05-15
YU33947B (en) 1978-09-08
DK131029B (da) 1975-05-20
DE1643262A1 (de) 1972-04-20
IL31266A0 (en) 1969-02-27
AT292670B (de) 1971-09-10
YU238474A (en) 1978-02-28
BE725490A (de) 1969-06-13
YU33949B (en) 1978-09-08
IE32758L (en) 1969-06-13
AT292673B (de) 1971-09-10
HU162734B (de) 1973-04-28
AT292680B (de) 1971-09-10
BR6804840D0 (pt) 1973-03-08
BG19135A3 (de) 1975-04-30
BG16332A3 (bg) 1972-08-20
PH9266A (en) 1975-07-30
BG16444A3 (bg) 1972-11-20
YU238374A (en) 1977-12-31
AT292676B (de) 1971-09-10
AT292675B (de) 1971-09-10
BG16329A3 (bg) 1972-08-20
CH556816A (de) 1974-12-13
YU33855B (en) 1978-06-30
CA954528A (en) 1974-09-10
JPS5220457B1 (de) 1977-06-03
AT292674B (de) 1971-09-10
IE32758B1 (en) 1973-11-28
YU238174A (en) 1977-10-31

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