ES304850A1 - Procedure for the obtaining of new aminohalogeno-bencilaminas. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of new aminohalogeno-bencilaminas. (Machine-translation by Google Translate, not legally binding)
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Boehringer Ingelheim Pharma GmbH and Co KG
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Dr Karl Thomae GmbH
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Publication of ES304850A1publicationCriticalpatent/ES304850A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Hydrogenated Pyridines
(AREA)
Abstract
Procedure for obtaining new amino-halogenobenzylamines of the formula ** (See formula) ** wherein X represents chlorine or bromine and Y is the free amino group, or X is the free amino group and Y is chlorine or bromine, and R and R ', which may be the same or different, represent lower straight or branched alkyl groups, saturated or unsaturated, cycloalkyl, aralkyl or aryl radicals, or, together with the nitrogen atom, a pyrrolidine or piperidine ring, optionally comprising lower alkyl radicals as well as their acid addition salts with physiologically tolerable inorganic or organic acids, characterized by the fact that, by usual procedures: a) halogen-nitro-benzylamines of the formula are reduced ** (See formula) ** where Z represents chlorine or bromine and A the nitro group or Z the nitro group and A chlorine or bromine, and R and R 'have the meanings mentioned in principle, or b) mono- or diacylamino-halogen-benzyl-halides of the formula are transformed ** (See formula) ** where B chlorine or bromine and C represent the rest (see formula) representing ac any acyl residue and R "a hydrogen atom or any acyl residue, or B represents the remainder (see formula) and C chlorine or bromine, and Hal chlorine or bromine, with amines of the formula ** (See formula) ** where R and R 'have the meanings indicated above, in the presence of a fixing medium of halogen hydrocides, and then the acyl residues are dissociated, or c) amino-halogen-benzamide complexes of the formula are reduced by metal hydrides where X, Y, R and R 'have the meanings mentioned above, and the compounds thus obtained are converted, optionally in known manner, into their acid addition salts, with physiologically tolerable inorganic or organic acids. (Machine-translation by Google Translate, not legally binding)
ES0304850A1963-10-141964-10-10Procedure for the obtaining of new aminohalogeno-bencilaminas. (Machine-translation by Google Translate, not legally binding)
ExpiredES304850A1
(en)
Procedure for the preparation of new compounds of 1,4-benzodioxane and 1,5-benzodioxepane (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of derivatives of the ftalimiento for the obtaining of ftalimidina (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of amidas of N-alkyl piperidin monocarboxylic acid and N-alkyl pirrolidin alpha-monocarboxylic acid (Machine-translation by Google Translate, not legally binding)