Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
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Publication date
Application filed by Dr Karl Thomae GmbHfiledCriticalDr Karl Thomae GmbH
Priority to ES0267278ApriorityCriticalpatent/ES267278A2/en
Publication of ES267278A2publicationCriticalpatent/ES267278A2/en
Improvements in the object of the main patent No. 256.603, by: Process for obtaining substituted carbinols basically of the general formula ** (See formula) ** where R1 represents a low molecular weight alkyl radical, hydrogen R2, a low molecular weight alkyl radical, an optionally substituted aryl or aralkyl radical, R3 and R4 which may be the same or different, represent hydrogen, an alkyl or lower alkoxy radical molecular weight, halogen or a tertiary amino group, R5 and R6, which may be the same or different, represent hydrogen or a low molecular weight alkyl radical, wherein R5 and R6 may also together with the nitrogen atom, form a pyrrolidine ring or piperidine, and where n represents the number 1 or 2, as well as its acid addition salts, characterized in that a beta-halogenocarbinol of the formula is transformed ** (See formula) ** where R1, R2 and n have the meaning, previously indicated and Hal represents a halogen atom, with an amine of the formula ** (See formula) ** wherein R 5 and R 6 have the meaning indicated above, in the presence of an antacid medium, optionally in an inert solvent and optionally under pressure, at increased temperatures, and preferably at temperatures of more than 100º C. (Machine-translation by Google Translate, not legally binding)
ES0267278A1961-05-091961-05-09Procedure for obtaining carbinols replaced basically (Machine-translation by Google Translate, not legally binding)
ExpiredES267278A2
(en)
Procedure for the preparation of new compounds of 1,4-benzodioxane and 1,5-benzodioxepane (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of acil-anylides with basic substitutors and their derivatives (Machine-translation by Google Translate, not legally binding)
A procedure for manufacturing amidas of N-alkyl piperidin monocarboxylic acid and N-alkyl pirrolidin alpha-monocarboxylic acid (Machine-translation by Google Translate, not legally binding)