YU238174A - Process for preparing novel 1-phenoxy-2hydroxy3-alkylamino-propanes - Google Patents

Process for preparing novel 1-phenoxy-2hydroxy3-alkylamino-propanes

Info

Publication number
YU238174A
YU238174A YU02381/74A YU238174A YU238174A YU 238174 A YU238174 A YU 238174A YU 02381/74 A YU02381/74 A YU 02381/74A YU 238174 A YU238174 A YU 238174A YU 238174 A YU238174 A YU 238174A
Authority
YU
Yugoslavia
Prior art keywords
2hydroxy3
propanes
alkylamino
phenoxy
preparing novel
Prior art date
Application number
YU02381/74A
Other versions
YU33774B (en
Inventor
Herbert Koeppe
Koeppe Herbert
Werner Kummer
Kummer Werner
Helmut Staehle
Staehle Helmut
Karl Zeile
Zeile Karl
Albrecht Engelhardt
Engelhardt Albrecht
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of YU238174A publication Critical patent/YU238174A/en
Publication of YU33774B publication Critical patent/YU33774B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
YU2381/74A 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2) YU33774B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (en) 1967-12-13 1967-12-13 i-Phenoxy ^ -hydroxy-S-alklyaminopropane, process for their preparation and medicaments containing these compounds

Publications (2)

Publication Number Publication Date
YU238174A true YU238174A (en) 1977-10-31
YU33774B YU33774B (en) 1978-05-15

Family

ID=5684274

Family Applications (12)

Application Number Title Priority Date Filing Date
YU2949/68A YU33949B (en) 1967-12-13 1968-12-12 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2376/74A YU33773B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2380/74A YU33854B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2377/74A YU33947B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2374/74A YU33851B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2381/74A YU33774B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2382/74A YU33855B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2379/74A YU33853B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2383/74A YU33856B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2384/74A YU33948B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2378/74A YU33852B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2375/74A YU33946B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes

Family Applications Before (5)

Application Number Title Priority Date Filing Date
YU2949/68A YU33949B (en) 1967-12-13 1968-12-12 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2376/74A YU33773B (en) 1967-12-13 1974-09-03 Process for preparing novel, mixed substituted 1-phenoxy-3-alkylamino-propanols-(2)
YU2380/74A YU33854B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2377/74A YU33947B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2374/74A YU33851B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes

Family Applications After (6)

Application Number Title Priority Date Filing Date
YU2382/74A YU33855B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2379/74A YU33853B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2383/74A YU33856B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2384/74A YU33948B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes
YU2378/74A YU33852B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino propanes
YU2375/74A YU33946B (en) 1967-12-13 1974-09-03 Process for preparing novel 1-phenoxy-2hydroxy-3-alkylamino-propanes

Country Status (21)

Country Link
US (1) US3872147A (en)
JP (1) JPS5220457B1 (en)
AT (13) AT292679B (en)
BE (1) BE725490A (en)
BG (9) BG17298A3 (en)
BR (1) BR6804840D0 (en)
CA (1) CA954528A (en)
CH (2) CH532015A (en)
DE (1) DE1643262C3 (en)
DK (1) DK131029B (en)
ES (11) ES361189A1 (en)
FI (1) FI49497C (en)
FR (2) FR1596100A (en)
GB (1) GB1260866A (en)
HU (1) HU162734B (en)
IE (1) IE32758B1 (en)
IL (1) IL31266A (en)
NL (3) NL146709B (en)
PH (1) PH9266A (en)
SE (1) SE367396B (en)
YU (12) YU33949B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
DE2309887C2 (en) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (en) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik ISOPROPYLAMINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
EP0025331B1 (en) * 1979-09-06 1983-03-02 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (en) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-PHENYL-2-AMINOCARBONYLINDOL COMPOUNDS AND METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
WO1985004580A1 (en) * 1984-04-09 1985-10-24 American Hospital Supply Corporation Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
ATE45724T1 (en) * 1985-12-24 1989-09-15 Merck & Co Inc OCULOSELECTIVE BETA BLOCKERS.
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
DK131029B (en) 1975-05-20
AT292676B (en) 1971-09-10
YU237474A (en) 1977-12-31
BR6804840D0 (en) 1973-03-08
FI49497C (en) 1975-07-10
YU237874A (en) 1977-12-31
NL7501792A (en) 1975-05-30
CH532015A (en) 1972-12-31
NL146709B (en) 1975-08-15
ES361189A1 (en) 1970-08-16
BG16445A3 (en) 1972-11-20
ES375447A1 (en) 1972-05-01
BG16331A3 (en) 1972-08-20
IL31266A0 (en) 1969-02-27
BE725490A (en) 1969-06-13
FI49497B (en) 1975-04-01
YU33853B (en) 1978-06-30
YU237774A (en) 1978-02-28
FR1596100A (en) 1970-06-15
NL151354B (en) 1976-11-15
AT292675B (en) 1971-09-10
AT292681B (en) 1971-08-15
YU33856B (en) 1978-06-30
YU294968A (en) 1978-02-28
YU238274A (en) 1977-12-31
AT292673B (en) 1971-09-10
YU33854B (en) 1978-06-30
ES375446A1 (en) 1972-05-01
YU33852B (en) 1978-06-30
CA954528A (en) 1974-09-10
YU33946B (en) 1978-09-08
ES375445A1 (en) 1972-05-16
BG16330A3 (en) 1972-08-20
BG19135A3 (en) 1975-04-30
YU33947B (en) 1978-09-08
AT298459B (en) 1972-05-10
YU33855B (en) 1978-06-30
YU33774B (en) 1978-05-15
NL6817768A (en) 1969-06-17
BG16444A3 (en) 1972-11-20
AT298463B (en) 1972-05-10
PH9266A (en) 1975-07-30
US3872147A (en) 1975-03-18
HU162734B (en) 1973-04-28
YU237674A (en) 1977-10-31
AT292678B (en) 1971-09-10
DE1643262C3 (en) 1975-06-26
BG16329A3 (en) 1972-08-20
CH556816A (en) 1974-12-13
AT292670B (en) 1971-09-10
BG16332A3 (en) 1972-08-20
BG17297A3 (en) 1973-07-25
YU238074A (en) 1977-12-31
YU33773B (en) 1978-05-15
YU238474A (en) 1978-02-28
AT292677B (en) 1971-09-10
FR8328M (en) 1970-12-07
ES375449A1 (en) 1972-05-01
DE1643262B2 (en) 1974-11-07
YU238374A (en) 1977-12-31
AT292680B (en) 1971-09-10
ES375448A1 (en) 1972-05-01
DK131029C (en) 1975-10-06
ES375444A1 (en) 1972-05-01
IE32758B1 (en) 1973-11-28
YU237974A (en) 1977-12-31
AT292679B (en) 1971-09-10
IE32758L (en) 1969-06-13
YU237574A (en) 1978-02-28
DE1643262A1 (en) 1972-04-20
JPS5220457B1 (en) 1977-06-03
ES375451A1 (en) 1972-05-01
YU33949B (en) 1978-09-08
NL7501794A (en) 1975-05-30
YU33948B (en) 1978-09-08
ES375450A1 (en) 1972-05-01
IL31266A (en) 1974-09-10
AT294799B (en) 1971-12-10
AT292674B (en) 1971-09-10
GB1260866A (en) 1972-01-19
YU33851B (en) 1978-06-30
SE367396B (en) 1974-05-27
ES375452A1 (en) 1972-05-16
BG17298A3 (en) 1973-07-25
ES375453A1 (en) 1972-05-16

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