ES354102A1 - Procedure for the obtaining of ammonium salts of medicinal application. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of ammonium salts of medicinal application. (Machine-translation by Google Translate, not legally binding)
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VILADOT VENDRELL
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VILADOT VENDRELL
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Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Process for obtaining physiologically tolerable ammonium salts of medicinal application, such as the 2-amino-3'5-dihalobenzylammonium salts of: ** (see formula) ** Wherein x represents a chlorine or hydrogen atom, hydrogen r, saturated lower alkyl radicals, cycloalkyl, aralkyl or aryl radicals, r'saturated lower alkyl radicals, aralkyl or aryl cycloalkyl radicals, r and r'together, a chain of 4 to 5 carbon atoms forming with the nitrogen a ring of pyrrolidine or piperidine, and ah, an inorganic acid such as hydrochloric, hydrochloric or sulfuric, characterized by reacting 2-amino 3'5 -dihalogenbenzaldehydes of the ** (see formula) ** With amines ** (see formula) ** Where r and r'have the meaning indicated above, in the presence of hydrogen and of an appropriate reduction catalyst such as raney nickel, platinum or palladium, further transforming the 2-amino-3'5-dihalobenzylamines of ** (see formula) ** Thus obtained in the corresponding ammonium salt by reaction with the chosen inorganic acid. (Machine-translation by Google Translate, not legally binding)
ES354102A1968-05-201968-05-20Procedure for the obtaining of ammonium salts of medicinal application. (Machine-translation by Google Translate, not legally binding)
ExpiredES354102A1
(en)
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