ES357714A2 - Process for the manufacture of 7-aminocephalosporanic acid - Google Patents
Process for the manufacture of 7-aminocephalosporanic acidInfo
- Publication number
- ES357714A2 ES357714A2 ES357714A ES357714A ES357714A2 ES 357714 A2 ES357714 A2 ES 357714A2 ES 357714 A ES357714 A ES 357714A ES 357714 A ES357714 A ES 357714A ES 357714 A2 ES357714 A2 ES 357714A2
- Authority
- ES
- Spain
- Prior art keywords
- group
- aminocephalosporanic acid
- silyloxy
- imide
- halide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 2
- 125000004469 siloxy group Chemical group [SiH3]O* 0.000 abstract 2
- -1 stannyloxy group Chemical group 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2224—Compounds having one or more tin-oxygen linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
7-Aminocephalosporanic acid is produced by treating a compound of Formula I: wherein Y is a protected NH 2 group and OR is a silyloxy or stannyloxy group, with an agent forming an imide-halide, the imide-halide is treated with an alcohol to form an imino-ether, whereby at the same time the silyloxy or stannyloxy group is split off, and the iminoether is hydrolysed to yield 7-aminocephalosporanic acid. The operations are carried out by known methods, e.g. as in the parent Specification. The ester group OR in the compound of Formula I may be wherein R 1 , R 2 and R 3 are the same or different and are alkyl, aralkyl or aryl. The protected NH 2 group may be N,N-phthaloylamino, N- 2,4,6 - trinitrophenylamino, N - silylamino, N- stannylanaino or a protonated amino group.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1232967 | 1967-09-01 | ||
| CH883268A CH517119A (en) | 1967-09-01 | 1968-06-14 | New process for the production of 7-aminocephalosporanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES357714A2 true ES357714A2 (en) | 1970-04-01 |
Family
ID=25703829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES357714A Expired ES357714A2 (en) | 1967-09-01 | 1968-08-30 | Process for the manufacture of 7-aminocephalosporanic acid |
Country Status (13)
| Country | Link |
|---|---|
| JP (3) | JPS524557B1 (en) |
| AT (1) | AT299447B (en) |
| BE (1) | BE720185A (en) |
| CH (1) | CH517119A (en) |
| CS (1) | CS159748B2 (en) |
| DE (2) | DE1795209C3 (en) |
| DK (1) | DK144701C (en) |
| ES (1) | ES357714A2 (en) |
| GB (1) | GB1244191A (en) |
| IT (1) | IT1045676B (en) |
| NL (1) | NL166263C (en) |
| SE (1) | SE364285B (en) |
| YU (2) | YU35259B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54164550U (en) * | 1978-05-10 | 1979-11-17 | ||
| IL63942A (en) * | 1981-09-27 | 1988-07-31 | Zwi Schwartz | Beverage bag provided with rigid hanging means |
| JPH0420652A (en) * | 1990-05-15 | 1992-01-24 | Tooma:Kk | Wooden tile |
| US7591219B2 (en) | 2004-05-26 | 2009-09-22 | Pamela Saha | Disposable combined squeezer/stirrer/dispenser/brewer device |
| US7849785B1 (en) | 2005-05-18 | 2010-12-14 | Pamela Saha | Disposable combined squeezer/stirrer/dispenser/brewer device with bottom cup |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK118506B (en) * | 1963-02-18 | 1970-08-31 | Ciba Geigy | Process for the preparation of 7-aminocephalosporanic acid or esters thereof. |
-
1968
- 1968-06-14 CH CH883268A patent/CH517119A/en not_active IP Right Cessation
- 1968-08-23 DE DE1795209A patent/DE1795209C3/en not_active Expired
- 1968-08-23 DE DE1795868A patent/DE1795868C3/en not_active Expired
- 1968-08-26 GB GB40708/68A patent/GB1244191A/en not_active Expired
- 1968-08-29 YU YU2024/68A patent/YU35259B/en unknown
- 1968-08-30 DK DK419368A patent/DK144701C/en not_active IP Right Cessation
- 1968-08-30 ES ES357714A patent/ES357714A2/en not_active Expired
- 1968-08-30 NL NL6812413.A patent/NL166263C/en not_active IP Right Cessation
- 1968-08-30 AT AT845268A patent/AT299447B/en not_active IP Right Cessation
- 1968-08-30 BE BE720185D patent/BE720185A/xx unknown
- 1968-08-30 SE SE11670/68A patent/SE364285B/xx unknown
- 1968-08-30 IT IT39408/68A patent/IT1045676B/en active
- 1968-08-30 JP JP43061852A patent/JPS524557B1/ja active Pending
- 1968-09-02 CS CS6177A patent/CS159748B2/cs unknown
-
1974
- 1974-07-01 JP JP49074387A patent/JPS5233119B1/ja active Pending
- 1974-07-11 YU YU1952/74A patent/YU36735B/en unknown
-
1976
- 1976-02-07 JP JP51011862A patent/JPS525520B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| YU36735B (en) | 1984-08-31 |
| AT299447B (en) | 1972-06-26 |
| JPS524557B1 (en) | 1977-02-04 |
| JPS525520B1 (en) | 1977-02-14 |
| JPS5233119B1 (en) | 1977-08-26 |
| BE720185A (en) | 1969-02-28 |
| YU35259B (en) | 1980-10-31 |
| NL6812413A (en) | 1969-03-04 |
| DK144701B (en) | 1982-05-17 |
| YU202468A (en) | 1980-04-30 |
| DE1795209A1 (en) | 1971-12-30 |
| YU195274A (en) | 1982-06-18 |
| NL166263B (en) | 1981-02-16 |
| DE1795209C3 (en) | 1980-03-13 |
| DE1795868C3 (en) | 1981-11-12 |
| NL166263C (en) | 1981-07-15 |
| IT1045676B (en) | 1980-06-10 |
| CH517119A (en) | 1971-12-31 |
| GB1244191A (en) | 1971-08-25 |
| DK144701C (en) | 1982-10-11 |
| DE1795209B2 (en) | 1979-07-12 |
| DE1795868B1 (en) | 1981-01-08 |
| CS159748B2 (en) | 1975-01-31 |
| SE364285B (en) | 1974-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170630 |