ES319190A1 - Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES319190A1
ES319190A1 ES0319190A ES319190A ES319190A1 ES 319190 A1 ES319190 A1 ES 319190A1 ES 0319190 A ES0319190 A ES 0319190A ES 319190 A ES319190 A ES 319190A ES 319190 A1 ES319190 A1 ES 319190A1
Authority
ES
Spain
Prior art keywords
formula
lower alkyl
translation
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0319190A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1431564A external-priority patent/CH442299A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES319190A1 publication Critical patent/ES319190A1/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for obtaining heterocyclic guanidine derivatives of formula I ** (See formula) ** where one of the radicals R1 and R2 means hydrogen or lower alkyl and the other lower alkyl, where R1 and R2, on the same carbon atom, may contain a total of at most 2 carbon atoms, R3 and R4 each meaning hydrogen or methyl and Y represents a direct bond and Z a radical NH2 or Y a radical NH and Z hydrogen, and their acid addition salts, characterized in that a hydrazine derivative of formula II ** (See formula) ** where R1 and R2 have the meaning above, is reacted with a compound of formula III ** (See formula) ** where R 4 has the meaning indicated above and either R 3 agrees with R 3 of the definition above and Z means an alkylthio residue or a 1-pyrazolyl radical mono- or di-substituted by lower alkyl or aryl, or Z and R'3 together form a third bond between the carbon atom and the nitrogen atom, in the presence of an equivalent of an acid, the base obtained is released from the salt obtained and, if desired, it is treated with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES0319190A 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding) Expired ES319190A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1431564A CH442299A (en) 1964-11-05 1964-11-05 Process for the preparation of new heterocyclic guanidine derivatives
CH1254265 1965-09-08

Publications (1)

Publication Number Publication Date
ES319190A1 true ES319190A1 (en) 1966-04-16

Family

ID=25710450

Family Applications (2)

Application Number Title Priority Date Filing Date
ES0319192A Expired ES319192A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)
ES0319190A Expired ES319190A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES0319192A Expired ES319192A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
AT (1) AT258952B (en)
ES (2) ES319192A1 (en)

Also Published As

Publication number Publication date
AT258952B (en) 1967-12-27
ES319192A1 (en) 1966-05-01

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