ES333366A1 - Procedimiento para producir 7-cloro-6-demetiltetraciclina. - Google Patents
Procedimiento para producir 7-cloro-6-demetiltetraciclina.Info
- Publication number
- ES333366A1 ES333366A1 ES333366A ES333366A ES333366A1 ES 333366 A1 ES333366 A1 ES 333366A1 ES 333366 A ES333366 A ES 333366A ES 333366 A ES333366 A ES 333366A ES 333366 A1 ES333366 A1 ES 333366A1
- Authority
- ES
- Spain
- Prior art keywords
- nrrl
- chloro
- reflectance
- point
- demethyltetracycline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FMTDIUIBLCQGJB-UHFFFAOYSA-N Demethylchlortetracyclin Natural products C1C2C(O)C3=C(Cl)C=CC(O)=C3C(=O)C2=C(O)C2(O)C1C(N(C)C)C(O)=C(C(N)=O)C2=O FMTDIUIBLCQGJB-UHFFFAOYSA-N 0.000 title abstract 4
- FMTDIUIBLCQGJB-SEYHBJAFSA-N demeclocycline Chemical compound C1([C@@H](O)[C@H]2C3)=C(Cl)C=CC(O)=C1C(=O)C2=C(O)[C@@]1(O)[C@@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FMTDIUIBLCQGJB-SEYHBJAFSA-N 0.000 title abstract 4
- 230000004151 fermentation Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000186984 Kitasatospora aureofaciens Species 0.000 abstract 2
- RMVMLZHPWMTQGK-SOUFLCLCSA-N (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1([C@H]2O)=CC=CC(O)=C1C(O)=C1[C@@H]2C[C@H]2[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]2(O)C1=O RMVMLZHPWMTQGK-SOUFLCLCSA-N 0.000 abstract 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 1
- JCSGAUKCDAVARS-UHFFFAOYSA-N demethyltetracycline Natural products CN(C1C(=C(C(C2(C(=C3C(C4=C(C=CC=C4C(C3CC12)O)O)=O)O)O)=O)C(=O)N)O)C JCSGAUKCDAVARS-UHFFFAOYSA-N 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000219 mutagenic Toxicity 0.000 abstract 1
- 230000003505 mutagenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/485—Streptomyces aureofaciens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA945388 | 1965-11-15 | ||
| CA970545 | 1966-09-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES333366A1 true ES333366A1 (es) | 1968-03-16 |
Family
ID=25673596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES333366A Expired ES333366A1 (es) | 1965-11-15 | 1966-11-15 | Procedimiento para producir 7-cloro-6-demetiltetraciclina. |
Country Status (15)
| Country | Link |
|---|---|
| BE (1) | BE689013A (OSRAM) |
| BR (1) | BR6684265D0 (OSRAM) |
| CH (2) | CH492019A (OSRAM) |
| DE (1) | DE1617281A1 (OSRAM) |
| DK (1) | DK113983B (OSRAM) |
| ES (1) | ES333366A1 (OSRAM) |
| FI (1) | FI43721C (OSRAM) |
| FR (1) | FR1504086A (OSRAM) |
| GB (1) | GB1166681A (OSRAM) |
| IL (1) | IL26762A (OSRAM) |
| LU (1) | LU52319A1 (OSRAM) |
| MC (1) | MC623A1 (OSRAM) |
| NL (1) | NL6616081A (OSRAM) |
| NO (1) | NO123470B (OSRAM) |
| SE (1) | SE346564B (OSRAM) |
-
1966
- 1966-10-24 NO NO165323A patent/NO123470B/no unknown
- 1966-10-26 IL IL26762A patent/IL26762A/xx unknown
- 1966-10-28 BE BE689013D patent/BE689013A/xx unknown
- 1966-10-31 GB GB48781/66A patent/GB1166681A/en not_active Expired
- 1966-11-03 BR BR184265/66A patent/BR6684265D0/pt unknown
- 1966-11-08 LU LU52319D patent/LU52319A1/xx unknown
- 1966-11-10 FI FI662970A patent/FI43721C/fi active
- 1966-11-10 FR FR83332A patent/FR1504086A/fr not_active Expired
- 1966-11-14 CH CH1632266A patent/CH492019A/fr not_active IP Right Cessation
- 1966-11-14 CH CH303270A patent/CH501727A/fr not_active IP Right Cessation
- 1966-11-14 DK DK589866AA patent/DK113983B/da unknown
- 1966-11-15 ES ES333366A patent/ES333366A1/es not_active Expired
- 1966-11-15 DE DE19661617281 patent/DE1617281A1/de active Pending
- 1966-11-15 MC MC655A patent/MC623A1/xx unknown
- 1966-11-15 NL NL6616081A patent/NL6616081A/xx unknown
- 1966-11-15 SE SE15604/66A patent/SE346564B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK113983B (da) | 1969-05-19 |
| FR1504086A (fr) | 1967-12-01 |
| LU52319A1 (OSRAM) | 1967-01-09 |
| IL26762A (en) | 1970-04-20 |
| MC623A1 (fr) | 1967-07-04 |
| SE346564B (OSRAM) | 1972-07-10 |
| CH492019A (fr) | 1970-06-15 |
| CH501727A (fr) | 1971-01-15 |
| GB1166681A (en) | 1969-10-08 |
| BE689013A (OSRAM) | 1967-04-28 |
| FI43721B (OSRAM) | 1971-03-01 |
| FI43721C (fi) | 1971-06-10 |
| NL6616081A (OSRAM) | 1967-05-16 |
| NO123470B (OSRAM) | 1971-11-22 |
| DE1617281A1 (de) | 1971-04-08 |
| BR6684265D0 (pt) | 1973-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19871214 |