ES353268A1 - Procedimiento para preparar 7,8-dihidro-6-(alcoxi inferior)-6, 14-endo (eteno y etano) morfida-7-cetonas. - Google Patents
Procedimiento para preparar 7,8-dihidro-6-(alcoxi inferior)-6, 14-endo (eteno y etano) morfida-7-cetonas.Info
- Publication number
- ES353268A1 ES353268A1 ES353268A ES353268A ES353268A1 ES 353268 A1 ES353268 A1 ES 353268A1 ES 353268 A ES353268 A ES 353268A ES 353268 A ES353268 A ES 353268A ES 353268 A1 ES353268 A1 ES 353268A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- alkyl
- compounds
- group
- represents hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- -1 cyano, propargyl Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000011260 aqueous acid Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000002084 enol ethers Chemical class 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- JMANVNJQNLATNU-UHFFFAOYSA-N glycolonitrile Natural products N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
- C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
- C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63411667A | 1967-04-27 | 1967-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES353268A1 true ES353268A1 (es) | 1970-02-01 |
Family
ID=24542502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES353268A Expired ES353268A1 (es) | 1967-04-27 | 1968-04-27 | Procedimiento para preparar 7,8-dihidro-6-(alcoxi inferior)-6, 14-endo (eteno y etano) morfida-7-cetonas. |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT289303B (en:Method) |
| BE (1) | BE714349A (en:Method) |
| CH (1) | CH507250A (en:Method) |
| DE (1) | DE1770287A1 (en:Method) |
| ES (1) | ES353268A1 (en:Method) |
| FR (2) | FR1589058A (en:Method) |
| GB (1) | GB1223444A (en:Method) |
| IL (1) | IL29798A0 (en:Method) |
| LU (1) | LU55980A1 (en:Method) |
| NL (1) | NL6805648A (en:Method) |
-
1968
- 1968-04-09 IL IL29798A patent/IL29798A0/xx unknown
- 1968-04-22 FR FR1589058D patent/FR1589058A/fr not_active Expired
- 1968-04-22 NL NL6805648A patent/NL6805648A/xx unknown
- 1968-04-26 DE DE19681770287 patent/DE1770287A1/de active Pending
- 1968-04-26 BE BE714349D patent/BE714349A/xx unknown
- 1968-04-26 LU LU55980D patent/LU55980A1/xx unknown
- 1968-04-26 GB GB08457/68A patent/GB1223444A/en not_active Expired
- 1968-04-26 FR FR149553A patent/FR7483M/fr not_active Expired
- 1968-04-26 AT AT412468A patent/AT289303B/de not_active IP Right Cessation
- 1968-04-27 ES ES353268A patent/ES353268A1/es not_active Expired
- 1968-04-29 CH CH634068A patent/CH507250A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL6805648A (en:Method) | 1968-10-28 |
| GB1223444A (en) | 1971-02-24 |
| FR1589058A (en:Method) | 1970-03-23 |
| BE714349A (en:Method) | 1968-10-28 |
| FR7483M (en:Method) | 1969-12-01 |
| DE1770287A1 (de) | 1971-10-21 |
| CH507250A (de) | 1971-05-15 |
| IL29798A0 (en) | 1968-06-20 |
| LU55980A1 (en:Method) | 1968-07-12 |
| AT289303B (de) | 1971-04-13 |
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