NL146709B - PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOLYTIC ACTIVE ALXANDRO-3-PHEN-3-PHENROXANDY-3-ALXANDROXAMINES - Google Patents

PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOLYTIC ACTIVE ALXANDRO-3-PHEN-3-PHENROXANDY-3-ALXANDROXAMINES

Info

Publication number
NL146709B
NL146709B NL686817768A NL6817768A NL146709B NL 146709 B NL146709 B NL 146709B NL 686817768 A NL686817768 A NL 686817768A NL 6817768 A NL6817768 A NL 6817768A NL 146709 B NL146709 B NL 146709B
Authority
NL
Netherlands
Prior art keywords
adrenolytic
beta
phenroxandy
phenolytic
alxandroxamines
Prior art date
Application number
NL686817768A
Other languages
Dutch (nl)
Other versions
NL6817768A (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NL6817768A publication Critical patent/NL6817768A/xx
Priority to NL757501793A priority Critical patent/NL151356B/en
Publication of NL146709B publication Critical patent/NL146709B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
NL686817768A 1967-12-13 1968-12-11 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOLYTIC ACTIVE ALXANDRO-3-PHEN-3-PHENROXANDY-3-ALXANDROXAMINES NL146709B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL757501793A NL151356B (en) 1967-12-13 1975-02-14 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOLYTIC ACTIVE ALXANDRO-3-PHEN-3-PHENROXANDY-3-ALXANDROXAMINES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (en) 1967-12-13 1967-12-13 i-Phenoxy ^ -hydroxy-S-alklyaminopropane, process for their preparation and medicaments containing these compounds

Publications (2)

Publication Number Publication Date
NL6817768A NL6817768A (en) 1969-06-17
NL146709B true NL146709B (en) 1975-08-15

Family

ID=5684274

Family Applications (3)

Application Number Title Priority Date Filing Date
NL686817768A NL146709B (en) 1967-12-13 1968-12-11 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOLYTIC ACTIVE ALXANDRO-3-PHEN-3-PHENROXANDY-3-ALXANDROXAMINES
NL7501792A NL7501792A (en) 1967-12-13 1975-02-14 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH (BETA) -ADRENOLYTIC ACTION, THE OBJECTS OBTAINED BY THE APPLICATION OF THIS METHOD, AND A PROCESS FOR THE PREPARATION OF (BETA) -ADRENOLYTIC-ALKROXYTIC-ALKROXI-3-FENOLYTIC-ALKROXI-VAT-3-FENOLYTIC ALKROXAMAME 1-
NL757501794A NL151354B (en) 1967-12-13 1975-02-14 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOPHYL-3-PHENROXIVYL-3-PHENO-3-YK-3-Y-P-Y-P-D-I-P-D-I-P-D-I-P-D-I-P-Y-P-D-I-N-P-R-D-I-P-Y-D-I-T-D-I-T-D-I-T-D

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL7501792A NL7501792A (en) 1967-12-13 1975-02-14 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH (BETA) -ADRENOLYTIC ACTION, THE OBJECTS OBTAINED BY THE APPLICATION OF THIS METHOD, AND A PROCESS FOR THE PREPARATION OF (BETA) -ADRENOLYTIC-ALKROXYTIC-ALKROXI-3-FENOLYTIC-ALKROXI-VAT-3-FENOLYTIC ALKROXAMAME 1-
NL757501794A NL151354B (en) 1967-12-13 1975-02-14 PROCESS FOR THE PREPARATION OF A MEDICINAL PRODUCT WITH BETA-ADRENOLYTIC ACTION, THE MEDICINAL PRODUCTS OBTAINED BY THE APPLICATION OF THIS PROCESS, AND A PROCESS FOR PREPARING BETA-ADRENOLYTIC ALPINE-2-PHENOPHYL-3-PHENROXIVYL-3-PHENO-3-YK-3-Y-P-Y-P-D-I-P-D-I-P-D-I-P-D-I-P-Y-P-D-I-N-P-R-D-I-P-Y-D-I-T-D-I-T-D-I-T-D

Country Status (21)

