ES357105A1 - 4-(4-fluorophenyl)phenyl acylates and their production and use - Google Patents

4-(4-fluorophenyl)phenyl acylates and their production and use

Info

Publication number
ES357105A1
ES357105A1 ES357105A ES357105A ES357105A1 ES 357105 A1 ES357105 A1 ES 357105A1 ES 357105 A ES357105 A ES 357105A ES 357105 A ES357105 A ES 357105A ES 357105 A1 ES357105 A1 ES 357105A1
Authority
ES
Spain
Prior art keywords
triphenylphosphine
fluorophenyl
tris
formula
acylates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES357105A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES357105A1 publication Critical patent/ES357105A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C07C37/0555—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group being esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Exhaust Gas Treatment By Means Of Catalyst (AREA)

Abstract

Novel compounds of the formula wherein Z is an acyl radical (e.g. benzoyl), are obtained by reacting a compound of the formula (see Specification 1,209,539) with a transition metal or complex thereof, e.g. tris-(triphenylphosphine) rhodium fluoride, tris-(triphenylphosphine) rhodium chloride, tetrakis (triphenylphosphine) ruthenium dichloride, bis- (triphenylphosphine) ruthenium carbonyl chloride, cobalt carbonyl, platinum and palladium. The novel compounds may be subjected to solvolysis to yield 4-(4-fluorophenyl) phenol and the latter may be reacted with carbon dioxide in the presence of a basic catalyst to produce 5-(4- fluorophenyl) salicylic acid and the latter may be O-acetylated. This acetylation step is described and caimed in Specification 1,204,970.
ES357105A 1967-08-14 1968-08-09 4-(4-fluorophenyl)phenyl acylates and their production and use Expired ES357105A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA997836 1967-08-14

Publications (1)

Publication Number Publication Date
ES357105A1 true ES357105A1 (en) 1970-03-01

Family

ID=4142994

Family Applications (1)

Application Number Title Priority Date Filing Date
ES357105A Expired ES357105A1 (en) 1967-08-14 1968-08-09 4-(4-fluorophenyl)phenyl acylates and their production and use

Country Status (10)

Country Link
BE (1) BE719414A (en)
CH (1) CH500935A (en)
DE (1) DE1793144A1 (en)
ES (1) ES357105A1 (en)
FR (1) FR1576260A (en)
GB (2) GB1209539A (en)
IL (1) IL30498A0 (en)
NL (1) NL6811555A (en)
NO (1) NO124686B (en)
SE (1) SE353527B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1152282B (en) * 1960-08-22 1963-08-01 Blackwelder Mfg Co Device for thinning out rows of plants
US3965146A (en) * 1973-06-04 1976-06-22 Raychem Corporation Biphenylyloxy benzoic acid and esters thereof
US4237315A (en) * 1979-11-02 1980-12-02 Merck & Co., Inc. Preparation of 5(halophenyl)salicylic acid compounds
EP1620420A2 (en) 2003-04-30 2006-02-01 The Institutes for Pharmaceutical Discovery, LLC Substituted carboxylic acids
CA2585550A1 (en) * 2004-10-28 2006-05-11 The Institutes For Pharmaceutical Discovery, Llc Substituted carboxylic acids

Also Published As

Publication number Publication date
DE1793144A1 (en) 1972-02-03
SE353527B (en) 1973-02-05
NL6811555A (en) 1969-02-18
GB1209539A (en) 1970-10-21
GB1209538A (en) 1970-10-21
CH500935A (en) 1970-12-31
IL30498A0 (en) 1968-10-24
NO124686B (en) 1972-05-23
BE719414A (en) 1969-02-13
FR1576260A (en) 1969-07-25

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