ES342062A1 - Procedimiento para la produccion de 1-fenil-2-aminoetano. - Google Patents
Procedimiento para la produccion de 1-fenil-2-aminoetano.Info
- Publication number
- ES342062A1 ES342062A1 ES342062A ES342062A ES342062A1 ES 342062 A1 ES342062 A1 ES 342062A1 ES 342062 A ES342062 A ES 342062A ES 342062 A ES342062 A ES 342062A ES 342062 A1 ES342062 A1 ES 342062A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- alkyl
- chlorophenyl
- compounds
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- -1 1-(p-chlorophenyl)-2- formylamino - butane 1 - (p - chlorophenyl)- butanone Chemical compound 0.000 abstract 3
- JSZOAYXJRCEYSX-UHFFFAOYSA-N 1-nitropropane Chemical compound CCC[N+]([O-])=O JSZOAYXJRCEYSX-UHFFFAOYSA-N 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- IOAJWDUHRZDCAJ-UHFFFAOYSA-N 1,2-dichloro-4-(2-nitrobut-1-enyl)benzene Chemical compound CCC([N+]([O-])=O)=CC1=CC=C(Cl)C(Cl)=C1 IOAJWDUHRZDCAJ-UHFFFAOYSA-N 0.000 abstract 1
- SOBINWSGYXRJND-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-(methylamino)pent-1-en-1-ol Chemical compound ClC1=CC=C(C=C1)C(=C(CCC)NC)O SOBINWSGYXRJND-UHFFFAOYSA-N 0.000 abstract 1
- HAELFEDVTLKJMU-UHFFFAOYSA-N 1-(4-chlorophenyl)butan-1-ol Chemical compound CCCC(O)C1=CC=C(Cl)C=C1 HAELFEDVTLKJMU-UHFFFAOYSA-N 0.000 abstract 1
- JQZAEUFPPSRDOP-UHFFFAOYSA-N 1-chloro-4-(chloromethyl)benzene Chemical group ClCC1=CC=C(Cl)C=C1 JQZAEUFPPSRDOP-UHFFFAOYSA-N 0.000 abstract 1
- QNZGBKFZLKIUPN-UHFFFAOYSA-N 2-[(4-chlorophenyl)methyl]propanedioic acid Chemical compound OC(=O)C(C(O)=O)CC1=CC=C(Cl)C=C1 QNZGBKFZLKIUPN-UHFFFAOYSA-N 0.000 abstract 1
- DMIIFTRCIMNYKZ-UHFFFAOYSA-N 2-[1-(4-chlorophenyl)butan-2-yl]isoindole-1,3-dione Chemical compound ClC1=CC=C(C=C1)CC(CC)N1C(C=2C(C1=O)=CC=CC2)=O DMIIFTRCIMNYKZ-UHFFFAOYSA-N 0.000 abstract 1
- KMGUEILFFWDGFV-UHFFFAOYSA-N 2-benzoyl-2-benzoyloxy-3-hydroxybutanedioic acid Chemical compound C=1C=CC=CC=1C(=O)C(C(C(O)=O)O)(C(O)=O)OC(=O)C1=CC=CC=C1 KMGUEILFFWDGFV-UHFFFAOYSA-N 0.000 abstract 1
- MJFYJSUVLVMOOX-UHFFFAOYSA-N 2-benzyl-1-(4-chlorophenyl)-2-(methylamino)pentan-1-one Chemical compound ClC1=CC=C(C=C1)C(C(CCC)(CC1=CC=CC=C1)NC)=O MJFYJSUVLVMOOX-UHFFFAOYSA-N 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- AVPYQKSLYISFPO-UHFFFAOYSA-N 4-chlorobenzaldehyde Chemical compound ClC1=CC=C(C=O)C=C1 AVPYQKSLYISFPO-UHFFFAOYSA-N 0.000 abstract 1
- UOQXIWFBQSVDPP-UHFFFAOYSA-N 4-fluorobenzaldehyde Chemical compound FC1=CC=C(C=O)C=C1 UOQXIWFBQSVDPP-UHFFFAOYSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- BDAGIHXWWSANSR-UHFFFAOYSA-M Formate Chemical compound [O-]C=O BDAGIHXWWSANSR-UHFFFAOYSA-M 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N Methyl ethyl ketone Natural products CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- LRVYGDGSWJYKNH-UHFFFAOYSA-N bromoethane 3-[1-(4-chlorophenyl)propoxy]-3-oxopropanoic acid Chemical compound C(CC(=O)O)(=O)OC(C1=CC=C(C=C1)Cl)CC.C(C)Br LRVYGDGSWJYKNH-UHFFFAOYSA-N 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000005660 chlorination reaction Methods 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- RIWRFSMVIUAEBX-UHFFFAOYSA-N n-methyl-1-phenylmethanamine Chemical compound CNCC1=CC=CC=C1 RIWRFSMVIUAEBX-UHFFFAOYSA-N 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0087689 | 1966-06-23 | ||
| DEB0088652 | 1966-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES342062A1 true ES342062A1 (es) | 1968-07-16 |
Family
ID=25967949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES342062A Expired ES342062A1 (es) | 1966-06-23 | 1967-06-20 | Procedimiento para la produccion de 1-fenil-2-aminoetano. |
Country Status (6)
| Country | Link |
|---|---|
| AT (1) | AT286259B (en, 2012) |
| BE (1) | BE700459A (en, 2012) |
| ES (1) | ES342062A1 (en, 2012) |
| FR (1) | FR7510M (en, 2012) |
| GB (1) | GB1192223A (en, 2012) |
| NL (1) | NL6708305A (en, 2012) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2239012A1 (de) * | 1972-08-08 | 1974-02-21 | Knoll Ag | Basisch substituierte theophyllinabkoemmlinge |
-
1967
- 1967-06-15 NL NL6708305A patent/NL6708305A/xx unknown
- 1967-06-20 ES ES342062A patent/ES342062A1/es not_active Expired
- 1967-06-23 BE BE700459D patent/BE700459A/xx unknown
- 1967-06-23 GB GB29217/67A patent/GB1192223A/en not_active Expired
- 1967-06-23 AT AT589167A patent/AT286259B/de not_active IP Right Cessation
- 1967-09-22 FR FR121987A patent/FR7510M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE700459A (en, 2012) | 1967-12-27 |
| GB1192223A (en) | 1970-05-20 |
| FR7510M (en, 2012) | 1969-12-15 |
| NL6708305A (en, 2012) | 1967-12-27 |
| AT286259B (de) | 1970-12-10 |
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