Country Link
US (1) US3872147A (en)
JP (1) JPS5220457B1 (en)
AT (13) AT292675B (en)
BE (1) BE725490A (en)
BG (9) BG17298A3 (en)
BR (1) BR6804840D0 (en)
CA (1) CA954528A (en)
CH (2) CH532015A (en)
DE (1) DE1643262C3 (en)
DK (1) DK131029B (en)
ES (11) ES361189A1 (en)
FI (1) FI49497C (en)
FR (2) FR1596100A (en)
GB (1) GB1260866A (en)
HU (1) HU162734B (en)
IE (1) IE32758B1 (en)
IL (1) IL31266A (en)
NL (3) NL146709B (en)
PH (1) PH9266A (en)
SE (1) SE367396B (en)
YU (12) YU33949B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
DE2309887C2 (en) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (en) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik ISOPROPYLAMINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
EP0025331B1 (en) * 1979-09-06 1983-03-02 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (en) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-PHENYL-2-AMINOCARBONYLINDOL COMPOUNDS AND METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
DE3665168D1 (en) * 1985-12-24 1989-09-28 Merck & Co Inc Oculoselective beta blockers
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
NL151354B (en) 1976-11-15
YU33949B (en) 1978-09-08
AT294799B (en) 1971-12-10
SE367396B (en) 1974-05-27
IL31266A (en) 1974-09-10
AT292670B (en) 1971-09-10
ES361189A1 (en) 1970-08-16
AT292673B (en) 1971-09-10
AT292680B (en) 1971-09-10
YU237874A (en) 1977-12-31
BG16329A3 (en) 1972-08-20
ES375449A1 (en) 1972-05-01
AT292677B (en) 1971-09-10
YU33948B (en) 1978-09-08
YU33946B (en) 1978-09-08
ES375451A1 (en) 1972-05-01
AT298463B (en) 1972-05-10
FR1596100A (en) 1970-06-15
JPS5220457B1 (en) 1977-06-03
FI49497B (en) 1975-04-01
ES375453A1 (en) 1972-05-16
YU237774A (en) 1978-02-28
AT292681B (en) 1971-08-15
BG16445A3 (en) 1972-11-20
IL31266A0 (en) 1969-02-27
YU237474A (en) 1977-12-31
YU33853B (en) 1978-06-30
ES375448A1 (en) 1972-05-01
AT292675B (en) 1971-09-10
DE1643262A1 (en) 1972-04-20
YU33851B (en) 1978-06-30
YU237574A (en) 1978-02-28
AT292678B (en) 1971-09-10
YU238174A (en) 1977-10-31
NL7501792A (en) 1975-05-30
BG16331A3 (en) 1972-08-20
YU33774B (en) 1978-05-15
BG17297A3 (en) 1973-07-25
IE32758B1 (en) 1973-11-28
BG17298A3 (en) 1973-07-25
YU33854B (en) 1978-06-30
ES375444A1 (en) 1972-05-01
ES375450A1 (en) 1972-05-01
YU33947B (en) 1978-09-08
YU294968A (en) 1978-02-28
CA954528A (en) 1974-09-10
AT292676B (en) 1971-09-10
GB1260866A (en) 1972-01-19
ES375452A1 (en) 1972-05-16
YU33852B (en) 1978-06-30
YU33855B (en) 1978-06-30
DK131029C (en) 1975-10-06
BR6804840D0 (en) 1973-03-08
BG16444A3 (en) 1972-11-20
CH532015A (en) 1972-12-31
DK131029B (en) 1975-05-20
PH9266A (en) 1975-07-30
YU237974A (en) 1977-12-31
FR8328M (en) 1970-12-07
NL7501794A (en) 1975-05-30
US3872147A (en) 1975-03-18
BG16332A3 (en) 1972-08-20
HU162734B (en) 1973-04-28
AT292679B (en) 1971-09-10
YU238274A (en) 1977-12-31
ES375445A1 (en) 1972-05-16
YU238374A (en) 1977-12-31
YU237674A (en) 1977-10-31
BG19135A3 (en) 1975-04-30
YU33773B (en) 1978-05-15
DE1643262B2 (en) 1974-11-07
YU238074A (en) 1977-12-31
ES375447A1 (en) 1972-05-01
AT298459B (en) 1972-05-10
BG16330A3 (en) 1972-08-20
NL6817768A (en) 1969-06-17
CH556816A (en) 1974-12-13
IE32758L (en) 1969-06-13
ES375446A1 (en) 1972-05-01
YU33856B (en) 1978-06-30
BE725490A (en) 1969-06-13
DE1643262C3 (en) 1975-06-26
YU238474A (en) 1978-02-28
FI49497C (en) 1975-07-10
AT292674B (en) 1971-09-10

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Owner name: BOEHRINGER