ES2955711T3 - Regímenes de dosificación para el tratamiento de infecciones fúngicas - Google Patents

Regímenes de dosificación para el tratamiento de infecciones fúngicas Download PDF

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Publication number
ES2955711T3
ES2955711T3 ES17767455T ES17767455T ES2955711T3 ES 2955711 T3 ES2955711 T3 ES 2955711T3 ES 17767455 T ES17767455 T ES 17767455T ES 17767455 T ES17767455 T ES 17767455T ES 2955711 T3 ES2955711 T3 ES 2955711T3
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ES
Spain
Prior art keywords
dose
saline
neutral form
administered
day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17767455T
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English (en)
Spanish (es)
Inventor
Kenneth Bartizal
Paul Daruwala
Jeffrey Locke
Voon Ong
Taylor Sandison
Dirk Thye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cidara Therapeutics Inc
Original Assignee
Cidara Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cidara Therapeutics Inc filed Critical Cidara Therapeutics Inc
Application granted granted Critical
Publication of ES2955711T3 publication Critical patent/ES2955711T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961Plant cells or fungi

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES17767455T 2016-03-16 2017-03-15 Regímenes de dosificación para el tratamiento de infecciones fúngicas Active ES2955711T3 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662309211P 2016-03-16 2016-03-16
US201662350591P 2016-06-15 2016-06-15
US201662415928P 2016-11-01 2016-11-01
US201662418727P 2016-11-07 2016-11-07
US201662419076P 2016-11-08 2016-11-08
US201662436716P 2016-12-20 2016-12-20
PCT/US2017/022551 WO2017161016A1 (en) 2016-03-16 2017-03-15 Dosing regimens for treatment of fungal infections

Publications (1)

Publication Number Publication Date
ES2955711T3 true ES2955711T3 (es) 2023-12-05

Family

ID=59850952

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17767455T Active ES2955711T3 (es) 2016-03-16 2017-03-15 Regímenes de dosificación para el tratamiento de infecciones fúngicas

Country Status (8)

Country Link
US (2) US11712459B2 (enExample)
EP (2) EP3430400B1 (enExample)
JP (3) JP7224916B2 (enExample)
CN (1) CN109154603A (enExample)
CA (1) CA3017485A1 (enExample)
ES (1) ES2955711T3 (enExample)
MA (1) MA43825A (enExample)
WO (1) WO2017161016A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE036778T2 (hu) 2011-03-03 2018-07-30 Cidara Therapeutics Inc Gombaellenes szerek és alkalmazásuk
EP2827710B1 (en) 2012-03-19 2019-11-20 Cidara Therapeutics, Inc. Dosing regimens for echinocandin class compounds
WO2017120471A1 (en) 2016-01-08 2017-07-13 Cidara Therapeutics, Inc. Methods for preventing and treating pneumocystis infections
US11712459B2 (en) 2016-03-16 2023-08-01 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
CA3069423C (en) 2017-07-12 2025-04-15 Cidara Therapeutics Inc Formulations for the treatment of fungal infections
WO2019241626A1 (en) 2018-06-15 2019-12-19 Cidara Therapeutics, Inc. Synthesis of echinocandin antifungal agent
US12060439B2 (en) 2018-10-25 2024-08-13 Napp Pharmaceutical Group Limited Polymorph of echinocandin antifungal agent
WO2020232037A1 (en) * 2019-05-16 2020-11-19 Scynexis, Inc. Antifungal agents, like ibrexafungerp for candida auris decolonization

