ES2940246T3 - Dispositivo para la caracterización mecánica de un elemento de interés, por ejemplo, un ovocito - Google Patents
Dispositivo para la caracterización mecánica de un elemento de interés, por ejemplo, un ovocito Download PDFInfo
- Publication number
- ES2940246T3 ES2940246T3 ES18715211T ES18715211T ES2940246T3 ES 2940246 T3 ES2940246 T3 ES 2940246T3 ES 18715211 T ES18715211 T ES 18715211T ES 18715211 T ES18715211 T ES 18715211T ES 2940246 T3 ES2940246 T3 ES 2940246T3
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Links
- 238000012512 characterization method Methods 0.000 title claims abstract description 41
- 210000000287 oocyte Anatomy 0.000 title claims abstract description 26
- 230000005291 magnetic effect Effects 0.000 claims abstract description 102
- 238000013519 translation Methods 0.000 claims abstract description 30
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 238000006073 displacement reaction Methods 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 26
- 210000004027 cell Anatomy 0.000 claims description 21
- 230000006835 compression Effects 0.000 claims description 16
- 238000007906 compression Methods 0.000 claims description 16
- 238000012423 maintenance Methods 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 6
- 230000005484 gravity Effects 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 3
- 201000011510 cancer Diseases 0.000 claims description 3
- 238000007373 indentation Methods 0.000 abstract description 7
- 239000002609 medium Substances 0.000 description 13
- 238000005259 measurement Methods 0.000 description 10
- 210000000056 organ Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 230000003287 optical effect Effects 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 3
- 238000004590 computer program Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 210000000805 cytoplasm Anatomy 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000005415 magnetization Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 238000004422 calculation algorithm Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005294 ferromagnetic effect Effects 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/40—Investigating hardness or rebound hardness
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/06—Magnetic means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N3/40—Investigating hardness or rebound hardness
- G01N3/42—Investigating hardness or rebound hardness by performing impressions under a steady load by indentors, e.g. sphere, pyramid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N2203/0058—Kind of property studied
- G01N2203/0076—Hardness, compressibility or resistance to crushing
- G01N2203/0078—Hardness, compressibility or resistance to crushing using indentation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N2203/0058—Kind of property studied
- G01N2203/0076—Hardness, compressibility or resistance to crushing
- G01N2203/0085—Compressibility
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N2203/0058—Kind of property studied
- G01N2203/0076—Hardness, compressibility or resistance to crushing
- G01N2203/0087—Resistance to crushing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N2203/0058—Kind of property studied
- G01N2203/0089—Biorheological properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
- G01N2203/02—Details not specific for a particular testing method
- G01N2203/026—Specifications of the specimen
- G01N2203/0286—Miniature specimen; Testing on microregions of a specimen
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Sustainable Development (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1752330A FR3064359B1 (fr) | 2017-03-21 | 2017-03-21 | Dispositif pour la caracterisation mecanique d'un element d'interet par exemple un ovocyte |
| PCT/FR2018/050670 WO2018172688A1 (fr) | 2017-03-21 | 2018-03-20 | Dispositif pour la caracterisation mecanique d'un element d'interet par exemple un ovocyte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2940246T3 true ES2940246T3 (es) | 2023-05-04 |
Family
