ES2986604T3 - Microvesículas terapéuticas de bacterias probióticas - Google Patents
Microvesículas terapéuticas de bacterias probióticas Download PDFInfo
- Publication number
- ES2986604T3 ES2986604T3 ES20722692T ES20722692T ES2986604T3 ES 2986604 T3 ES2986604 T3 ES 2986604T3 ES 20722692 T ES20722692 T ES 20722692T ES 20722692 T ES20722692 T ES 20722692T ES 2986604 T3 ES2986604 T3 ES 2986604T3
- Authority
- ES
- Spain
- Prior art keywords
- bacteria
- bacterial strain
- probiotic
- strain
- therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1950483 | 2019-04-17 | ||
| SE1951222 | 2019-10-25 | ||
| PCT/SE2020/050397 WO2020214083A1 (en) | 2019-04-17 | 2020-04-17 | Therapeutic microvesicles of probiotic bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2986604T3 true ES2986604T3 (es) | 2024-11-12 |
Family
ID=70476308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES20722692T Active ES2986604T3 (es) | 2019-04-17 | 2020-04-17 | Microvesículas terapéuticas de bacterias probióticas |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11857582B2 (pl) |
| EP (2) | EP3773648B1 (pl) |
| JP (1) | JP7556881B2 (pl) |
| KR (1) | KR102855825B1 (pl) |
| CN (1) | CN113747908B (pl) |
| AU (1) | AU2020258788B2 (pl) |
| BR (1) | BR112021019663A2 (pl) |
| CL (1) | CL2021002527A1 (pl) |
| EC (1) | ECSP21082738A (pl) |
| ES (1) | ES2986604T3 (pl) |
| HU (1) | HUE067741T2 (pl) |
| IL (1) | IL287226B2 (pl) |
| MX (1) | MX2021012631A (pl) |
| MY (1) | MY204586A (pl) |
| PH (1) | PH12021552578A1 (pl) |
| PL (1) | PL3773648T3 (pl) |
| SG (1) | SG11202110355RA (pl) |
| WO (1) | WO2020214083A1 (pl) |
| ZA (1) | ZA202106518B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113747908B (zh) | 2019-04-17 | 2025-07-18 | 生命大地女神有限公司 | 益生菌的治疗性微泡 |
| WO2022139530A1 (ko) * | 2020-12-23 | 2022-06-30 | 주식회사 리스큐어바이오사이언시스 | 락토바실러스 사케아이 유래 세포밖 소포체를 유효성분으로 포함하는 자가면역질환의 개선, 예방 또는 치료용 조성물 |
| CN113122478B (zh) * | 2021-04-26 | 2022-09-06 | 江南大学 | 一株能够缓解辣椒素致胃肠损伤的副干酪乳杆菌及其用途 |
| KR102850200B1 (ko) * | 2021-06-18 | 2025-08-27 | 경북대학교 산학협력단 | 핵산 백신 제조 및 유전자 전달을 위한 세균 유래 세포밖 소포체의 용도 |
| CN114292801A (zh) * | 2021-11-22 | 2022-04-08 | 龚志术 | 一种益生菌菌株的驯化方法、益生菌菌株、扶微乳及其制备方法 |
| WO2026017175A1 (zh) * | 2024-07-19 | 2026-01-22 | 内蒙古伊利实业集团股份有限公司 | 一种动物双歧杆菌的胞外囊泡及其提取方法和在治疗和/或预防神经损伤的应用 |
| KR102874901B1 (ko) * | 2025-05-12 | 2025-10-23 | 주식회사 코씨드바이오팜 | 수국 유래의 락티플란티바실러스 플란타룸 배양액에서 분리된 엑소좀을 함유하는 화장료 조성물 |
| CN120683017A (zh) * | 2025-07-04 | 2025-09-23 | 东莞市第八人民医院（东莞市儿童医院） | 一种乳酸杆菌来源的胞外囊泡及其在防治坏死性小肠结肠炎的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716938A1 (de) * | 1986-05-23 | 1987-11-26 | Heise Dieter | Arzneimittel zur behandlung von koliken im saeuglingsalter |
| US7374924B2 (en) | 2006-06-05 | 2008-05-20 | Biogaia Ab | Use of selected lactic acid bacteria for reducing infantile colic |
| US8617537B2 (en) | 2008-06-10 | 2013-12-31 | Biogaia Ab | Controlled activation of the reuterin-production machinery of lactobacillus |
| WO2011027971A2 (ko) * | 2009-09-01 | 2011-03-10 | 주식회사이언메딕스 | 장내 공생 세균유래 세포밖 소포체, 및 이를 이용한 질병모델, 백신, 후보 약물 탐색 방법, 및 진단 방법 |
| JP5635690B2 (ja) * | 2010-07-01 | 2014-12-03 | ポステック アカデミー‐インダストリー ファウンデーション | 細菌由来マイクロベシクルを用いた癌治療及び癌診断方法 |
