ES343003A1 - Un procedimiento para la preparacion de un compuesto tetra-hidro-isoquinoleina. - Google Patents
Un procedimiento para la preparacion de un compuesto tetra-hidro-isoquinoleina.Info
- Publication number
- ES343003A1 ES343003A1 ES343003A ES343003A ES343003A1 ES 343003 A1 ES343003 A1 ES 343003A1 ES 343003 A ES343003 A ES 343003A ES 343003 A ES343003 A ES 343003A ES 343003 A1 ES343003 A1 ES 343003A1
- Authority
- ES
- Spain
- Prior art keywords
- dimethoxy
- trimethoxy
- phenyl
- tetrahydro
- dihydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- -1 1-substituted 6,7-dihydroxy-1,2,3,4- tetrahydro-isoquinolines Chemical class 0.000 abstract 6
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 4
- NYYDOYPLJAIRJX-UHFFFAOYSA-N 1-[dimethoxy-(2-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol Chemical compound COC1=C(C(C2NCCC3=CC(=C(C=C23)O)O)(OC)OC)C=CC=C1 NYYDOYPLJAIRJX-UHFFFAOYSA-N 0.000 abstract 2
- FQDMSPFPWVUVKY-UHFFFAOYSA-N 2-(2,3,4-trimethoxyphenyl)acetaldehyde Chemical compound COC1=CC=C(CC=O)C(OC)=C1OC FQDMSPFPWVUVKY-UHFFFAOYSA-N 0.000 abstract 2
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229940124630 bronchodilator Drugs 0.000 abstract 2
- 239000000168 bronchodilator agent Substances 0.000 abstract 2
- 239000000496 cardiotonic agent Substances 0.000 abstract 2
- 125000001891 dimethoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000005805 dimethoxy phenyl group Chemical group 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7582065 | 1965-12-08 | ||
| JP3752466 | 1966-06-09 | ||
| JP4828366 | 1966-07-22 | ||
| JP4828266 | 1966-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES343003A1 true ES343003A1 (es) | 1968-08-16 |
Family
ID=27460434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES343003A Expired ES343003A1 (es) | 1965-12-08 | 1967-07-13 | Un procedimiento para la preparacion de un compuesto tetra-hidro-isoquinoleina. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3497516A (en, 2012) |
| AT (1) | AT269882B (en, 2012) |
| BE (1) | BE689865A (en, 2012) |
| CH (1) | CH468384A (en, 2012) |
| DE (1) | DE1620567A1 (en, 2012) |
| DK (1) | DK123031B (en, 2012) |
| ES (1) | ES343003A1 (en, 2012) |
| FI (1) | FI48079C (en, 2012) |
| FR (1) | FR5747M (en, 2012) |
| GB (1) | GB1114660A (en, 2012) |
| IL (1) | IL28215A (en, 2012) |
| MY (1) | MY6900335A (en, 2012) |
| NL (1) | NL6617017A (en, 2012) |
| NO (1) | NO121340B (en, 2012) |
| SE (1) | SE323963B (en, 2012) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3818015A (en) * | 1970-12-17 | 1974-06-18 | Tanabe Seiyaku Co | 1(polymethoxybenzyl) 6 hydroxyl 1,2,3,4 tetrahydro isoquinolines |
| US3846432A (en) * | 1970-12-29 | 1974-11-05 | Fujisawa Pharmaceutical Co | Derivatives of 1,2,3,4-tetrahydroisoquinoline |
| US3963725A (en) * | 1973-07-20 | 1976-06-15 | Fujisawa Pharmaceutical Co., Ltd. | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof |
| BG38182A1 (en) * | 1983-06-21 | 1985-11-15 | Ivanova | Tocolytic means |
| WO1999016752A1 (en) * | 1997-09-30 | 1999-04-08 | Molecular Designs International, Inc. | β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING |
| US6593341B2 (en) | 2001-03-29 | 2003-07-15 | Molecular Design International, Inc. | β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same |
| US6596734B1 (en) | 2002-10-11 | 2003-07-22 | Molecular Design International, Inc. | Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL286505A (en, 2012) * | 1961-12-15 |
-
1966
- 1966-09-15 US US579504A patent/US3497516A/en not_active Expired - Lifetime
- 1966-09-22 FR FR77345A patent/FR5747M/fr not_active Expired
- 1966-09-30 DE DE19661620567 patent/DE1620567A1/de active Pending
- 1966-11-17 BE BE689865D patent/BE689865A/xx not_active IP Right Cessation
- 1966-11-22 NO NO165684A patent/NO121340B/no unknown
- 1966-11-24 SE SE16115/66A patent/SE323963B/xx unknown
- 1966-12-02 NL NL6617017A patent/NL6617017A/xx unknown
- 1966-12-05 GB GB54413/66A patent/GB1114660A/en not_active Expired
- 1966-12-07 DK DK632566AA patent/DK123031B/da not_active IP Right Cessation
- 1966-12-08 CH CH1747666A patent/CH468384A/de unknown
-
1967
- 1967-06-28 IL IL28215A patent/IL28215A/xx unknown
- 1967-07-11 AT AT648267A patent/AT269882B/de active
- 1967-07-13 ES ES343003A patent/ES343003A1/es not_active Expired
- 1967-07-21 FI FI672013A patent/FI48079C/fi active
-
1969
- 1969-12-31 MY MY1969335A patent/MY6900335A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK123031B (da) | 1972-05-08 |
| FI48079C (fi) | 1974-06-10 |
| MY6900335A (en) | 1969-12-31 |
| GB1114660A (en) | 1968-05-22 |
| NL6617017A (en, 2012) | 1967-06-09 |
| US3497516A (en) | 1970-02-24 |
| FI48079B (en, 2012) | 1974-02-28 |
| DE1620567A1 (de) | 1970-04-30 |
| BE689865A (en, 2012) | 1967-05-02 |
| IL28215A (en) | 1971-02-25 |
| FR5747M (en, 2012) | 1968-01-29 |
| CH468384A (de) | 1969-02-15 |
| AT269882B (de) | 1969-04-10 |
| NO121340B (en, 2012) | 1971-02-15 |
| SE323963B (en, 2012) | 1970-05-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19880222 |