ID=58779177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18715211T Active ES2940246T3 (es) | 2017-03-21 | 2018-03-20 | Dispositivo para la caracterización mecánica de un elemento de interés, por ejemplo, un ovocito |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11603516B2 (https=) |
| EP (1) | EP3602000B1 (https=) |
| JP (1) | JP7227216B2 (https=) |
| CN (1) | CN110621977B (https=) |
| CA (1) | CA3057244A1 (https=) |
| ES (1) | ES2940246T3 (https=) |
| FR (1) | FR3064359B1 (https=) |
| WO (1) | WO2018172688A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7462181B2 (ja) * | 2019-11-29 | 2024-04-05 | 国立研究開発法人理化学研究所 | 三次元微小硬さ分布測定方法及び三次元微小硬さ分布測定システム |
| DE102021202724A1 (de) | 2021-03-19 | 2022-09-22 | Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Körperschaft des öffentlichen Rechts | Vorrichtung zur Charakterisierung von Veränderungen des Reifungszustands einer Eizelle, sowie deren Verwendung |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT390514B (de) * | 1984-03-16 | 1990-05-25 | Paar Anton Kg | Mikrohaertepruefeinrichtung |
| JPH0624710B2 (ja) * | 1985-09-18 | 1994-04-06 | オリンパス光学工業株式会社 | 微小物体操作装置 |
| US4959552A (en) * | 1988-02-09 | 1990-09-25 | Carl-Zeiss-Stiftung | Microscope arranged for measuring microscopic structures |
| JPH05322716A (ja) * | 1992-05-22 | 1993-12-07 | Shimadzu Corp | 細胞吸着用圧力制御装置 |
| US5486457A (en) * | 1993-08-25 | 1996-01-23 | Children's Medical Center Corporation | Method and system for measurement of mechanical properties of molecules and cells |
| JPH09196663A (ja) * | 1996-01-22 | 1997-07-31 | Nikon Corp | 微小物質の機械的変形特性測定方法およびその装置 |
| US6068604A (en) * | 1998-04-09 | 2000-05-30 | Smith & Nephew, Inc. | Cartilage indentor instrument |
| EP1425385B1 (en) * | 2001-08-14 | 2009-03-18 | Washington University in St. Louis | Systems and methods for screening pharmaceutical chemicals |
| WO2007072472A2 (en) * | 2005-12-19 | 2007-06-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Systems and methods for analyzing and manipulating biological samples |
| CN100570363C (zh) | 2006-05-09 | 2009-12-16 | 重庆大学 | 细胞力学周期加载系统 |
| WO2008105919A2 (en) * | 2006-08-23 | 2008-09-04 | The Regents Of The University Of California | Nanomechanical characterization of cellular activity |
| CN100514059C (zh) | 2006-09-22 | 2009-07-15 | 重庆大学 | 正弦拉伸细胞加载装置 |
| EP2263081A1 (en) * | 2008-04-04 | 2010-12-22 | Koninklijke Philips Electronics N.V. | Device and method for mechanically deforming cells |
| JP5710135B2 (ja) * | 2010-03-18 | 2015-04-30 | 章博 挾間 | 顕微授精装置、顕微授精用のプローブおよび顕微授精方法 |
| WO2012046089A1 (en) * | 2010-10-04 | 2012-04-12 | Dna-Technology Jsc | Magnetic tissue grinding |
| FR2984633B1 (fr) * | 2011-12-16 | 2015-11-06 | F Q N K | Actionneur electromagnetique |
| CN102759481B (zh) | 2012-06-26 | 2014-12-10 | 上海中医药大学附属岳阳中西医结合医院 | 一种多细胞的力学模拟实验平台 |
| JP6241338B2 (ja) * | 2014-03-19 | 2017-12-06 | 株式会社Ihi | 応力測定装置及び応力測定方法 |
| US9766170B2 (en) * | 2015-01-28 | 2017-09-19 | International Business Machines Corporation | Determination of young'S modulus of porous thin films using ultra-low load nano-indentation |
| US10459212B2 (en) * | 2015-07-29 | 2019-10-29 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Service | Optical trap for rheological characterization of biological materials |
-
2017
- 2017-03-21 FR FR1752330A patent/FR3064359B1/fr active Active
-
2018
- 2018-03-20 ES ES18715211T patent/ES2940246T3/es active Active
- 2018-03-20 CN CN201880029809.3A patent/CN110621977B/zh active Active
- 2018-03-20 US US16/495,918 patent/US11603516B2/en active Active
- 2018-03-20 CA CA3057244A patent/CA3057244A1/fr active Pending
- 2018-03-20 WO PCT/FR2018/050670 patent/WO2018172688A1/fr not_active Ceased
- 2018-03-20 EP EP18715211.1A patent/EP3602000B1/fr active Active
- 2018-03-20 JP JP2020501848A patent/JP7227216B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3602000B1 (fr) | 2022-12-28 |
| JP2020516908A (ja) | 2020-06-11 |
| FR3064359A1 (fr) | 2018-09-28 |
| EP3602000A1 (fr) | 2020-02-05 |
| US11603516B2 (en) | 2023-03-14 |
| WO2018172688A1 (fr) | 2018-09-27 |
| CN110621977A (zh) | 2019-12-27 |
| CN110621977B (zh) | 2023-08-01 |
| JP7227216B2 (ja) | 2023-02-21 |
| US20200131464A1 (en) | 2020-04-30 |
| CA3057244A1 (fr) | 2018-09-27 |
| FR3064359B1 (fr) | 2021-04-16 |
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