| EP3693010A1 (en) * | 2012-04-06 | 2020-08-12 | Cornell University | Subunit vaccine delivery platform for robust humoral and cellular immune responses |
| WO2017018440A1 (ja) | 2015-07-27 | 2017-02-02 | セティ株式会社 | 乳酸菌組成物、発酵乳及びその製造方法、並びに発酵乳製造キット |
| KR102394638B1 (ko) | 2015-09-30 | 2022-05-09 | (주)아모레퍼시픽 | 유산균 유래의 세포외 소낭을 포함하는 탈모 방지 또는 육모 촉진용 조성물 |
| KR20180019474A (ko) * | 2016-08-16 | 2018-02-26 | 주식회사 엠디헬스케어 | 락토바실러스 플란타룸 유래 소포를 포함하는 정신질환 예방 또는 치료용 조성물 |
| EP3618843A1 (en) * | 2017-05-05 | 2020-03-11 | Société des Produits Nestlé S.A. | Treatment of infant colic |
| KR101853603B1 (ko) | 2017-05-18 | 2018-05-02 | 주식회사 쎌바이오텍 | 알코올 또는 아세트알데하이드 분해용 프로바이오틱스를 포함하는 조성물 |
| KR102348048B1 (ko) * | 2017-06-29 | 2022-01-10 | (주)아모레퍼시픽 | 유산균 유래의 세포밖 베지클을 포함하는 항노화용 조성물 |
| EP3678693A1 (en) * | 2017-09-08 | 2020-07-15 | Evelo Biosciences, Inc. | Bacterial extracellular vesicles |
| WO2019172598A1 (ko) * | 2018-03-05 | 2019-09-12 | 주식회사 엠디헬스케어 | 락토바실러스 속 세균 유래 나노소포 및 이의 용도 |
| US12059442B2 (en) | 2018-03-29 | 2024-08-13 | Morinaga Milk Industry Co., Ltd. | Obesity treatment using probiotics, composition for reducing body fat, and composition for reducing waist circumference |
| KR102233530B1 (ko) * | 2018-11-22 | 2021-03-31 | (주)프로스테믹스 | 엑소좀 및 이의 다양한 용도 |
| CN113747908B (zh) | 2019-04-17 | 2025-07-18 | 生命大地女神有限公司 | 益生菌的治疗性微泡 |
-
2020
- 2020-04-17 CN CN202080029182.9A patent/CN113747908B/zh active Active
- 2020-04-17 HU HUE20722692A patent/HUE067741T2/hu unknown
- 2020-04-17 EP EP20722692.9A patent/EP3773648B1/en active Active
- 2020-04-17 BR BR112021019663A patent/BR112021019663A2/pt unknown
- 2020-04-17 US US17/045,315 patent/US11857582B2/en active Active
- 2020-04-17 WO PCT/SE2020/050397 patent/WO2020214083A1/en not_active Ceased
- 2020-04-17 JP JP2021561738A patent/JP7556881B2/ja active Active
- 2020-04-17 MX MX2021012631A patent/MX2021012631A/es unknown
- 2020-04-17 SG SG11202110355RA patent/SG11202110355RA/en unknown
- 2020-04-17 EP EP24182877.1A patent/EP4410298A3/en not_active Withdrawn
- 2020-04-17 ES ES20722692T patent/ES2986604T3/es active Active
- 2020-04-17 MY MYPI2021005679A patent/MY204586A/en unknown
- 2020-04-17 PL PL20722692.9T patent/PL3773648T3/pl unknown
- 2020-04-17 AU AU2020258788A patent/AU2020258788B2/en active Active
- 2020-04-17 IL IL287226A patent/IL287226B2/en unknown
- 2020-04-17 KR KR1020217036548A patent/KR102855825B1/ko active Active
- 2020-04-17 PH PH1/2021/552578A patent/PH12021552578A1/en unknown
-
2021
- 2021-09-06 ZA ZA2021/06518A patent/ZA202106518B/en unknown
- 2021-09-29 CL CL2021002527A patent/CL2021002527A1/es unknown
- 2021-11-17 EC ECSENADI202182738A patent/ECSP21082738A/es unknown
-
2023
- 2023-11-16 US US18/510,979 patent/US20240082325A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP7556881B2 (ja) | 2024-09-26 |
| MX2021012631A (es) | 2021-11-12 |
| CA3136978A1 (en) | 2020-10-22 |
| EP3773648A1 (en) | 2021-02-17 |
| IL287226B2 (en) | 2025-09-01 |
| ECSP21082738A (es) | 2022-01-31 |
| WO2020214083A1 (en) | 2020-10-22 |
| AU2020258788A1 (en) | 2021-10-28 |
| CN113747908A (zh) | 2021-12-03 |
| CL2021002527A1 (es) | 2022-04-22 |
| KR20220007609A (ko) | 2022-01-18 |
| EP4410298A2 (en) | 2024-08-07 |
