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Novartis AG
BASF Schweiz AG
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Ciba Geigy AG
Ciba AG
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Application filed by Ciba Geigy AG, Ciba AGfiledCriticalCiba Geigy AG
Publication of ES289308A1publicationCriticalpatent/ES289308A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for obtaining guanidine compounds of formula ** (See formula) ** where R means aryl and each of the groups R1, R2, R3, R4 and R5 signify hydrogen or lower alkyl, and their acid-editing seles, characterized, because according to known methods, in the amines of formula ** (See formula) ** where each of the groups R, R1, R2 and R3 have the meaning indicated above and RX is hydrogen or a transformable moiety in an amidinic group of formula ** (See formula) ** where R4 and R5 have the meaning indicated above, or in their salts, the group of the formula -NH-RX is transformed into a guanidino group of formula ** (See formula) ** where R4 and R5 have the meaning of above or in the compounds of formula ** (See formula) ** where R, R1, R2, R4 and R5 have the meaning indicated above and X is oxygen or sulfur, or in their salts, the group X is replaced by two hydrogen atoms and, if desired, the salts obtained are transformed into the free compounds and/or if desired, the free compounds are transformed into their salts. (Machine-translation by Google Translate, not legally binding)
ES289308A1962-06-251963-06-24Procedure for the obtaining of guanidine compounds (Machine-translation by Google Translate, not legally binding)
ExpiredES289308A1
(en)
A method to produce new derivatives of indolilalcohil guanidine and salts from themselves (Machine-translation by Google Translate, not legally binding)