ES299134A1 - Procedure for the preparation of an anti-virus provided composite (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of an anti-virus provided composite (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES299134A1 ES299134A1 ES0299134A ES299134A ES299134A1 ES 299134 A1 ES299134 A1 ES 299134A1 ES 0299134 A ES0299134 A ES 0299134A ES 299134 A ES299134 A ES 299134A ES 299134 A1 ES299134 A1 ES 299134A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- alkyl
- reaction
- halide
- nhr1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/38—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Method of preparing a compound endowed with anti-virus properties, of formula ** (See formula) ** where R is ** (See formula) ** of hydrogen, alkyl of 1 to 6 carbon atoms or alkyl when the alkyl has 1 to 6 carbon atoms and the substituent is hydroxyl, alkoxy of 1 to 2 carbons, -NH2, -NHR3, -NR4R5, where R3 is R2 , chlorine, bromine, formyl, -CH2-COOH, -CH2-COOCH3 or -CH2-COOC2H5; R4 and R5 are, each of them, alkyl of 1 to 4 carbon atoms, X- is a non-toxic anion; salts of said compound and hydrolysable compounds in said compound; Y ** (See formula) ** where R5 and R6 are, each of them, alkyl of 1 to 6 carbons; and where R5 and R6 can be joined together forming the group where n is a positive integer from 4 to 6, whose method comprises: a) The attachment of a corresponding 3-carboxylic acid derivative thereof to the reaction of Hoffmann, Curtius or Schmidt; b) Acylation of a compound in which R is NH2 or NHR1 and the subjection of the acylamide optionally to reduction, or c) The reaction of a compound wherein R is NH2 or NHR1 with a suitable alkylene oxide, haloalkanecarboxylic acid or derivative thereof, alkyl halide, aminoalkyl halide, hydroxyalkyl halide or alkoxyalkyl halide, or d) The reaction of a compound wherein R is NHR1 or NR1R2 and wherein R1 and/or R2 contains an OH group with a halogenating agent and the subsequent substitution of the halogen with NH2, NHR3 or by NR3R4, or e) The reaction of a compound in which R is NH 2 with benzaldehyde, or f) The reaction of a compound in which R is NR5R6 with an oxidizing agent. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27713463A | 1963-05-01 | 1963-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES299134A1 true ES299134A1 (en) | 1964-09-01 |
Family
ID=23059539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0299134A Expired ES299134A1 (en) | 1963-05-01 | 1964-04-24 | Procedure for the preparation of an anti-virus provided composite (Machine-translation by Google Translate, not legally binding) |
Country Status (2)
| Country | Link |
|---|---|
| AT (3) | AT262957B (en) |
| ES (1) | ES299134A1 (en) |
-
1964
- 1964-04-22 AT AT354664A patent/AT262957B/en active
- 1964-04-22 AT AT199267A patent/AT269111B/en active
- 1964-04-22 AT AT804767A patent/AT273067B/en active
- 1964-04-24 ES ES0299134A patent/ES299134A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT269111B (en) | 1969-03-10 |
| AT262957B (en) | 1968-07-10 |
| AT273067B (en) | 1969-07-25 |
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