ES319079A1 - Procedure for the manufacture of basically replaced ureas ciclicas and their salts. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the manufacture of basically replaced ureas ciclicas and their salts. (Machine-translation by Google Translate, not legally binding)
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Asta Medica GmbH
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Asta Werke AG Chemische Fabrik
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Priority to ES0319079ApriorityCriticalpatent/ES319079A1/en
Publication of ES319079A1publicationCriticalpatent/ES319079A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
Process for the production of basically substituted cyclic ureas and their salts of the general formula I ** (See formula) ** wherein R1 is a saturated or unsaturated aliphatic hydrocarbon residue with 12 to 18 carbon atoms and n number 2 or 3, and R2 and R3 represent lower alkyl moieties or together with the nitrogen atom, with which they are combined, piperidino, morpholino or pyrrolidino groups, characterized in that a cyclic urea of the general formula II is reacted ** (See formula) ** wherein X is a halogen atom, and R1 and n have the same meaning as in formula I, with a secondary amine of the general formula III ** (See formula) ** wherein R2 and R3 have the same meaning as in formula I, at high temperature in the presence of an acid-binding compound, and the substantially substituted cyclic urea obtained is optionally transferred to the salt state. (Machine-translation by Google Translate, not legally binding)
ES0319079A1965-10-291965-10-29Procedure for the manufacture of basically replaced ureas ciclicas and their salts. (Machine-translation by Google Translate, not legally binding)
ExpiredES319079A1
(en)
Procedure for preparing N-alcohilamino-alcohilic derivatives of espirotetralinosuccinimidas and their salts. (Machine-translation by Google Translate, not legally binding)
A method to produce new derivatives of indolilalcohil guanidine and salts from themselves (Machine-translation by Google Translate, not legally binding)