ES319189A1 - Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES319189A1
ES319189A1 ES0319189A ES319189A ES319189A1 ES 319189 A1 ES319189 A1 ES 319189A1 ES 0319189 A ES0319189 A ES 0319189A ES 319189 A ES319189 A ES 319189A ES 319189 A1 ES319189 A1 ES 319189A1
Authority
ES
Spain
Prior art keywords
formula
translation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0319189A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1431564A external-priority patent/CH442299A/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES319189A1 publication Critical patent/ES319189A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for obtaining heterocyclic guanidine derivatives of the formula: ** (See formula) ** where R1 and R2 each mean lower alkyl, R3 and R4 each time hydrogen or methyl and, either Y means a direct bond and Z a radical NH2 or Y means a radical NH and Z hydrogen, and their acid addition salts , characterized in that a hydrazine derivative of formula ** (See formula) ** where R1 and R2 have the meaning above, is reacted with a compound of formula: ** (See formula) ** where R 4 has the meaning indicated above and either R 3 agrees with R 3 of the definition above and Z means an alkylthio residue or a 1-pyrazolyl radical mono- or di-substituted by lower alkyl or aryl, or Z and R'3 together form a third bond between the carbon atom and the nitrogen atom, in the presence of an equivalent of an acid, the base obtained is released from the salt obtained and, if desired, is treated with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
ES0319189A 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding) Expired ES319189A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1431564A CH442299A (en) 1964-11-05 1964-11-05 Process for the preparation of new heterocyclic guanidine derivatives
CH1254165 1965-09-08

Publications (1)

Publication Number Publication Date
ES319189A1 true ES319189A1 (en) 1966-07-01

Family

ID=25710447

Family Applications (2)

Application Number Title Priority Date Filing Date
ES0319189A Expired ES319189A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)
ES0319191A Expired ES319191A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES0319191A Expired ES319191A1 (en) 1964-11-05 1965-11-03 Procedure for the obtaining of heterociclic derivatives of guanidine. (Machine-translation by Google Translate, not legally binding)

Country Status (3)

Country Link
AT (1) AT258951B (en)
ES (2) ES319189A1 (en)
OA (1) OA01851A (en)

Also Published As

Publication number Publication date
ES319191A1 (en) 1966-08-01
AT258951B (en) 1967-12-27
OA01851A (en) 1970-01-14

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