ES2947634T3 - Biomarcadores microARN séricos circulantes y métodos para determinar la enfermedad de Parkinson - Google Patents
Biomarcadores microARN séricos circulantes y métodos para determinar la enfermedad de Parkinson Download PDFInfo
- Publication number
- ES2947634T3 ES2947634T3 ES17706344T ES17706344T ES2947634T3 ES 2947634 T3 ES2947634 T3 ES 2947634T3 ES 17706344 T ES17706344 T ES 17706344T ES 17706344 T ES17706344 T ES 17706344T ES 2947634 T3 ES2947634 T3 ES 2947634T3
- Authority
- ES
- Spain
- Prior art keywords
- mir
- hsa
- seq
- mirnas
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662291619P | 2016-02-05 | 2016-02-05 | |
| PCT/US2017/016412 WO2017136662A1 (en) | 2016-02-05 | 2017-02-03 | Circulating serum microrna biomarkers and methods for determining parkinson's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2947634T3 true ES2947634T3 (es) | 2023-08-14 |
Family
ID=58094505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17706344T Active ES2947634T3 (es) | 2016-02-05 | 2017-02-03 | Biomarcadores microARN séricos circulantes y métodos para determinar la enfermedad de Parkinson |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11499184B2 (enExample) |
| EP (2) | EP3985130A1 (enExample) |
| JP (1) | JP7197755B2 (enExample) |
| ES (1) | ES2947634T3 (enExample) |
| WO (1) | WO2017136662A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020524509A (ja) * | 2017-06-19 | 2020-08-20 | セント・ジョーンズ・ユニバーシティＳｔ． Ｊｏｈｎｓ Ｕｎｉｖｅｒｓｉｔｙ | アルツハイマー病の診断のための循環血清マイクロｒｎａバイオマーカー及び方法 |
| EP3850108A4 (en) * | 2018-10-18 | 2022-08-03 | Quadrant Biosciences Inc. | MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF EARLY-STAGE PARKINSON'S DISEASE AND TREATMENTS |
| EP3937986A4 (en) * | 2019-03-11 | 2023-04-12 | Ochsner Health System | MICRORNA REGULATORY NETWORK AS A BIOMARKER OF SEIZURES IN PATIENTS WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE |
| WO2020213699A1 (ja) * | 2019-04-17 | 2020-10-22 | 京都府公立大学法人 | 自己免疫疾患及び／又は炎症性疾患の判定方法、並びに炎症性疾患及び／又は自己免疫疾患の予防及び／又は治療剤 |
| CN111073973A (zh) * | 2019-12-10 | 2020-04-28 | 石河子大学 | 一种用于早期诊断2型糖尿病的microRNA序列及其应用 |
| WO2021230379A1 (ja) | 2020-05-14 | 2021-11-18 | 花王株式会社 | パーキンソン病の検出方法 |
| WO2022165024A1 (en) * | 2021-01-27 | 2022-08-04 | Beth Israel Deaconess Medical Center | Electrophoretic mobility shift as a molecular beacon-based readout for mirna detection |
| WO2023050642A1 (zh) * | 2021-09-29 | 2023-04-06 | 南京凡亦达生物科技有限公司 | 甲胎蛋白或癌胚抗原联合基因标志物在肿瘤诊断中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013036936A1 (en) * | 2011-09-09 | 2013-03-14 | Van Andel Research Institute | Microrna biomarkers for diagnosing parkinson's disease |
| US9540692B2 (en) * | 2012-07-25 | 2017-01-10 | Rush University Medical Center | MiRNAs as novel therapeutic targets and diagnostic biomarkers for parkinsons disease |
| US10011873B2 (en) | 2012-11-16 | 2018-07-03 | Universitat Des Saarlandes | Diagnostic miRNA markers for Parkinson disease |
| US11293064B2 (en) * | 2013-05-02 | 2022-04-05 | Thomas Jefferson University | Human miRNAs for use in diagnosis, prognosis, and therapy of human conditions and diseases |
| US10961579B2 (en) | 2013-12-19 | 2021-03-30 | Hummingbird Diagnostics Gmbh | miRNAs as non-invasive biomarkers for Parkinson's disease |
| WO2015106273A2 (en) * | 2014-01-13 | 2015-07-16 | Trustees Of Boston University | Methods and assays relating to huntingtons disease and parkinson's disease |
-
2017
- 2017-02-03 ES ES17706344T patent/ES2947634T3/es active Active
- 2017-02-03 JP JP2018560445A patent/JP7197755B2/ja active Active
- 2017-02-03 EP EP21198200.4A patent/EP3985130A1/en active Pending
- 2017-02-03 US US16/075,354 patent/US11499184B2/en active Active
- 2017-02-03 EP EP17706344.3A patent/EP3411500B9/en active Active
- 2017-02-03 WO PCT/US2017/016412 patent/WO2017136662A1/en not_active Ceased
-
2022
- 2022-10-07 US US18/045,065 patent/US20230323442A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017136662A1 (en) | 2017-08-10 |
| EP3985130A1 (en) | 2022-04-20 |
| WO2017136662A4 (en) | 2017-08-31 |
| JP7197755B2 (ja) | 2022-12-28 |
| EP3411500B1 (en) | 2023-06-07 |
| US20200354768A1 (en) | 2020-11-12 |
| EP3411500C0 (en) | 2023-06-07 |
| EP3411500B9 (en) | 2023-10-04 |
| US20230323442A1 (en) | 2023-10-12 |
| EP3411500A1 (en) | 2018-12-12 |
| JP2019506183A (ja) | 2019-03-07 |
| US11499184B2 (en) | 2022-11-15 |
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