ES375447A1 - 1-phenoxy-2-hydroxy-3-alkylamino-propanes - Google Patents

1-phenoxy-2-hydroxy-3-alkylamino-propanes

Info

Publication number
ES375447A1
ES375447A1 ES375447A ES375447A ES375447A1 ES 375447 A1 ES375447 A1 ES 375447A1 ES 375447 A ES375447 A ES 375447A ES 375447 A ES375447 A ES 375447A ES 375447 A1 ES375447 A1 ES 375447A1
Authority
ES
Spain
Prior art keywords
propanes
alkylamino
phenoxy
hydroxy
adrenolytics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES375447A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES375447A1 publication Critical patent/ES375447A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

The compounds are 1-phenoxy-2-hydroxy-3-alkylamino-propanes and non-toxic acid addition salts thereof, useful as beta -adrenolytics and hypotensives in warm-blooded animals.
ES375447A 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes Expired ES375447A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (en) 1967-12-13 1967-12-13 i-Phenoxy ^ -hydroxy-S-alklyaminopropane, process for their preparation and medicaments containing these compounds

Publications (1)

Publication Number Publication Date
ES375447A1 true ES375447A1 (en) 1972-05-01

Family

ID=5684274

Family Applications (11)

Application Number Title Priority Date Filing Date
ES361189A Expired ES361189A1 (en) 1967-12-13 1968-12-07 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375444A Expired ES375444A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375453A Expired ES375453A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375447A Expired ES375447A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375451A Expired ES375451A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375445A Expired ES375445A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375452A Expired ES375452A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375449A Expired ES375449A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375450A Expired ES375450A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375446A Expired ES375446A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375448A Expired ES375448A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES361189A Expired ES361189A1 (en) 1967-12-13 1968-12-07 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375444A Expired ES375444A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375453A Expired ES375453A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes

Family Applications After (7)

Application Number Title Priority Date Filing Date
ES375451A Expired ES375451A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375445A Expired ES375445A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375452A Expired ES375452A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375449A Expired ES375449A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375450A Expired ES375450A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375446A Expired ES375446A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes
ES375448A Expired ES375448A1 (en) 1967-12-13 1970-01-15 1-phenoxy-2-hydroxy-3-alkylamino-propanes

Country Status (21)

