CH532015A - Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes - Google Patents

Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes

Info

Publication number
CH532015A
CH532015A CH1843568A CH1843568A CH532015A CH 532015 A CH532015 A CH 532015A CH 1843568 A CH1843568 A CH 1843568A CH 1843568 A CH1843568 A CH 1843568A CH 532015 A CH532015 A CH 532015A
Authority
CH
Switzerland
Prior art keywords
alkylaminopropanes
phenoxy
hydroxy
preparation
new
Prior art date
Application number
CH1843568A
Other languages
German (de)
Inventor
Herbert Dr Koeppe
Werner Dr Kummer
Helmut Dr Staehle
Zeile Karl Dr Prof
Albrecht Dr Engelhardt
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CH848071A priority Critical patent/CH530954A/en
Priority to CH847971A priority patent/CH532019A/en
Priority to CH848371A priority patent/CH515885A/en
Priority to CH847871A priority patent/CH532018A/en
Priority to CH848171A priority patent/CH530955A/en
Priority to CH847771A priority patent/CH532017A/en
Priority to CH847671A priority patent/CH532016A/en
Priority to CH848271A priority patent/CH530956A/en
Priority to CH848571A priority patent/CH530957A/en
Publication of CH532015A publication Critical patent/CH532015A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1843568A 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes CH532015A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CH848071A CH530954A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH847971A CH532019A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH848371A CH515885A (en) 1967-12-13 1968-12-10 1-phenoxy-2-hydroxy-3-alkylamino propanes adrenolytic
CH847871A CH532018A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH848171A CH530955A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH847771A CH532017A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH847671A CH532016A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH848271A CH530956A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes
CH848571A CH530957A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1643262A DE1643262C3 (en) 1967-12-13 1967-12-13 i-Phenoxy ^ -hydroxy-S-alklyaminopropane, process for their preparation and medicaments containing these compounds

Publications (1)

Publication Number Publication Date
CH532015A true CH532015A (en) 1972-12-31

Family

ID=5684274

Family Applications (2)

Application Number Title Priority Date Filing Date
CH848471A CH556816A (en) 1967-12-13 1968-12-10 PROCESS FOR THE PRODUCTION OF NEW 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPANES.
CH1843568A CH532015A (en) 1967-12-13 1968-12-10 Process for the preparation of new 1-phenoxy-2-hydroxy-3-alkylaminopropanes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH848471A CH556816A (en) 1967-12-13 1968-12-10 PROCESS FOR THE PRODUCTION OF NEW 1-PHENOXY-2-HYDROXY-3-ALKYLAMINOPROPANES.

Country Status (21)

Country Link
US (1) US3872147A (en)
JP (1) JPS5220457B1 (en)
AT (13) AT292679B (en)
BE (1) BE725490A (en)
BG (9) BG17298A3 (en)
BR (1) BR6804840D0 (en)
CA (1) CA954528A (en)
CH (2) CH556816A (en)
DE (1) DE1643262C3 (en)
DK (1) DK131029B (en)
ES (11) ES361189A1 (en)
FI (1) FI49497C (en)
FR (2) FR1596100A (en)
GB (1) GB1260866A (en)
HU (1) HU162734B (en)
IE (1) IE32758B1 (en)
IL (1) IL31266A (en)
NL (3) NL146709B (en)
PH (1) PH9266A (en)
SE (1) SE367396B (en)
YU (12) YU33949B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
US3998874A (en) * 1971-03-23 1976-12-21 Gist-Brocades N.V. Phenylene di-ethers
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2309887C2 (en) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US4161530A (en) * 1975-01-06 1979-07-17 Ciba-Geigy Corporation Pharmaceutical combination preparations as hypnotics
US4094991A (en) * 1975-06-17 1978-06-13 Nippon Shinyaku Co., Ltd. Substituted n-(carboxymethyl)-3-aminopropan-2-ol derivatives
US4243681A (en) * 1977-10-11 1981-01-06 Mead Johnson & Company Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof
DE2839475A1 (en) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik ISOPROPYLAMINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THE SAME
DE3062216D1 (en) * 1979-09-06 1983-04-07 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
JPS56142262A (en) 1980-04-08 1981-11-06 Nippon Shinyaku Co Ltd Piperazine derivative
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4405642A (en) * 1980-11-28 1983-09-20 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4396629A (en) * 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method
DE3131527A1 (en) * 1981-08-08 1983-02-24 Kali-Chemie Pharma Gmbh, 3000 Hannover 1-PHENYL-2-AMINOCARBONYLINDOL COMPOUNDS AND METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
JPH0720861B2 (en) * 1984-04-09 1995-03-08 ザ デュポン マーク ファーマソウテイカル カンパニー Pharmaceutical compositions and methods for the treatment or prevention of heart disorders
US4652584A (en) * 1984-07-13 1987-03-24 Mcneilab, Inc. Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
DE3665168D1 (en) * 1985-12-24 1989-09-28 Merck & Co Inc Oculoselective beta blockers
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes