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427660A (en) 1982-03-03 1984-01-24 Research Corporation Formyl-methionyl chemotatic peptide antibiotic conjugates useful in treating infections
US5166135A (en) 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
US6030944A (en) 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
US5399552A (en) 1991-10-17 1995-03-21 Merck & Co, Inc Antibiotic peptides bearing aminoalkylthioether moieties
US5378804A (en) 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US6268338B1 (en) 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
EP0697879A4 (en) 1993-05-04 1998-01-14 Merck & Co Inc AMINOALKYL ETHER DERIVATIVES OF CYCLOHEXAPEPTIDES
US5948753A (en) 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
US5541160A (en) 1994-04-04 1996-07-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5514651A (en) 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516756A (en) 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
CA2211138A1 (en) 1995-01-26 1996-08-01 Merck & Co., Inc. Novel antifungal cyclohexapeptides
US5652213A (en) 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
AR006598A1 (es) 1996-04-19 1999-09-08 Merck Sharp & Dohme "composiciones anti-fungosas, su uso en la manufactura de medicamentos y un procedimiento para su preparación"
USRE38984E1 (en) 1996-09-12 2006-02-14 Merck & Co., Inc. Antifungal combination therapy
AU766091B2 (en) 1998-12-09 2003-10-09 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
DK1582204T3 (da) 1999-03-03 2013-11-04 Lilly Co Eli Echinocandin-farmaceutiske formuleringer, der indeholder miceldannende overfladeaktive stoffer
IL145188A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Processes for making pharmaceutical oral ecb formulations and compositions
US6309622B1 (en) * 1999-03-26 2001-10-30 Protech Professional Products, Inc. Antimicrobial denture cleansing compositions
EP1172105A4 (en) * 1999-04-16 2002-09-04 Fujisawa Pharmaceutical Co ANTIFUNGAL COMPOSITIONS
HU0104790D0 (en) 2001-11-08 2002-01-28 Human Rt Pharmaceutical combinations for topical application
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
EP1576150A4 (en) 2002-10-16 2006-05-03 Univ Texas METHOD AND COMPOSITIONS TO SAVE THE EFFECTIVENESS OF BIOLOGICALLY ACTIVE INGREDIENTS
US6913759B2 (en) 2003-03-11 2005-07-05 Curatek Pharmaceuticals Holding, Inc. Gel composition and method for treatment of vaginal infections
EP1654036B1 (en) 2003-07-22 2007-12-26 Theravance, Inc. Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
EP1907588B1 (en) 2005-07-26 2013-06-05 The University of Medicine and Dentistry of New Jersey Assays for resistance to echinocandin-class drugs
US20070231258A1 (en) 2006-03-31 2007-10-04 Karyon Ctt Ltd. Peptide conjugates
GB0702020D0 (en) 2007-02-02 2007-03-14 Novabiotics Ltd Peptides and their use
US20090238867A1 (en) 2007-12-13 2009-09-24 Scott Jenkins Nanoparticulate Anidulafungin Compositions and Methods for Making the Same
US20100009009A1 (en) 2008-07-10 2010-01-14 Micropure, Inc. Method and composition for prevention and treatment of oral fungal infections
GB0817121D0 (en) 2008-09-18 2008-10-29 Univ St Andrews Anti-fungal therapy
US10568859B2 (en) 2009-02-25 2020-02-25 Mayne Pharma Llc Topical foam composition
WO2010128096A1 (en) 2009-05-07 2010-11-11 Dsm Ip Assets B.V. Method for the preparation of cyclopeptides
EP2470168B1 (en) 2009-08-26 2018-01-31 BioElectron Technology Corporation Methods for the prevention and treatment of cerebral ischemia
EP2470190A4 (en) 2009-08-27 2013-07-17 Seachaid Pharmaceuticals Inc ECHINOCANDINDERIVATE
EP2525831B1 (en) 2010-01-22 2019-05-15 Ascendis Pharma A/S Carrier-linked carbamate prodrug linkers
HUE036778T2 (hu) 2011-03-03 2018-07-30 Cidara Therapeutics Inc Gombaellenes szerek és alkalmazásuk
EP2739652B1 (en) 2011-08-04 2017-04-05 Medizinische Universität Innsbruck Cahgt1p inhibitors for use in the treatment of candidiasis
US8829053B2 (en) 2011-12-07 2014-09-09 Rochal Industries Llp Biocidal compositions and methods of using the same
EP2827710B1 (en) 2012-03-19 2019-11-20 Cidara Therapeutics, Inc. Dosing regimens for echinocandin class compounds
CN102766198A (zh) 2012-05-04 2012-11-07 中国人民解放军第二军医大学 一种糖肽类抗真菌化合物及其制备方法与应用
WO2014113693A1 (en) 2013-01-18 2014-07-24 University Of Utah Research Foundation Modified release osmotic pump for ph-responsive intravaginal drug delivery
WO2014124504A1 (en) 2013-02-13 2014-08-21 Katholieke Universiteit Leuven Ku Leuven Research & Development Compositions and methods for treating biofilms
US9919055B2 (en) 2013-03-15 2018-03-20 Arizona Board Of Regents On Behalf Of Arizona State University Sugar-linker-drug conjugates
CN112656782A (zh) 2013-05-01 2021-04-16 尼奥酷里私人有限公司 治疗细菌感染的方法
US20160213742A1 (en) 2013-09-04 2016-07-28 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
US20180256673A1 (en) 2015-09-16 2018-09-13 Cidara Therapeutics, Inc. Methods for treating fungal infections
WO2017049105A1 (en) 2015-09-16 2017-03-23 Cidara Therapeutics, Inc. Formulations for treating fungal infections
WO2017120471A1 (en) 2016-01-08 2017-07-13 Cidara Therapeutics, Inc. Methods for preventing and treating pneumocystis infections
US11712459B2 (en) 2016-03-16 2023-08-01 Cidara Therapeutics, Inc. Dosing regimens for treatment of fungal infections
CN110290797A (zh) 2016-11-01 2019-09-27 奇达拉治疗公司 用于预防和治疗真菌感染的单剂量方法
US20210002346A1 (en) 2016-11-29 2021-01-07 Cidara Therapeutics, Inc Methods for preventing fungal infections
WO2018144600A1 (en) 2017-01-31 2018-08-09 Cidara Therapeutics, Inc. Methods for treating fungal infections
WO2018187574A1 (en) 2017-04-05 2018-10-11 Cidara Therapeutics, Inc. Compositions and methods for the treatment of fungal infections
WO2018191692A1 (en) 2017-04-14 2018-10-18 Cidara Therapeutics, Inc. Methods for treating fungal infections
CA3069423C (en) 2017-07-12 2025-04-15 Cidara Therapeutics Inc Formulations for the treatment of fungal infections
US20200164023A1 (en) 2017-08-03 2020-05-28 Cidara Therapeutics, Inc. Methods for preventing and treating intra-abdominal candidiasis
WO2019241626A1 (en) 2018-06-15 2019-12-19 Cidara Therapeutics, Inc. Synthesis of echinocandin antifungal agent

Also Published As

Publication number Publication date
JP7224916B2 (ja) 2023-02-20
JP7322259B2 (ja) 2023-08-07
WO2017161016A1 (en) 2017-09-21
MA43825A (fr) 2021-04-07
JP2019511496A (ja) 2019-04-25
CN109154603A (zh) 2019-01-04
CA3017485A1 (en) 2017-09-21
EP4268896A3 (en) 2024-01-03
EP3430400A1 (en) 2019-01-23
EP3430400A4 (en) 2019-10-30
JP2022169599A (ja) 2022-11-09
US11712459B2 (en) 2023-08-01
EP4268896A2 (en) 2023-11-01
EP3430400B1 (en) 2023-06-21
US20240108684A1 (en) 2024-04-04
US20190216885A1 (en) 2019-07-18
JP2023139211A (ja) 2023-10-03

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