ES3041684T3 - Antibody to hepatitis b surface antigen and use thereof - Google Patents

Antibody to hepatitis b surface antigen and use thereof

Info

Publication number
ES3041684T3
ES3041684T3 ES16853117T ES16853117T ES3041684T3 ES 3041684 T3 ES3041684 T3 ES 3041684T3 ES 16853117 T ES16853117 T ES 16853117T ES 16853117 T ES16853117 T ES 16853117T ES 3041684 T3 ES3041684 T3 ES 3041684T3
Authority
ES
Spain
Prior art keywords
seq
presented
antibody
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16853117T
Other languages
English (en)
Spanish (es)
Inventor
Wenxin Luo
Bing Zhou
Juan Zhang
Quan Yuan
Tianying Zhang
Jun Zhang
Ningshao Xia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yang Sheng Tang Co Ltd
Xiamen University
Original Assignee
Yang Sheng Tang Co Ltd
Xiamen University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yang Sheng Tang Co Ltd, Xiamen University filed Critical Yang Sheng Tang Co Ltd
Application granted granted Critical
Publication of ES3041684T3 publication Critical patent/ES3041684T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082Hepadnaviridae, e.g. hepatitis B virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES16853117T 2015-10-09 2016-10-09 Antibody to hepatitis b surface antigen and use thereof Active ES3041684T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510647977 2015-10-09
PCT/CN2016/101560 WO2017059813A1 (zh) 2015-10-09 2016-10-09 抗乙肝表面抗原的抗体及其用途

Publications (1)

Publication Number Publication Date
ES3041684T3 true ES3041684T3 (en) 2025-11-13

Family

ID=58487306

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16853117T Active ES3041684T3 (en) 2015-10-09 2016-10-09 Antibody to hepatitis b surface antigen and use thereof

Country Status (10)

Country Link
US (1) US10689434B2 (enExample)
EP (1) EP3360896B1 (enExample)
JP (2) JP6949012B2 (enExample)
KR (1) KR102132604B1 (enExample)
CN (1) CN106565840B (enExample)
AU (1) AU2016334290B2 (enExample)
BR (1) BR112018007121A2 (enExample)
CA (1) CA3001231C (enExample)
ES (1) ES3041684T3 (enExample)
WO (1) WO2017059813A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3001231C (en) * 2015-10-09 2022-07-12 Xiamen University Antibody against hepatitis b surface antigen and use thereof
US11932681B2 (en) 2018-05-31 2024-03-19 Novartis Ag Hepatitis B antibodies
NZ770866A (en) * 2018-05-31 2025-07-25 Daiichi Sankyo Co Ltd Anti-human tlr7 antibody
JP7454855B2 (ja) * 2018-12-21 2024-03-25 国立大学法人広島大学 抗preS1抗体およびその用途
WO2020233695A1 (zh) * 2019-05-23 2020-11-26 厦门大学 抗乙肝病毒新型抗体及其用途
CN111242107B (zh) * 2020-04-26 2021-03-09 北京外号信息技术有限公司 用于设置空间中的虚拟对象的方法和电子设备
WO2024148263A1 (en) * 2023-01-06 2024-07-11 Victorian Infectious Diseases Reference Laboratory Methods and compositions for antibody treatment of hepatitis b infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1322761A4 (en) 2000-10-02 2005-03-23 Korea Res Inst Of Bioscience HUMANIZED ANTIBODY AGAINST THE HEPATITE B VIRUS SURFACE ANTIGEN AND METHOD OF PREPARING THE SAME
CN1560081A (zh) * 2004-02-17 2005-01-05 大连帝恩生物工程有限公司 用能产生人IgGl重链-κ轻链小鼠作为制备人源化单克隆抗体和应用
US9567390B2 (en) * 2008-01-23 2017-02-14 Department Of Biotechnology Humanized high affinity recombinant antibody against Hepatitis B surface antigen
KR101072895B1 (ko) * 2009-12-24 2011-10-17 주식회사 녹십자 B형 간염 바이러스 표면 항원에 특이적으로 결합하는 인간 항체
CN102786592A (zh) * 2011-05-17 2012-11-21 傅阳心 Hbv特异性抗体
KR102106782B1 (ko) 2012-06-11 2020-05-07 시아먼 유니버시티 에이치비브이 감염 및 관련 질병의 치료를 위한 폴리펩타이드 및 항체
CA2878155C (en) * 2012-07-10 2019-01-08 Green Cross Corporation An antibody composition for prevention or treatment of mutant hepatitis b virus infection
SG10201806025TA (en) * 2014-01-16 2018-08-30 Mario Umberto Francesco Mondelli Neutralizing human monoclonal antibodies against hepatitis b virus surface antigen
CA3001231C (en) * 2015-10-09 2022-07-12 Xiamen University Antibody against hepatitis b surface antigen and use thereof

Also Published As

Publication number Publication date
CA3001231A1 (en) 2017-04-13
WO2017059813A1 (zh) 2017-04-13
JP6949012B2 (ja) 2021-10-13
JP2021063092A (ja) 2021-04-22
AU2016334290A1 (en) 2018-05-10
CN106565840A (zh) 2017-04-19
JP2018533937A (ja) 2018-11-22
CA3001231C (en) 2022-07-12
KR102132604B1 (ko) 2020-07-13
US20190389939A1 (en) 2019-12-26
AU2016334290B2 (en) 2020-06-18
US10689434B2 (en) 2020-06-23
EP3360896A4 (en) 2019-08-28
BR112018007121A2 (pt) 2018-11-06
CN106565840B (zh) 2020-09-01
EP3360896B1 (en) 2025-07-23
EP3360896A1 (en) 2018-08-15
KR20180084045A (ko) 2018-07-24

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