ES293384A1 - A procedure for preparing derivatives of colchicine and tiocolchicine (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing derivatives of colchicine and tiocolchicine (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES293384A1
ES293384A1 ES0293384A ES293384A ES293384A1 ES 293384 A1 ES293384 A1 ES 293384A1 ES 0293384 A ES0293384 A ES 0293384A ES 293384 A ES293384 A ES 293384A ES 293384 A1 ES293384 A1 ES 293384A1
Authority
ES
Spain
Prior art keywords
colchicine
translation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0293384A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES293384A1 publication Critical patent/ES293384A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N45/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring
    • A01N45/02—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds having three or more carbocyclic rings condensed among themselves, at least one ring not being a six-membered ring having three carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparation of colchicine and thiocolchicine derivatives of the general formula: ** (See formula) ** in which Y represents hydrogen or a radical (see formula) R1 and R2, which are the same or different, represent hydrogen, a lower alkyl radical, aryl or aralkyl, represents hydrogen or an acyl radical, and Z a -O-alkyl, or an -S-alkyl, and their salts of quaternary ammonium, and among these compounds especially 1-dimethyl-aminomethyl-2-demethylcolchicine and its salts, such as methoiodide and 1-dimethyl-aminomethyl-2-demethylthiocolchicine and their salts, such as methoiodide, characterized in that it is react with formaldehyde, in the presence of ammonia or a primary amine or secondary derivative of colchicine or thiocolchicine of the general formula: ** (See formula) ** conserving Y and Z the cited meanings, the derivative is obtained (see formula) corresponding, and it is transformed, if necessary, into quaternary ammonium salt or a corresponding 2-acylated compound. (Machine-translation by Google Translate, not legally binding)
ES0293384A 1962-11-12 1963-11-11 A procedure for preparing derivatives of colchicine and tiocolchicine (Machine-translation by Google Translate, not legally binding) Expired ES293384A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR915142A FR1347137A (en) 1962-11-12 1962-11-12 New derivatives of colchicine and thiocolchicine and method of preparation

Publications (1)

Publication Number Publication Date
ES293384A1 true ES293384A1 (en) 1964-01-01

Family

ID=8790618

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0293384A Expired ES293384A1 (en) 1962-11-12 1963-11-11 A procedure for preparing derivatives of colchicine and tiocolchicine (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
AT (1) AT241031B (en)
CH (1) CH444144A (en)
ES (1) ES293384A1 (en)
FR (1) FR1347137A (en)

Also Published As

Publication number Publication date
CH444144A (en) 1967-09-30
FR1347137A (en) 1963-12-27
AT241031B (en) 1965-06-25

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