ES2962509T3 - Métodos y composiciones para modificar ADN genómico - Google Patents
Métodos y composiciones para modificar ADN genómico Download PDFInfo
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- ES2962509T3 ES2962509T3 ES15780038T ES15780038T ES2962509T3 ES 2962509 T3 ES2962509 T3 ES 2962509T3 ES 15780038 T ES15780038 T ES 15780038T ES 15780038 T ES15780038 T ES 15780038T ES 2962509 T3 ES2962509 T3 ES 2962509T3
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- C12N5/0634—Cells from the blood or the immune system
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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ES15780038T Active ES2962509T3 (es) | 2014-04-14 | 2015-04-13 | Métodos y composiciones para modificar ADN genómico |
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WO (1) | WO2015160683A1 (pt) |
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US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
WO2015066119A1 (en) | 2013-10-30 | 2015-05-07 | North Carolina State University | Compositions and methods related to a type-ii crispr-cas system in lactobacillus buchneri |
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US9068179B1 (en) | 2013-12-12 | 2015-06-30 | President And Fellows Of Harvard College | Methods for correcting presenilin point mutations |
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