ES2992868T3 - Combination of tim-4 antagonist and pd-1 antagonist and methods of use - Google Patents
Combination of tim-4 antagonist and pd-1 antagonist and methods of use Download PDFInfo
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- ES2992868T3 ES2992868T3 ES17740851T ES17740851T ES2992868T3 ES 2992868 T3 ES2992868 T3 ES 2992868T3 ES 17740851 T ES17740851 T ES 17740851T ES 17740851 T ES17740851 T ES 17740851T ES 2992868 T3 ES2992868 T3 ES 2992868T3
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| WO2021064184A1 (en) * | 2019-10-04 | 2021-04-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer |
| CN110982824B (zh) * | 2019-10-09 | 2022-04-15 | 天津大学 | 拮抗pd-1的抗体类似物bp基因及蛋白和应用 |
| US11774451B2 (en) * | 2019-11-21 | 2023-10-03 | The Board Of Trustees Of The Leland Stanford Junior University | Molecular vibrational spectroscopic markers for detection of cancer |
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| CA3228331A1 (en) * | 2021-08-10 | 2023-02-16 | Karla FRIETZE | Generation and characterization of novel tim-4 binding agents |
| KR20240046882A (ko) | 2021-08-13 | 2024-04-11 | 라픽스 테라퓨틱스, 인코포레이티드 | 면역 불내성의 감소 및 자가면역 장애의 치료를 위한 조성물 및 방법 |
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| WO1991006570A1 (en) | 1989-10-25 | 1991-05-16 | The University Of Melbourne | HYBRID Fc RECEPTOR MOLECULES |
| US5349053A (en) | 1990-06-01 | 1994-09-20 | Protein Design Labs, Inc. | Chimeric ligand/immunoglobulin molecules and their uses |
| KR100246529B1 (ko) | 1990-12-14 | 2000-04-01 | 스티븐 에이. 서윈. 엠.디. | 수용체 관련된 신호 변환 경로를 위한 키메라 사슬 |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| US5447851B1 (en) | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
| NZ292124A (en) | 1994-07-29 | 1998-10-28 | Smithkline Beecham Plc | Il-4 antagonist comprising a fusion of a mutant il-4-antibody fragment |
| TW200539890A (en) * | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| CN101035561A (zh) | 2004-03-24 | 2007-09-12 | 特罗斯药品公司 | 作为改善对疫苗的免疫反应的佐剂的组合物和使用方法 |
| JP4361545B2 (ja) | 2005-05-09 | 2009-11-11 | 小野薬品工業株式会社 | ＰｒｏｇｒａｍｍｅｄＤｅａｔｈ１（ＰＤ−１）に対するヒトモノクローナル抗体および抗ＰＤ−１抗体単独または他の免疫療法と併用した癌治療方法 |
| HRP20151102T1 (xx) | 2005-07-01 | 2015-11-20 | E. R. Squibb & Sons, L.L.C. | Humana monoklonska antitijela za ligand programirane smrti 1 (pd-l1) |
| WO2015048312A1 (en) | 2013-09-26 | 2015-04-02 | Costim Pharmaceuticals Inc. | Methods for treating hematologic cancers |
| JP2015209376A (ja) * | 2014-04-24 | 2015-11-24 | 国立大学法人北海道大学 | 腫瘍特異的免疫増強剤 |
| US11306143B2 (en) | 2016-07-06 | 2022-04-19 | Bristol-Myers Squibb Company | Combination of TIM-4 antagonist and PD-1 antagonist and methods of use |
-
2017
- 2017-07-05 US US16/314,732 patent/US11306143B2/en active Active
- 2017-07-05 CN CN201780054101.9A patent/CN109641968B/zh active Active
- 2017-07-05 EP EP17740851.5A patent/EP3481866B1/en active Active
- 2017-07-05 WO PCT/US2017/040665 patent/WO2018009507A1/en not_active Ceased
- 2017-07-05 ES ES17740851T patent/ES2992868T3/es active Active
- 2017-07-05 KR KR1020197003493A patent/KR102602137B1/ko active Active
- 2017-07-05 JP JP2019500245A patent/JP7164512B2/ja active Active
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2022
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Also Published As
| Publication number | Publication date |
|---|---|
| US20190389950A1 (en) | 2019-12-26 |
| US11306143B2 (en) | 2022-04-19 |
| KR20190026843A (ko) | 2019-03-13 |
| JP7164512B2 (ja) | 2022-11-01 |
| EP3481866B1 (en) | 2024-07-24 |
| US20220275091A1 (en) | 2022-09-01 |
| CN109641968A (zh) | 2019-04-16 |
| JP2019524701A (ja) | 2019-09-05 |
| WO2018009507A1 (en) | 2018-01-11 |
| EP3481866A1 (en) | 2019-05-15 |
| WO2018009507A8 (en) | 2019-02-07 |
| KR102602137B1 (ko) | 2023-11-13 |
| US12227575B2 (en) | 2025-02-18 |
| CN109641968B (zh) | 2023-10-20 |
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