CL2021002527A1 - Microvesiculas terapeuticas de bacterias probióticas. - Google Patents

Microvesiculas terapeuticas de bacterias probióticas.

Info

Publication number
CL2021002527A1
CL2021002527A1 CL2021002527A CL2021002527A CL2021002527A1 CL 2021002527 A1 CL2021002527 A1 CL 2021002527A1 CL 2021002527 A CL2021002527 A CL 2021002527A CL 2021002527 A CL2021002527 A CL 2021002527A CL 2021002527 A1 CL2021002527 A1 CL 2021002527A1
Authority
CL
Chile
Prior art keywords
therapeutic microvesicles
probiotic bacteria
bacteria
microvesicles
therapeutic
Prior art date
Application number
CL2021002527A
Other languages
English (en)
Inventor
Stefan Roos
Wolfgan Kunze
John Bienenstock
Original Assignee
Biogaia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogaia Ab filed Critical Biogaia Ab
Publication of CL2021002527A1 publication Critical patent/CL2021002527A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Un método para proporcionar microvesículas terapéuticas a partir de bacterias probióticas que comprende exponer las bacterias a un tratamiento inductor durante el cultivo para inducir la producción de microvesículas terapéuticas por las bacterias. Las microvesículas terapéuticas se pueden usar en el tratamiento de, por ejemplo, cólicos, un trastorno o enfermedad gastrointestinal infantil, un trastorno de dolor gastrointestinal, una enfermedad de pérdida ósea y / o una enfermedad periodontal.
CL2021002527A 2019-04-17 2021-09-29 Microvesiculas terapeuticas de bacterias probióticas. CL2021002527A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1950483 2019-04-17
SE1951222 2019-10-25

Publications (1)

Publication Number Publication Date
CL2021002527A1 true CL2021002527A1 (es) 2022-04-22

Family

ID=70476308

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2021002527A CL2021002527A1 (es) 2019-04-17 2021-09-29 Microvesiculas terapeuticas de bacterias probióticas.

Country Status (15)

Country Link
US (2) US11857582B2 (es)
EP (2) EP4410298A2 (es)
JP (1) JP7556881B2 (es)
KR (1) KR20220007609A (es)
CN (1) CN113747908A (es)
AU (1) AU2020258788B2 (es)
BR (1) BR112021019663A2 (es)
CA (1) CA3136978A1 (es)
CL (1) CL2021002527A1 (es)
EC (1) ECSP21082738A (es)
IL (1) IL287226A (es)
MX (1) MX2021012631A (es)
PL (1) PL3773648T3 (es)
SG (1) SG11202110355RA (es)
WO (1) WO2020214083A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7556881B2 (ja) 2019-04-17 2024-09-26 バイオガイア エイビー プロバイオティック細菌の治療用マイクロベシクル
WO2022139530A1 (ko) * 2020-12-23 2022-06-30 주식회사 리스큐어바이오사이언시스 락토바실러스 사케아이 유래 세포밖 소포체를 유효성분으로 포함하는 자가면역질환의 개선, 예방 또는 치료용 조성물
CN113122478B (zh) * 2021-04-26 2022-09-06 江南大学 一株能够缓解辣椒素致胃肠损伤的副干酪乳杆菌及其用途
CN114292801A (zh) * 2021-11-22 2022-04-08 龚志术 一种益生菌菌株的驯化方法、益生菌菌株、扶微乳及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716938A1 (de) * 1986-05-23 1987-11-26 Heise Dieter Arzneimittel zur behandlung von koliken im saeuglingsalter
US7374924B2 (en) 2006-06-05 2008-05-20 Biogaia Ab Use of selected lactic acid bacteria for reducing infantile colic
US8617537B2 (en) 2008-06-10 2013-12-31 Biogaia Ab Controlled activation of the reuterin-production machinery of lactobacillus
CN103079592B (zh) * 2010-07-01 2015-10-21 浦项工科大学校产学协力团 使用来自细胞的微泡治疗和诊断癌症的方法
JP6858406B2 (ja) 2015-07-27 2021-04-14 セティ株式会社 乳酸菌組成物、発酵乳及びその製造方法、並びに発酵乳製造キット
KR102394638B1 (ko) 2015-09-30 2022-05-09 (주)아모레퍼시픽 유산균 유래의 세포외 소낭을 포함하는 탈모 방지 또는 육모 촉진용 조성물
MX2019013143A (es) * 2017-05-05 2020-07-14 Nestle Sa Tratamiento de colicos infantiles.
KR101853603B1 (ko) 2017-05-18 2018-05-02 주식회사 쎌바이오텍 알코올 또는 아세트알데하이드 분해용 프로바이오틱스를 포함하는 조성물
US12059442B2 (en) 2018-03-29 2024-08-13 Morinaga Milk Industry Co., Ltd. Obesity treatment using probiotics, composition for reducing body fat, and composition for reducing waist circumference
JP7556881B2 (ja) 2019-04-17 2024-09-26 バイオガイア エイビー プロバイオティック細菌の治療用マイクロベシクル

Also Published As

Publication number Publication date
IL287226A (en) 2021-12-01
BR112021019663A2 (pt) 2021-12-07
AU2020258788B2 (en) 2024-07-04
US20210154245A1 (en) 2021-05-27
CN113747908A (zh) 2021-12-03
CA3136978A1 (en) 2020-10-22
PL3773648T3 (pl) 2024-08-26
WO2020214083A1 (en) 2020-10-22
EP3773648A1 (en) 2021-02-17
MX2021012631A (es) 2021-11-12
ECSP21082738A (es) 2022-01-31
EP4410298A2 (en) 2024-08-07
EP3773648C0 (en) 2024-06-19
AU2020258788A1 (en) 2021-10-28
US20240082325A1 (en) 2024-03-14
JP7556881B2 (ja) 2024-09-26
KR20220007609A (ko) 2022-01-18
EP3773648B1 (en) 2024-06-19
US11857582B2 (en) 2024-01-02
SG11202110355RA (en) 2021-11-29
JP2022529456A (ja) 2022-06-22

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