ES343019A1 - Procedure for the obtaining of new phenyl-alcanolamines. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of new phenyl-alcanolamines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES343019A1 ES343019A1 ES343019A ES343019A ES343019A1 ES 343019 A1 ES343019 A1 ES 343019A1 ES 343019 A ES343019 A ES 343019A ES 343019 A ES343019 A ES 343019A ES 343019 A1 ES343019 A1 ES 343019A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- compound
- see formula
- represents hydrogen
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A procedure for obtaining compounds of the general formula **(See formula)** in which R1 represents hydrogen or an acyl group, especially the radical of an aliphatic or aromatic carboxylic acid or an N-substituted carbamic acid, R2 represents a straight or branched lower alcohol group R3 is hydrogen or an alcohol group with 1 to 3 atoms Carbon and R4 is hydrogen, a straight or branched lower alcohol group, an acyl, formyl, carboalkoxy- or theophylline (7) -ethyl group, as well as its addition salts with physiologically tolerable acids characterized by reducing a) a compound of the general formula **(See formula)** in which R2, R3 and R4 have the indicated meanings and R represents the group R1 or a hydrogenolytic, hydrolytic or alcoholically separable protecting group, especially a benzyl or acyl group and R'represents hydrogen or, especially its R4 represents hydrogen or a group alcohol or a theophylline (7) -ethyl group, a protecting group, preferably a benzyl group, or reduce b) a compound of the general formula **(See formula)** in which R and R2 have the indicated meanings and Q represents the group (see formula), (in which R7 represents hydrogen or a straight or branched lower alcohol group) or the group (see formula) or reduce c) a compound of the general formula **(See formula)** in which R, R2 and R3 have the indicated meanings and R6 represents = C = O or = COHO groups, in the presence of a compound R5-NH2, in which R5 represents hydrogen, a straight or branched lower alcohol group or a group theophylline (7) -ethyl, or d) cleaving by the action of strong acids a compound of the general formula **(See formula)** in which R, R3 and R7 have the meanings indicated above or e) reacting a compound of the general formula **(See formula)** in which R2 has the meaning indicated above, E represents the group (see formula), or the group (see formula), (Y is a chlorine, bromine or iodine atom); and R'''represents a protecting group, preferably the benzyl group, with a compound of the general formula R5-NH-R'', in which R5 has the meaning indicated above and R''represents hydrogen or a benzyl group, and separating from the compounds obtained according to the working methods a) to e) possibly present protecting groups and optionally introducing into the compounds of formula I thus obtained, in which R1 represents hydrogen, an acyl group, and/or in which R4 represents hydrogen, a lower alcohol group, acyl, formyl, carboalkoxy or theophylline (7) -ethyl, and, optionally, converting the free bases obtained at the beginning into the acid addition salts and the salts obtained at the beginning into the free bases. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0088050 | 1966-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES343019A1 true ES343019A1 (en) | 1968-08-16 |
Family
ID=6984091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES343019A Expired ES343019A1 (en) | 1966-07-18 | 1967-07-14 | Procedure for the obtaining of new phenyl-alcanolamines. (Machine-translation by Google Translate, not legally binding) |
Country Status (6)
| Country | Link |
|---|---|
| AT (3) | AT287680B (en) |
| BE (1) | BE701499A (en) |
| DE (1) | DE1543359A1 (en) |
| ES (1) | ES343019A1 (en) |
| FR (1) | FR7177M (en) |
| NL (1) | NL6709934A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2933005C2 (en) * | 1979-08-14 | 1983-01-13 | Klinge Pharma GmbH, 8000 München | 1- (3-Acyloxyphenyl) -2-aminoethanols, their acid addition salts, medicaments containing them, and processes for their preparation |
-
1966
- 1966-07-18 DE DE19661543359 patent/DE1543359A1/en active Granted
-
1967
- 1967-07-14 AT AT957469A patent/AT287680B/en active
- 1967-07-14 AT AT663267A patent/AT287677B/en not_active IP Right Cessation
- 1967-07-14 AT AT09575/69A patent/AT287681B/en active
- 1967-07-14 ES ES343019A patent/ES343019A1/en not_active Expired
- 1967-07-18 BE BE701499D patent/BE701499A/xx unknown
- 1967-07-18 NL NL6709934A patent/NL6709934A/xx unknown
- 1967-10-18 FR FR124951A patent/FR7177M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE701499A (en) | 1968-01-18 |
| NL6709934A (en) | 1968-01-19 |
| AT287677B (en) | 1971-02-10 |
| FR7177M (en) | 1969-08-11 |
| DE1543359A1 (en) | 1972-04-13 |
| AT287680B (en) | 1971-02-10 |
| AT287681B (en) | 1971-02-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES369570A1 (en) | New thiadiazolyl-ureas, their production and composition containing same | |
| GB1233194A (en) | ||
| ES416891A1 (en) | Esters of carboxymethyloxysuccinic acid and derivatives thereof | |
| ES454086A1 (en) | Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -norosimorphone new. (Machine-translation by Google Translate, not legally binding) | |
| ES453304A1 (en) | Amino acid derivatives | |
| ES343019A1 (en) | Procedure for the obtaining of new phenyl-alcanolamines. (Machine-translation by Google Translate, not legally binding) | |
| ES321531A1 (en) | Procedure for the manufacture of new 7- (picolilaminoalquilteofilinas). (Machine-translation by Google Translate, not legally binding) | |
| ES381582A1 (en) | Hexahydro-fluoren-2-yloxy alkanoic acids and esters thereof | |
| ES386846A1 (en) | Hydroxamic acid derivatives of alphaaminooxy carboxylic acids | |
| ES385091A1 (en) | Beta-(2,4,6-triiodo-3-acetamidinophenyl)-propionic acids | |
| ES410060A1 (en) | Resolution of dl-allethrolone | |
| ES380057A1 (en) | Procedure for the preparation of new indol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| JPS55151555A (en) | Proline derivatives and their production | |
| ES297640A1 (en) | Procedure for the obtaining of aminic compounds (Machine-translation by Google Translate, not legally binding) | |
| GB1270120A (en) | Pyrimidine carboxylic acid ester derivatives | |
| JPS51113890A (en) | Method for preparing novel cephalosporins | |
| ES385834A1 (en) | [NOVEL] ESTERS OF alpha-CARBOXYBENZYLPENCILLIN | |
| ES413744A1 (en) | A procedure for the preparation of compounds of 1-alpha-hydrazino-beta-fenilproponico acid. (Machine-translation by Google Translate, not legally binding) | |
| ES482419A1 (en) | A procedure for the preparation of eteres of the acid - clavulanic. (Machine-translation by Google Translate, not legally binding) | |
| ES426123A2 (en) | 2-propyl-5-thiazole carboxylates | |
| ES367971A1 (en) | A procedure for the obtaining of i-phenoxy-2-hydroxy-butilaminopropanos etinil-substitute (Machine-translation by Google Translate, not legally binding) | |
| ES241019A2 (en) | Procedure for the obtaining of new derivatives of 3,5-dicetopirazolidina (Machine-translation by Google Translate, not legally binding) | |
| ES465515A1 (en) | Procedure for the obtaining of derivatives of acids 3,3'triaril-metanodicarboxilicos. (Machine-translation by Google Translate, not legally binding) | |
| GB1309993A (en) | Process for the preparation of 2-thion-oxazolidinone-5 and derivativ es thereof | |
| ES453836A1 (en) | Procedure for the preparation of derivatives of 5-sulfamilbenzoico acid substituted with heterociclic radicals. (Machine-translation by Google Translate, not legally binding) |