| IL287226B1 (en) | 2025-05-01 |
| EP4410298A3 (en) | 2024-11-13 |
| JP2022529456A (ja) | 2022-06-22 |
| IL287226A (en) | 2021-12-01 |
| BR112021019663A2 (pt) | 2021-12-07 |
| MY204586A (en) | 2024-09-05 |
| NZ780609A (en) | 2025-03-28 |
| EP3773648B1 (en) | 2024-06-19 |
| HUE067741T2 (hu) | 2024-11-28 |
| PH12021552578A1 (en) | 2022-04-04 |
| US11857582B2 (en) | 2024-01-02 |
| EP3773648C0 (en) | 2024-06-19 |
| SG11202110355RA (en) | 2021-11-29 |
| PL3773648T3 (pl) | 2024-08-26 |
| ZA202106518B (en) | 2025-01-29 |
| US20210154245A1 (en) | 2021-05-27 |
| CN113747908B (zh) | 2025-07-18 |
| KR102855825B1 (ko) | 2025-09-11 |
| AU2020258788B2 (en) | 2024-07-04 |
| US20240082325A1 (en) | 2024-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2986604T3 (es) | Microvesículas terapéuticas de bacterias probióticas | |
| Abdolalipour et al. | Evaluation of the antitumor immune responses of probiotic Bifidobacterium bifidum in human papillomavirus-induced tumor model | |
| Engevik et al. | Immunomodulation of dendritic cells by Lactobacillus reuteri surface components and metabolites | |
| WO2024184260A2 (en) | Composition comprising bifidobacterium longum subsp. infantis, bifidobacterium breve and 2'-fucosyllactose | |
| Shin et al. | Assessment of cell adhesion, cell surface hydrophobicity, autoaggregation, and lipopolysaccharide-binding properties of live and heat-killed Lactobacillus acidophilus CBT LA1 | |
| CN113164533B (zh) | 包含乳杆菌属的代谢健康用益生菌补充剂 | |
| EP4402245A1 (fr) | Souche bactérienne dans la prévention et/ou le traitement de pathologies inflammatoires | |
| Dabous et al. | A probiotic multi-strain mixture combined with hydroxyectoine improves intestinal barrier function by alleviating inflammation in lipopolysaccharide stimulated differentiated Caco-2 cells | |
| CA3136978C (en) | Therapeutic microvesicles of probiotic bacteria | |
| RU2836904C2 (ru) | Терапевтические микровезикулы, полученные из пробиотических бактерий | |
| Kang et al. | Evaluating the immunomodulation effects of live lactic acid bacteria from kimchi on Transwell Caco-2 monolayer permeability | |
| HK40062392B (zh) | 益生菌的治疗性微泡 | |
| HK40062392A (zh) | 益生菌的治疗性微泡 | |
| Garg et al. | Immunorestorative effects of Limosilactobacillus reuteri LR6 in protein-energy malnourished mice under pathogen and allergen challenge | |
| Gotova et al. | Selected Lactobacillus bulgaricus and Streptococcus thermophilus strains from bulgarian yogurt demonstrate significant anti-inflammatory potential | |
| JP7835954B2 (ja) | 乳酸菌及び免疫賦活剤 | |
| Stamatova et al. | Probiotic challenge of oral epithelial cells in vitro | |
| Karimi | Exploring probiotics-host interactions | |
| CN115161215A (zh) | 一种双歧杆菌的发酵方法及其应用 | |
| Rossi et al. | Differential cytokine induction and TLR signalling by Faecalibacterium prausnitzii and other commensal intestinal bacteria | |
| HK40047699A (en) | Probiotic supplement for metabolic health comprising lactobacillus | |
| TO | MODULATORS OF INNATE GUT IMMUNITY TO ENTERIC VIRAL INFECTIONS: MURINE NOROVIRUS (MNV) AS A MODEL | |
| Ngeny | Effects of Lactobacillus rhamnosus Milk Isolate on the Production of Inflammatory Cytokines in Enterocytes |