Also Published As

Publication number Publication date
DE1643262B2 (en) 1974-11-07
SE367396B (en) 1974-05-27
YU33946B (en) 1978-09-08
FI49497B (en) 1975-04-01
AT292676B (en) 1971-09-10
ES375445A1 (en) 1972-05-16
YU238074A (en) 1977-12-31
IL31266A (en) 1974-09-10
ES375448A1 (en) 1972-05-01
YU33947B (en) 1978-09-08
ES361189A1 (en) 1970-08-16
BE725490A (en) 1969-06-13
NL7501792A (en) 1975-05-30
CA954528A (en) 1974-09-10
AT292670B (en) 1971-09-10
PH9266A (en) 1975-07-30
ES375451A1 (en) 1972-05-01
YU33948B (en) 1978-09-08
YU33856B (en) 1978-06-30
YU33949B (en) 1978-09-08
YU237674A (en) 1977-10-31
ES375450A1 (en) 1972-05-01
YU33853B (en) 1978-06-30
JPS5220457B1 (en) 1977-06-03
DK131029B (en) 1975-05-20
DE1643262A1 (en) 1972-04-20
YU238474A (en) 1978-02-28
DK131029C (en) 1975-10-06
AT292674B (en) 1971-09-10
AT292678B (en) 1971-09-10
YU237974A (en) 1977-12-31
YU238174A (en) 1977-10-31
AT298463B (en) 1972-05-10
YU237874A (en) 1977-12-31
ES375447A1 (en) 1972-05-01
YU33854B (en) 1978-06-30
FR8328M (en) 1970-12-07
NL6817768A (en) 1969-06-17
BG17298A3 (en) 1973-07-25
BG16330A3 (en) 1972-08-20
FI49497C (en) 1975-07-10
AT292680B (en) 1971-09-10
IE32758B1 (en) 1973-11-28
YU237574A (en) 1978-02-28
ES375449A1 (en) 1972-05-01
YU33852B (en) 1978-06-30
FR1596100A (en) 1970-06-15
BG16332A3 (en) 1972-08-20
BG16445A3 (en) 1972-11-20
YU237474A (en) 1977-12-31
BG17297A3 (en) 1973-07-25
BG19135A3 (en) 1975-04-30
BG16329A3 (en) 1972-08-20
CH556816A (en) 1974-12-13
NL151354B (en) 1976-11-15
NL146709B (en) 1975-08-15
AT294799B (en) 1971-12-10
AT292681B (en) 1971-08-15
BR6804840D0 (en) 1973-03-08
YU33855B (en) 1978-06-30
GB1260866A (en) 1972-01-19
YU294968A (en) 1978-02-28
YU238374A (en) 1977-12-31
US3872147A (en) 1975-03-18
DE1643262C3 (en) 1975-06-26
YU33774B (en) 1978-05-15
BG16444A3 (en) 1972-11-20
IL31266A0 (en) 1969-02-27
AT298459B (en) 1972-05-10
AT292679B (en) 1971-09-10
ES375444A1 (en) 1972-05-01
YU33851B (en) 1978-06-30
IE32758L (en) 1969-06-13
HU162734B (en) 1973-04-28
BG16331A3 (en) 1972-08-20
ES375446A1 (en) 1972-05-01
YU33773B (en) 1978-05-15
AT292675B (en) 1971-09-10
NL7501794A (en) 1975-05-30
ES375452A1 (en) 1972-05-16
ES375453A1 (en) 1972-05-16
YU238274A (en) 1977-12-31
YU237774A (en) 1978-02-28
AT292673B (en) 1971-09-10
AT292677B (en) 1971-09-10

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Legal Events

Date Code Title Description
PL Patent ceased