Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH6387458Aexternal-prioritypatent/CH368802A/en
Priority claimed from CH6842559Aexternal-prioritypatent/CH375712A/en
Application filed by Sandoz AGfiledCriticalSandoz AG
Publication of ES251429A1publicationCriticalpatent/ES251429A1/en
C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
C07D209/04—Indoles; Hydrogenated indoles
C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
C07D209/16—Tryptamines
Landscapes
Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Plural Heterocyclic Compounds
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for obtaining new indole derivatives of the general formula I ** (See formula) ** where R1 and R2, meaning identical or different alkyl groups with 1 to 4 carbon atoms or together with the nitrogen atom, a piperidine ring, characterized in that a substituted indole of the general formula II ** (See formula) ** where X means a further cleavable protection group, it is reacted with a dihalide of the oxalic acid and then with an amine of the general formula III ** (See formula) ** where R1 and R2 have the same meaning as above, the reaction product is reduced and the protected group is dissociated according to known methods. (Machine-translation by Google Translate, not legally binding)
ES0251429A1958-09-121959-08-13Procedure for obtaining new indol derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES251429A1
(en)
Procedure for the preparation of new compounds of 1,4-benzodioxane and 1,5-benzodioxepane (Machine-translation by Google Translate, not legally binding)
A procedure for manufacturing amidas of N-alkyl piperidin monocarboxylic acid and N-alkyl pirrolidin alpha-monocarboxylic acid (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of acil-anylides with basic substitutors and their derivatives (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of amidas of N-alkyl piperidin monocarboxylic acid and N-alkyl pirrolidin alpha-monocarboxylic acid (Machine-translation by Google Translate, not legally binding)