Country Link
US (1) US3872147A (en)
JP (1) JPS5220457B1 (en)
AT (13) AT292670B (en)
BE (1) BE725490A (en)
BG (9) BG17298A3 (en)
BR (1) BR6804840D0 (en)
CA (1) CA954528A (en)
CH (2) CH532015A (en)
DE (1) DE1643262C3 (en)
DK (1) DK131029B (en)
ES (11) ES361189A1 (en)
FI (1) FI49497C (en)
FR (2) FR1596100A (en)
GB (1) GB1260866A (en)
HU (1) HU162734B (en)
IE (1) IE32758B1 (en)
IL (1) IL31266A (en)
NL (3) NL146709B (en)
PH (1) PH9266A (en)
SE (1) SE367396B (en)
YU (12) YU33949B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2309887C2 (en) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (en) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik ISOPROPYLAMINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
EP0025331B1 (en) * 1979-09-06 1983-03-02 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (en) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-PHENYL-2-AMINOCARBONYLINDOL COMPOUNDS AND METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
WO1985004580A1 (en) * 1984-04-09 1985-10-24 American Hospital Supply Corporation Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
ES2011255B3 (en) * 1985-12-24 1990-01-01 Merck & Co Inc SELECTIVE BETA LOCKERS FOR EYES.
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
ES375452A1 (en) 1972-05-16
YU33852B (en) 1978-06-30
BE725490A (en) 1969-06-13
JPS5220457B1 (en) 1977-06-03
YU238274A (en) 1977-12-31
YU33854B (en) 1978-06-30
YU238474A (en) 1978-02-28
YU237474A (en) 1977-12-31
AT292679B (en) 1971-09-10
IL31266A0 (en) 1969-02-27
YU237974A (en) 1977-12-31
BG19135A3 (en) 1975-04-30
PH9266A (en) 1975-07-30
NL7501792A (en) 1975-05-30
ES361189A1 (en) 1970-08-16
ES375451A1 (en) 1972-05-01
CH532015A (en) 1972-12-31
YU33948B (en) 1978-09-08
YU33856B (en) 1978-06-30
YU237874A (en) 1977-12-31
AT292681B (en) 1971-08-15
BG16331A3 (en) 1972-08-20
YU294968A (en) 1978-02-28
YU237674A (en) 1977-10-31
AT292677B (en) 1971-09-10
ES375444A1 (en) 1972-05-01
YU33853B (en) 1978-06-30
ES375449A1 (en) 1972-05-01
YU33949B (en) 1978-09-08
ES375446A1 (en) 1972-05-01
YU33855B (en) 1978-06-30
YU33773B (en) 1978-05-15
NL6817768A (en) 1969-06-17
AT292674B (en) 1971-09-10
DE1643262A1 (en) 1972-04-20
FI49497B (en) 1975-04-01
GB1260866A (en) 1972-01-19
YU238374A (en) 1977-12-31
DE1643262C3 (en) 1975-06-26
AT292670B (en) 1971-09-10
SE367396B (en) 1974-05-27
BG16444A3 (en) 1972-11-20
AT292678B (en) 1971-09-10
ES375445A1 (en) 1972-05-16
YU33774B (en) 1978-05-15
DE1643262B2 (en) 1974-11-07
BG16332A3 (en) 1972-08-20
YU238074A (en) 1977-12-31
NL7501794A (en) 1975-05-30
NL151354B (en) 1976-11-15
BG16330A3 (en) 1972-08-20
IL31266A (en) 1974-09-10
IE32758B1 (en) 1973-11-28
AT294799B (en) 1971-12-10
BG17298A3 (en) 1973-07-25
AT292675B (en) 1971-09-10
HU162734B (en) 1973-04-28
YU238174A (en) 1977-10-31
CA954528A (en) 1974-09-10
DK131029C (en) 1975-10-06
BG16445A3 (en) 1972-11-20
AT292680B (en) 1971-09-10
FR1596100A (en) 1970-06-15
YU33947B (en) 1978-09-08
US3872147A (en) 1975-03-18
FR8328M (en) 1970-12-07
YU237774A (en) 1978-02-28
AT298463B (en) 1972-05-10
ES375453A1 (en) 1972-05-16
BG17297A3 (en) 1973-07-25
NL146709B (en) 1975-08-15
IE32758L (en) 1969-06-13
AT292673B (en) 1971-09-10
DK131029B (en) 1975-05-20
BG16329A3 (en) 1972-08-20
CH556816A (en) 1974-12-13
ES375448A1 (en) 1972-05-01
AT292676B (en) 1971-09-10
FI49497C (en) 1975-07-10
YU237574A (en) 1978-02-28
YU33946B (en) 1978-09-08
YU33851B (en) 1978-06-30
AT298459B (en) 1972-05-10
BR6804840D0 (en) 1973-03-08
ES375450A1 (en) 1972-05-01

Similar Documents

Publication Publication Date Title
ES375452A1 (en) 1-phenoxy-2-hydroxy-3-alkylamino-propanes
DK118611B (en) 3,4-cis-4-Aryl isoflavanes and acid addition salts thereof for use in antifertility agents.
YU59768A (en) Postopek za pripravo 1,4-dihidropiridinov s formulo i
DK131076B (en) Stable, especially pigsty.
MY7400292A (en) 9, 10-dihydrolysergic acid derivative
IL36529A0 (en) Substituted s-triazines,their preparation and their use as herbicides
MY7300299A (en) 5-imino-1,2,4-triazine derivatives an their use as herbicides
IL30706A0 (en) 2-halomethyl-3-carbamyl quinoxaline-1,4,-di-n-oxides
CH556642A (en) FORAGE PLANTS FORWARD.
IL37520A (en) S-triazines,their manufacture and their use as herbicides
ZA711049B (en) Substituted 6-nitroaniline derivatives,processes for their preparation,and their use as herbicidal agents
CA927661A (en) Guanidines employed in animal husbandry
IL36813A0 (en) Pyrimidine derivatives,their preparation and their use as herbicides
CA783566A (en) 4,4'-bis(4-anilino-6-morpholino-s-triazin-2-ylamino-2,2'-stilbenedisulfonic acid
CA751482A (en) 2,3,6-trichloro-5-nitrobenzoic acid and the salts thereof
CA745628A (en) N,n-di-lower-alkylhydroxylamine salts
CA716586A (en) 3,6-endoxohydrophthalic acid amine salts
CA950905A (en) 9,10-dihydro-ergonine and its salts
CA783070A (en) 2,3,6-trichloromandelic acid as herbicide
ES158353Y (en) PERFECTED BATTERY CHARGER.
YU32846B (en) Univerzalno kuciste za alate, za prosecanje, izvlacenje, savijanje i oblikovanje
CA757622A (en) Basic 1,3-dioxanes, their salts and process
CA853742A (en) 2,2'-dithiocaproic acid and its water soluble salts
AU447363B2 (en) 2-halomethyl-3-carboxylic acid amidoquinoxaline-1, 4-di-n-oxides
ES153909Y (en) ANATOMICAL WOOD.