YU33947B - Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes - Google Patents

Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes

Info

Publication number
YU33947B
YU33947B YU2377/74A YU237774A YU33947B YU 33947 B YU33947 B YU 33947B YU 2377/74 A YU2377/74 A YU 2377/74A YU 237774 A YU237774 A YU 237774A YU 33947 B YU33947 B YU 33947B
Authority
YU
Yugoslavia
Prior art keywords
2hydroxy
propanes
alkylamino
phenoxy
preparing novel
Prior art date
Application number
YU2377/74A
Other languages
English (en)
Other versions
YU237774A (en
Inventor
Koeppe Herbert
Herbert Koeppe
Kummer Werner
Werner Kummer
Staehle Helmut
Helmut Staehle
Zeile Karl
Karl Zeile
Engelhardt Albrecht
Albrecht Engelhardt
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of YU237774A publication Critical patent/YU237774A/xx
Publication of YU33947B publication Critical patent/YU33947B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
YU2377/74A 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes YU33947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (de) 1967-12-13 1967-12-13 i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
YU237774A YU237774A (en) 1978-02-28
YU33947B true YU33947B (en) 1978-09-08

Family

ID=5684274

Family Applications (12)

Application Number Title Priority Date Filing Date
YU2949/68A YU33949B (en) 1967-12-13 1968-12-12 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2378/74A YU33852B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2384/74A YU33948B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2376/74A YU33773B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2383/74A YU33856B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2375/74A YU33946B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2380/74A YU33854B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2379/74A YU33853B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2377/74A YU33947B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2382/74A YU33855B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2381/74A YU33774B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2374/74A YU33851B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes

Family Applications Before (8)

Application Number Title Priority Date Filing Date
YU2949/68A YU33949B (en) 1967-12-13 1968-12-12 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2378/74A YU33852B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2384/74A YU33948B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2376/74A YU33773B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2383/74A YU33856B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2375/74A YU33946B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2380/74A YU33854B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2379/74A YU33853B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes

Family Applications After (3)

Application Number Title Priority Date Filing Date
YU2382/74A YU33855B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2381/74A YU33774B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2374/74A YU33851B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes

Country Status (21)

