BR112021019663A2 - Método para produzir microvesículas terapêuticas, composição probiótica, microvesículas terapêuticas, e, cepa bacteriana - Google Patents
Método para produzir microvesículas terapêuticas, composição probiótica, microvesículas terapêuticas, e, cepa bacterianaInfo
- Publication number
- BR112021019663A2 BR112021019663A2 BR112021019663A BR112021019663A BR112021019663A2 BR 112021019663 A2 BR112021019663 A2 BR 112021019663A2 BR 112021019663 A BR112021019663 A BR 112021019663A BR 112021019663 A BR112021019663 A BR 112021019663A BR 112021019663 A2 BR112021019663 A2 BR 112021019663A2
- Authority
- BR
- Brazil
- Prior art keywords
- therapeutic microvesicles
- microvesicles
- therapeutic
- bacterial strain
- probiotic composition
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000006041 probiotic Substances 0.000 title abstract 3
- 230000000529 probiotic effect Effects 0.000 title abstract 3
- 235000018291 probiotics Nutrition 0.000 title abstract 3
- 230000001580 bacterial effect Effects 0.000 title abstract 2
- 241000894006 Bacteria Species 0.000 abstract 3
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 2
- 208000010643 digestive system disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000018685 gastrointestinal system disease Diseases 0.000 abstract 2
- 208000004998 Abdominal Pain Diseases 0.000 abstract 1
- 206010065687 Bone loss Diseases 0.000 abstract 1
- 208000002881 Colic Diseases 0.000 abstract 1
- 206010017999 Gastrointestinal pain Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 238000011419 induction treatment Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
método para produzir microvesículas terapêuticas, composição probiótica, microvesículas terapêuticas, e, cepa bacteriana campo técnico. um método para prover microvesículas terapêuticas a partir de bactérias probióticas compreende expor as bactérias a um tratamento de indução durante o cultivo para induzir produção de microvesículas terapêuticas pelas bactérias. as microvesículas terapêuticas podem ser usadas no tratamento de, por exemplo, cólica, um distúrbio ou doença gastrointestinal infantil ou da infância, um distúrbio de dor gastrointestinal, uma doença de perda óssea e/ou uma doença periodontal.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1950483 | 2019-04-17 | ||
| SE1951222 | 2019-10-25 | ||
| PCT/SE2020/050397 WO2020214083A1 (en) | 2019-04-17 | 2020-04-17 | Therapeutic microvesicles of probiotic bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021019663A2 true BR112021019663A2 (pt) | 2021-12-07 |
Family
ID=70476308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021019663A BR112021019663A2 (pt) | 2019-04-17 | 2020-04-17 | Método para produzir microvesículas terapêuticas, composição probiótica, microvesículas terapêuticas, e, cepa bacteriana |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11857582B2 (pt) |
| EP (1) | EP3773648B1 (pt) |
| JP (1) | JP2022529456A (pt) |
| KR (1) | KR20220007609A (pt) |
| CN (1) | CN113747908A (pt) |
| AU (1) | AU2020258788B2 (pt) |
| BR (1) | BR112021019663A2 (pt) |
| CA (1) | CA3136978A1 (pt) |
| CL (1) | CL2021002527A1 (pt) |
| EC (1) | ECSP21082738A (pt) |
| IL (1) | IL287226A (pt) |
| MX (1) | MX2021012631A (pt) |
| SG (1) | SG11202110355RA (pt) |
| WO (1) | WO2020214083A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3136978A1 (en) | 2019-04-17 | 2020-10-22 | Biogaia Ab | Therapeutic microvesicles of probiotic bacteria |
| WO2022139530A1 (ko) * | 2020-12-23 | 2022-06-30 | 주식회사 리스큐어바이오사이언시스 | 락토바실러스 사케아이 유래 세포밖 소포체를 유효성분으로 포함하는 자가면역질환의 개선, 예방 또는 치료용 조성물 |
| CN113122478B (zh) * | 2021-04-26 | 2022-09-06 | 江南大学 | 一株能够缓解辣椒素致胃肠损伤的副干酪乳杆菌及其用途 |
| CN114292801A (zh) * | 2021-11-22 | 2022-04-08 | 龚志术 | 一种益生菌菌株的驯化方法、益生菌菌株、扶微乳及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716938A1 (de) * | 1986-05-23 | 1987-11-26 | Heise Dieter | Arzneimittel zur behandlung von koliken im saeuglingsalter |
| EP2589391B1 (en) * | 2010-07-01 | 2018-11-14 | Rosetta Exosome Co., Ltd. | Bacterial cell-derived microvesicles for use in a method of treating cancer |
| MX2019013143A (es) * | 2017-05-05 | 2020-07-14 | Nestle Sa | Tratamiento de colicos infantiles. |
| CA3136978A1 (en) | 2019-04-17 | 2020-10-22 | Biogaia Ab | Therapeutic microvesicles of probiotic bacteria |
-
2020
- 2020-04-17 CA CA3136978A patent/CA3136978A1/en active Pending
- 2020-04-17 MX MX2021012631A patent/MX2021012631A/es unknown
- 2020-04-17 BR BR112021019663A patent/BR112021019663A2/pt unknown
- 2020-04-17 SG SG11202110355RA patent/SG11202110355RA/en unknown
- 2020-04-17 KR KR1020217036548A patent/KR20220007609A/ko unknown
- 2020-04-17 WO PCT/SE2020/050397 patent/WO2020214083A1/en unknown
- 2020-04-17 AU AU2020258788A patent/AU2020258788B2/en active Active
- 2020-04-17 JP JP2021561738A patent/JP2022529456A/ja active Pending
- 2020-04-17 US US17/045,315 patent/US11857582B2/en active Active
- 2020-04-17 CN CN202080029182.9A patent/CN113747908A/zh active Pending
- 2020-04-17 EP EP20722692.9A patent/EP3773648B1/en active Active
-
2021
- 2021-09-29 CL CL2021002527A patent/CL2021002527A1/es unknown
- 2021-10-13 IL IL287226A patent/IL287226A/en unknown
- 2021-11-17 EC ECSENADI202182738A patent/ECSP21082738A/es unknown
-
2023
- 2023-11-16 US US18/510,979 patent/US20240082325A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP21082738A (es) | 2022-01-31 |
| US20240082325A1 (en) | 2024-03-14 |
| AU2020258788A1 (en) | 2021-10-28 |
| MX2021012631A (es) | 2021-11-12 |
| JP2022529456A (ja) | 2022-06-22 |
| EP3773648B1 (en) | 2024-06-19 |
| SG11202110355RA (en) | 2021-11-29 |
| CL2021002527A1 (es) | 2022-04-22 |
| KR20220007609A (ko) | 2022-01-18 |
| US11857582B2 (en) | 2024-01-02 |
| CN113747908A (zh) | 2021-12-03 |
| AU2020258788B2 (en) | 2024-07-04 |
| IL287226A (en) | 2021-12-01 |
| US20210154245A1 (en) | 2021-05-27 |
| CA3136978A1 (en) | 2020-10-22 |
| EP3773648A1 (en) | 2021-02-17 |
| WO2020214083A1 (en) | 2020-10-22 |
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