BG19135A3 - Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани - Google Patents

Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани

Info

Publication number
BG19135A3
BG19135A3 BG012146A BG1214668A BG19135A3 BG 19135 A3 BG19135 A3 BG 19135A3 BG 012146 A BG012146 A BG 012146A BG 1214668 A BG1214668 A BG 1214668A BG 19135 A3 BG19135 A3 BG 19135A3
Authority
BG
Bulgaria
Prior art keywords
alkylaminopropanes
phenoxy
hydroxy
obtaining new
obtaining
Prior art date
Application number
BG012146A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Koeppe
Werner Kummer
Helmut Staehle
Karl Zeile
Albrecht Engelhardt
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG19135A3 publication Critical patent/BG19135A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG012146A 1967-12-13 1968-12-13 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани BG19135A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (de) 1967-12-13 1967-12-13 i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
BG19135A3 true BG19135A3 (bg) 1975-04-30

Family

ID=5684274

Family Applications (9)

Application Number Title Priority Date Filing Date
BG012150A BG17298A3 (bg) 1967-12-13 1968-04-03 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG012149A BG17297A3 (bg) 1967-12-13 1968-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG011231A BG16329A3 (bg) 1967-12-13 1968-12-13 Метод за получаване на нови1-фенокси-2-хидрокси-3- алкиламинопропани
BG012146A BG19135A3 (bg) 1967-12-13 1968-12-13 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG012143A BG16330A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG012144A BG16444A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3- алкиламинопропани
BG012148A BG16332A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси- -2-хидрокиси-3-алкиламинопропани
BG012147A BG16331A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси- -2-хидрокиси-3-алкиламинопропани
BG012145A BG16445A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2- хидрокси-3-алкиламинопропани

Family Applications Before (3)

Application Number Title Priority Date Filing Date
BG012150A BG17298A3 (bg) 1967-12-13 1968-04-03 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG012149A BG17297A3 (bg) 1967-12-13 1968-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG011231A BG16329A3 (bg) 1967-12-13 1968-12-13 Метод за получаване на нови1-фенокси-2-хидрокси-3- алкиламинопропани

Family Applications After (5)

Application Number Title Priority Date Filing Date
BG012143A BG16330A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3-алкиламинопропани
BG012144A BG16444A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2-хидрокси-3- алкиламинопропани
BG012148A BG16332A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси- -2-хидрокиси-3-алкиламинопропани
BG012147A BG16331A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси- -2-хидрокиси-3-алкиламинопропани
BG012145A BG16445A3 (bg) 1967-12-13 1969-04-30 Метод за получаване на нови 1-фенокси-2- хидрокси-3-алкиламинопропани

Country Status (21)

Country Link
US (1) US3872147A (de)
JP (1) JPS5220457B1 (de)
AT (13) AT292673B (de)
BE (1) BE725490A (de)
BG (9) BG17298A3 (de)
BR (1) BR6804840D0 (de)
CA (1) CA954528A (de)
CH (2) CH556816A (de)
DE (1) DE1643262C3 (de)
DK (1) DK131029B (de)
ES (11) ES361189A1 (de)
FI (1) FI49497C (de)
FR (2) FR1596100A (de)
GB (1) GB1260866A (de)
HU (1) HU162734B (de)
IE (1) IE32758B1 (de)
IL (1) IL31266A (de)
NL (3) NL146709B (de)
PH (1) PH9266A (de)
SE (1) SE367396B (de)
YU (12) YU33949B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
EP0025331B1 (de) * 1979-09-06 1983-03-02 Beecham Group Plc Zimtsäurederivate, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (de) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
ATE45724T1 (de) * 1985-12-24 1989-09-15 Merck & Co Inc Okuloselektive betablocker.
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
YU237974A (en) 1977-12-31
ES375445A1 (es) 1972-05-16
DE1643262B2 (de) 1974-11-07
NL146709B (nl) 1975-08-15
FI49497C (fi) 1975-07-10
YU33773B (en) 1978-05-15
NL6817768A (de) 1969-06-17
ES375444A1 (es) 1972-05-01
ES375450A1 (es) 1972-05-01
YU33856B (en) 1978-06-30
YU33851B (en) 1978-06-30
JPS5220457B1 (de) 1977-06-03
ES375448A1 (es) 1972-05-01
YU238074A (en) 1977-12-31
FR8328M (de) 1970-12-07
YU294968A (en) 1978-02-28
YU237874A (en) 1977-12-31
ES375452A1 (es) 1972-05-16
YU33855B (en) 1978-06-30
YU33949B (en) 1978-09-08
AT294799B (de) 1971-12-10
DK131029C (de) 1975-10-06
YU33948B (en) 1978-09-08
ES375451A1 (es) 1972-05-01
BG16331A3 (bg) 1972-08-20
AT292676B (de) 1971-09-10
AT292680B (de) 1971-09-10
BE725490A (de) 1969-06-13
YU33853B (en) 1978-06-30
AT292674B (de) 1971-09-10
BG16330A3 (bg) 1972-08-20
DK131029B (da) 1975-05-20
BG17298A3 (bg) 1973-07-25
BG16332A3 (bg) 1972-08-20
AT292670B (de) 1971-09-10
NL7501794A (nl) 1975-05-30
PH9266A (en) 1975-07-30
DE1643262A1 (de) 1972-04-20
AT292675B (de) 1971-09-10
ES361189A1 (es) 1970-08-16
YU237574A (en) 1978-02-28
IE32758L (en) 1969-06-13
YU238474A (en) 1978-02-28
SE367396B (de) 1974-05-27
YU237774A (en) 1978-02-28
US3872147A (en) 1975-03-18
IL31266A (en) 1974-09-10
AT292678B (de) 1971-09-10
AT292673B (de) 1971-09-10
DE1643262C3 (de) 1975-06-26
YU237674A (en) 1977-10-31
YU238374A (en) 1977-12-31
BR6804840D0 (pt) 1973-03-08
YU33854B (en) 1978-06-30
YU237474A (en) 1977-12-31
ES375447A1 (es) 1972-05-01
BG16329A3 (bg) 1972-08-20
CH556816A (de) 1974-12-13
ES375453A1 (es) 1972-05-16
IL31266A0 (en) 1969-02-27
GB1260866A (en) 1972-01-19
AT298459B (de) 1972-05-10
YU33774B (en) 1978-05-15
HU162734B (de) 1973-04-28
FR1596100A (de) 1970-06-15
NL151354B (nl) 1976-11-15
AT292679B (de) 1971-09-10
ES375449A1 (es) 1972-05-01
YU33947B (en) 1978-09-08
AT292681B (de) 1971-08-15
FI49497B (de) 1975-04-01
ES375446A1 (es) 1972-05-01
BG16444A3 (bg) 1972-11-20
NL7501792A (nl) 1975-05-30
YU238274A (en) 1977-12-31
YU33852B (en) 1978-06-30
YU238174A (en) 1977-10-31
AT298463B (de) 1972-05-10
CA954528A (en) 1974-09-10
AT292677B (de) 1971-09-10
BG17297A3 (bg) 1973-07-25
BG16445A3 (bg) 1972-11-20
CH532015A (de) 1972-12-31
YU33946B (en) 1978-09-08
IE32758B1 (en) 1973-11-28

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