Country Link
US (1) US3872147A (xx)
JP (1) JPS5220457B1 (xx)
AT (13) AT292670B (xx)
BE (1) BE725490A (xx)
BG (9) BG17298A3 (xx)
BR (1) BR6804840D0 (xx)
CA (1) CA954528A (xx)
CH (2) CH532015A (xx)
DE (1) DE1643262C3 (xx)
DK (1) DK131029B (xx)
ES (11) ES361189A1 (xx)
FI (1) FI49497C (xx)
FR (2) FR1596100A (xx)
GB (1) GB1260866A (xx)
HU (1) HU162734B (xx)
IE (1) IE32758B1 (xx)
IL (1) IL31266A (xx)
NL (3) NL146709B (xx)
PH (1) PH9266A (xx)
SE (1) SE367396B (xx)
YU (12) YU33949B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3062216D1 (en) * 1979-09-06 1983-04-07 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (de) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
ATE45724T1 (de) * 1985-12-24 1989-09-15 Merck & Co Inc Okuloselektive betablocker.
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
YU237474A (en) 1977-12-31
ES375447A1 (es) 1972-05-01
YU237874A (en) 1977-12-31
NL7501794A (nl) 1975-05-30
YU237574A (en) 1978-02-28
YU33774B (en) 1978-05-15
ES375452A1 (es) 1972-05-16
ES375445A1 (es) 1972-05-16
YU33856B (en) 1978-06-30
YU237774A (en) 1978-02-28
AT292681B (de) 1971-08-15
YU238074A (en) 1977-12-31
ES375451A1 (es) 1972-05-01
YU237974A (en) 1977-12-31
YU33852B (en) 1978-06-30
DK131029C (xx) 1975-10-06
NL7501792A (nl) 1975-05-30
FR8328M (xx) 1970-12-07
FR1596100A (xx) 1970-06-15
FI49497B (xx) 1975-04-01
ES375453A1 (es) 1972-05-16
BG16445A3 (bg) 1972-11-20
FI49497C (fi) 1975-07-10
BG16330A3 (bg) 1972-08-20
YU33948B (en) 1978-09-08
YU33853B (en) 1978-06-30
YU33946B (en) 1978-09-08
YU294968A (en) 1978-02-28
US3872147A (en) 1975-03-18
CH532015A (de) 1972-12-31
AT298463B (de) 1972-05-10
IL31266A (en) 1974-09-10
NL151354B (nl) 1976-11-15
YU238274A (en) 1977-12-31
ES375450A1 (es) 1972-05-01
DE1643262B2 (de) 1974-11-07
BG16331A3 (bg) 1972-08-20
YU33851B (en) 1978-06-30
AT298459B (de) 1972-05-10
AT294799B (de) 1971-12-10
AT292677B (de) 1971-09-10
NL6817768A (xx) 1969-06-17
DE1643262C3 (de) 1975-06-26
AT292679B (de) 1971-09-10
BG17298A3 (xx) 1973-07-25
AT292678B (de) 1971-09-10
YU237674A (en) 1977-10-31
BG17297A3 (xx) 1973-07-25
ES375444A1 (es) 1972-05-01
NL146709B (nl) 1975-08-15
YU33854B (en) 1978-06-30
GB1260866A (en) 1972-01-19
ES375449A1 (es) 1972-05-01
ES375448A1 (es) 1972-05-01
SE367396B (xx) 1974-05-27
ES375446A1 (es) 1972-05-01
YU33773B (en) 1978-05-15
DK131029B (da) 1975-05-20
DE1643262A1 (de) 1972-04-20
IL31266A0 (en) 1969-02-27
ES361189A1 (es) 1970-08-16
AT292670B (de) 1971-09-10
YU238474A (en) 1978-02-28
BE725490A (xx) 1969-06-13
YU33949B (en) 1978-09-08
IE32758L (en) 1969-06-13
AT292673B (de) 1971-09-10
HU162734B (xx) 1973-04-28
AT292680B (de) 1971-09-10
BR6804840D0 (pt) 1973-03-08
BG19135A3 (xx) 1975-04-30
BG16332A3 (bg) 1972-08-20
PH9266A (en) 1975-07-30
BG16444A3 (bg) 1972-11-20
YU238374A (en) 1977-12-31
AT292676B (de) 1971-09-10
AT292675B (de) 1971-09-10
BG16329A3 (bg) 1972-08-20
CH556816A (de) 1974-12-13
YU33855B (en) 1978-06-30
CA954528A (en) 1974-09-10
JPS5220457B1 (xx) 1977-06-03
AT292674B (de) 1971-09-10
IE32758B1 (en) 1973-11-28
YU238174A (en) 1977-10-31

Similar Documents

Publication Publication Date Title
YU35093B (en) Process for preparing bis-stilbene compounds
YU237774A (en) Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamin-propanes
YU34138B (en) Process for preparing novel halo-pregnanedienes
YU34283B (en) Process for preparing substituted acetylguanidines
YU34400B (en) Process for preparing bis-thioureido-benzenes
YU240274A (en) Process for obtaining benzodipyran
YU199068A (en) Process for preparing novel 2-nitro-2furyl-2-isoxazoline derivatives
YU33775B (en) Process for preparing novel substituted 1-phenoxy-2-hydroxy-3-tert.-butylamino-propanes
YU34043B (en) Process for preparing novel 3-amino-acylamino-thiophens
YU163373A (en) Process for preparing ethyl-aubstituted 1-phenoxy-2-hydroxy-3-alkylaminopropanes
YU206267A (en) Process for preparing pyroquinole compounds
YU257568A (en) Process for preparing novel 7-methyl-steroids
YU34109B (en) Process for preparing acrylophenones
YU34085B (en) Process for preparing n-tritylimidazoles
YU30968A (en) Process for preparing alfa-6-deoxytetracycline
YU33926B (en) Process for preparing substituted 2-aminobenzimidazoles
YU34127B (en) Process for preparing novel pyrimidi eccompounds
YU277079A (en) Process for obtaining 2-akoxy-5-chlorosulfonyl-nitrobenzene
YU277179A (en) Process for obtaining 2-alkoxy-5-chlorosulfonyl-nitrobenzene