ES2959198T3 - Compuestos análogos de pirfenidona y piridona en aerosol - Google Patents

Compuestos análogos de pirfenidona y piridona en aerosol Download PDF

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Publication number
ES2959198T3
ES2959198T3 ES13822166T ES13822166T ES2959198T3 ES 2959198 T3 ES2959198 T3 ES 2959198T3 ES 13822166 T ES13822166 T ES 13822166T ES 13822166 T ES13822166 T ES 13822166T ES 2959198 T3 ES2959198 T3 ES 2959198T3
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ES
Spain
Prior art keywords
pirfenidone
dose
administration
approximately
lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13822166T
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English (en)
Spanish (es)
Inventor
Mark Surber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avalyn Pharma Inc
Original Assignee
Avalyn Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalyn Pharma Inc filed Critical Avalyn Pharma Inc
Application granted granted Critical
Publication of ES2959198T3 publication Critical patent/ES2959198T3/es
Active legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES13822166T 2012-07-24 2013-07-24 Compuestos análogos de pirfenidona y piridona en aerosol Active ES2959198T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261675286P 2012-07-24 2012-07-24
US201361756983P 2013-01-25 2013-01-25
US201361824818P 2013-05-17 2013-05-17
PCT/US2013/051880 WO2014018668A2 (en) 2012-07-24 2013-07-24 Aerosol pirfenidone and pyridone analog compounds and uses thereof

Publications (1)

Publication Number Publication Date
ES2959198T3 true ES2959198T3 (es) 2024-02-21

Family

ID=49997965

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13822166T Active ES2959198T3 (es) 2012-07-24 2013-07-24 Compuestos análogos de pirfenidona y piridona en aerosol

Country Status (8)

Country Link
EP (1) EP2877164B1 (https=)
JP (5) JP6501264B2 (https=)
AU (5) AU2013295800A1 (https=)
CA (1) CA2880011C (https=)
ES (1) ES2959198T3 (https=)
HU (1) HUE063581T2 (https=)
NZ (1) NZ705260A (https=)
WO (1) WO2014018668A2 (https=)

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JP6021117B2 (ja) 2011-01-31 2016-11-02 ジェノア ファーマシューティカルズ,インク. エアロゾルのピルフェニドンおよびピリドンアナログの化合物、および、その使用
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
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JP6799201B2 (ja) 2013-07-31 2020-12-16 アヴァリン ファーマ インク. エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用
NZ760541A (en) 2014-01-10 2022-08-26 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX382781B (es) 2014-04-02 2025-03-13 Intermune Inc Piridinonas anti-fibroticas.
RU2726367C2 (ru) * 2016-03-28 2020-07-13 Пресидж Байосайенсиз, Инк. Фармацевтические комбинации для лечения злокачественной опухоли
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WO2018234527A1 (en) * 2017-06-22 2018-12-27 Softhale Nv Aerosol delivery of pirfenidone
ES3032673T3 (en) * 2017-06-22 2025-07-23 Invox Belgium Nv Aerosol delivery of pirfenidone
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EP4424379A3 (en) 2019-04-24 2024-10-30 Convergene Llc Small molecule bromodomain inhibitors and uses thereof
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JP7490813B2 (ja) * 2020-04-22 2024-05-27 ユンジン ファーム.カンパニー、リミテッド 安全性と安定性が改善されたピルフェニドンを含む腸溶性製剤およびその製造方法
AU2021396535A1 (en) * 2020-12-07 2023-06-22 Mannkind Corporation Method and composition for treating pulmonary fibrosis
US12508228B2 (en) 2022-03-30 2025-12-30 The Chinese University Of Hong Kong PFD loaded microspheres and method for preparing injectable composite microsphere hydrogel solution from same
CN115970069B (zh) * 2022-12-13 2024-09-24 南通大学附属医院 载吡非尼酮纳米粒子复合涂层输尿管支架管的制备方法
CN119548479A (zh) * 2024-12-31 2025-03-04 延边大学 一种吸入用吡非尼酮溶液及其使用方法

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Also Published As

Publication number Publication date
NZ705260A (en) 2017-04-28
JP2015523395A (ja) 2015-08-13
JP2018172402A (ja) 2018-11-08
JP2020073494A (ja) 2020-05-14
AU2013295800A1 (en) 2015-03-19
EP2877164A2 (en) 2015-06-03
EP2877164B1 (en) 2023-07-05
AU2020201557A1 (en) 2020-03-26
AU2022271417A1 (en) 2022-12-22
AU2020201557B2 (en) 2022-08-25
JP6501264B2 (ja) 2019-04-17
CA2880011C (en) 2021-02-16
AU2024267029A1 (en) 2024-12-19
WO2014018668A2 (en) 2014-01-30
JP2022078126A (ja) 2022-05-24
EP2877164C0 (en) 2023-07-05
JP7120984B2 (ja) 2022-08-17
HK1210955A1 (en) 2016-05-13
HUE063581T2 (hu) 2024-01-28
WO2014018668A3 (en) 2014-10-16
CA2880011A1 (en) 2014-01-30
JP2024095678A (ja) 2024-07-10
AU2018206852A1 (en) 2018-08-09
EP2877164A4 (en) 2016-01-13

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