ES342500A1 - Procedimiento de preparacion de los nuevos derivados de la piperonil-piperacina. - Google Patents
Procedimiento de preparacion de los nuevos derivados de la piperonil-piperacina.Info
- Publication number
- ES342500A1 ES342500A1 ES342500A ES342500A ES342500A1 ES 342500 A1 ES342500 A1 ES 342500A1 ES 342500 A ES342500 A ES 342500A ES 342500 A ES342500 A ES 342500A ES 342500 A1 ES342500 A1 ES 342500A1
- Authority
- ES
- Spain
- Prior art keywords
- piperonyl
- choh
- general formula
- formula
- piperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NBOOZXVYXHATOW-UHFFFAOYSA-N 1-(1,3-benzodioxol-5-ylmethyl)piperazine Chemical class C=1C=C2OCOC2=CC=1CN1CCNCC1 NBOOZXVYXHATOW-UHFFFAOYSA-N 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- -1 aroylalkyl chloride Chemical compound 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- KRIOVPPHQSLHCZ-UHFFFAOYSA-N propiophenone Chemical compound CCC(=O)C1=CC=CC=C1 KRIOVPPHQSLHCZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003944 tolyl group Chemical group 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
- 125000005023 xylyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR67675A FR1485246A (fr) | 1966-06-30 | 1966-06-30 | Nouveaux dérivés de la piperonyl-piperazine et leur procédé de préparation |
| FR77964A FR6226M (2) | 1966-06-30 | 1966-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES342500A1 true ES342500A1 (es) | 1968-07-16 |
Family
ID=26171694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES342500A Expired ES342500A1 (es) | 1966-06-30 | 1967-06-30 | Procedimiento de preparacion de los nuevos derivados de la piperonil-piperacina. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3523120A (2) |
| BE (1) | BE700295A (2) |
| CH (1) | CH475279A (2) |
| DE (1) | DE1695736A1 (2) |
| ES (1) | ES342500A1 (2) |
| FR (2) | FR1485246A (2) |
| GB (1) | GB1151971A (2) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2604838A1 (de) * | 1976-02-07 | 1977-08-11 | Knoll Ag | Alkylendioxypiperazinderivate |
| US4268512A (en) * | 1976-08-04 | 1981-05-19 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation |
| IT1156990B (it) * | 1978-04-27 | 1987-02-04 | Geymonat Sud Spa | Procedimento per la preparazione del cloridrato di p clorofenossiacetil piperonilpierazina |
| FR2527605A1 (fr) * | 1982-05-25 | 1983-12-02 | Fordonal Sa | Derives de piperazine, procede de fabrication et medicaments en resultant |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1473829A (fr) * | 1964-06-09 | 1967-03-24 | Ile De France | Nu-(tertiaire-aminoalkyl)-méthylène dioxybenzamides et leur préparation |
| US3362956A (en) * | 1965-08-19 | 1968-01-09 | Sterling Drug Inc | 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines |
| US3422120A (en) * | 1966-05-10 | 1969-01-14 | Upjohn Co | 1,1 - bis(3,4 - methylenedioxyphenyl)-2-methyl-3-(tert-amino)propanols and derivatives thereof |
-
1966
- 1966-06-30 FR FR67675A patent/FR1485246A/fr not_active Expired
- 1966-09-28 FR FR77964A patent/FR6226M/fr not_active Expired
-
1967
- 1967-06-07 US US644059A patent/US3523120A/en not_active Expired - Lifetime
- 1967-06-14 DE DE19671695736 patent/DE1695736A1/de active Pending
- 1967-06-21 BE BE700295D patent/BE700295A/xx unknown
- 1967-06-29 GB GB30012/67A patent/GB1151971A/en not_active Expired
- 1967-06-29 CH CH924367A patent/CH475279A/fr not_active IP Right Cessation
- 1967-06-30 ES ES342500A patent/ES342500A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH475279A (fr) | 1969-07-15 |
| GB1151971A (en) | 1969-05-14 |
| FR6226M (2) | 1968-08-05 |
| DE1695736A1 (de) | 1972-03-02 |
| BE700295A (2) | 1967-12-21 |
| FR1485246A (fr) | 1967-06-16 |
| US3523120A (en) | 1970-08-04 |
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