CN110621977B - 用于机械地表征诸如卵母细胞的感兴趣元件的设备 - Google Patents

用于机械地表征诸如卵母细胞的感兴趣元件的设备 Download PDF

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Publication number
CN110621977B
CN110621977B CN201880029809.3A CN201880029809A CN110621977B CN 110621977 B CN110621977 B CN 110621977B CN 201880029809 A CN201880029809 A CN 201880029809A CN 110621977 B CN110621977 B CN 110621977B
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interest
creasing
magnetic
magnetic field
horizontal direction
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Chinese (zh)
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CN110621977A (zh
Inventor
J·阿巴迪
R·加纳
E·皮亚特
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National Higher Machinery And Micro Technology School
University Franche Comte
Centre National de la Recherche Scientifique CNRS
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National Higher Machinery And Micro Technology School
University Franche Comte
Centre National de la Recherche Scientifique CNRS
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/06—Magnetic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/40—Investigating hardness or rebound hardness
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/40—Investigating hardness or rebound hardness
    • G01N3/42—Investigating hardness or rebound hardness by performing impressions under a steady load by indentors, e.g. sphere, pyramid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0076—Hardness, compressibility or resistance to crushing
    • G01N2203/0078—Hardness, compressibility or resistance to crushing using indentation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0076—Hardness, compressibility or resistance to crushing
    • G01N2203/0085—Compressibility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0076—Hardness, compressibility or resistance to crushing
    • G01N2203/0087—Resistance to crushing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058—Kind of property studied
    • G01N2203/0089—Biorheological properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02—Details not specific for a particular testing method
    • G01N2203/026—Specifications of the specimen
    • G01N2203/0286—Miniature specimen; Testing on microregions of a specimen

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
CN201880029809.3A 2017-03-21 2018-03-20 用于机械地表征诸如卵母细胞的感兴趣元件的设备 Active CN110621977B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1752330A FR3064359B1 (fr) 2017-03-21 2017-03-21 Dispositif pour la caracterisation mecanique d'un element d'interet par exemple un ovocyte
FR1752330 2017-03-21
PCT/FR2018/050670 WO2018172688A1 (fr) 2017-03-21 2018-03-20 Dispositif pour la caracterisation mecanique d'un element d'interet par exemple un ovocyte

Publications (2)

Publication Number Publication Date
CN110621977A CN110621977A (zh) 2019-12-27
CN110621977B true CN110621977B (zh) 2023-08-01

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CN201880029809.3A Active CN110621977B (zh) 2017-03-21 2018-03-20 用于机械地表征诸如卵母细胞的感兴趣元件的设备

Country Status (8)

Country Link
US (1) US11603516B2 (https=)
EP (1) EP3602000B1 (https=)
JP (1) JP7227216B2 (https=)
CN (1) CN110621977B (https=)
CA (1) CA3057244A1 (https=)
ES (1) ES2940246T3 (https=)
FR (1) FR3064359B1 (https=)
WO (1) WO2018172688A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7462181B2 (ja) * 2019-11-29 2024-04-05 国立研究開発法人理化学研究所 三次元微小硬さ分布測定方法及び三次元微小硬さ分布測定システム
DE102021202724A1 (de) 2021-03-19 2022-09-22 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Körperschaft des öffentlichen Rechts Vorrichtung zur Charakterisierung von Veränderungen des Reifungszustands einer Eizelle, sowie deren Verwendung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068604A (en) * 1998-04-09 2000-05-30 Smith & Nephew, Inc. Cartilage indentor instrument
WO2008105919A2 (en) * 2006-08-23 2008-09-04 The Regents Of The University Of California Nanomechanical characterization of cellular activity
CN101983335A (zh) * 2008-04-04 2011-03-02 皇家飞利浦电子股份有限公司 用于机械地变形细胞的装置和方法
WO2012046089A1 (en) * 2010-10-04 2012-04-12 Dna-Technology Jsc Magnetic tissue grinding

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT390514B (de) * 1984-03-16 1990-05-25 Paar Anton Kg Mikrohaertepruefeinrichtung
JPH0624710B2 (ja) * 1985-09-18 1994-04-06 オリンパス光学工業株式会社 微小物体操作装置
US4959552A (en) * 1988-02-09 1990-09-25 Carl-Zeiss-Stiftung Microscope arranged for measuring microscopic structures
JPH05322716A (ja) * 1992-05-22 1993-12-07 Shimadzu Corp 細胞吸着用圧力制御装置
US5486457A (en) * 1993-08-25 1996-01-23 Children's Medical Center Corporation Method and system for measurement of mechanical properties of molecules and cells
JPH09196663A (ja) * 1996-01-22 1997-07-31 Nikon Corp 微小物質の機械的変形特性測定方法およびその装置
EP1425385B1 (en) * 2001-08-14 2009-03-18 Washington University in St. Louis Systems and methods for screening pharmaceutical chemicals
WO2007072472A2 (en) * 2005-12-19 2007-06-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Systems and methods for analyzing and manipulating biological samples
CN100570363C (zh) 2006-05-09 2009-12-16 重庆大学 细胞力学周期加载系统
CN100514059C (zh) 2006-09-22 2009-07-15 重庆大学 正弦拉伸细胞加载装置
JP5710135B2 (ja) * 2010-03-18 2015-04-30 章博 挾間 顕微授精装置、顕微授精用のプローブおよび顕微授精方法
FR2984633B1 (fr) * 2011-12-16 2015-11-06 F Q N K Actionneur electromagnetique
CN102759481B (zh) 2012-06-26 2014-12-10 上海中医药大学附属岳阳中西医结合医院 一种多细胞的力学模拟实验平台
JP6241338B2 (ja) * 2014-03-19 2017-12-06 株式会社Ihi 応力測定装置及び応力測定方法
US9766170B2 (en) * 2015-01-28 2017-09-19 International Business Machines Corporation Determination of young'S modulus of porous thin films using ultra-low load nano-indentation
US10459212B2 (en) * 2015-07-29 2019-10-29 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Service Optical trap for rheological characterization of biological materials

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068604A (en) * 1998-04-09 2000-05-30 Smith & Nephew, Inc. Cartilage indentor instrument
WO2008105919A2 (en) * 2006-08-23 2008-09-04 The Regents Of The University Of California Nanomechanical characterization of cellular activity
CN101983335A (zh) * 2008-04-04 2011-03-02 皇家飞利浦电子股份有限公司 用于机械地变形细胞的装置和方法
WO2012046089A1 (en) * 2010-10-04 2012-04-12 Dna-Technology Jsc Magnetic tissue grinding

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dynamic monitoring of cell mechanical properties using profile microindentation;L.Guillou;《SCIENTIFIC REPORTS》;20160209;1-13 *

Also Published As

Publication number Publication date
EP3602000B1 (fr) 2022-12-28
JP2020516908A (ja) 2020-06-11
FR3064359A1 (fr) 2018-09-28
EP3602000A1 (fr) 2020-02-05
US11603516B2 (en) 2023-03-14
WO2018172688A1 (fr) 2018-09-27
CN110621977A (zh) 2019-12-27
ES2940246T3 (es) 2023-05-04
JP7227216B2 (ja) 2023-02-21
US20200131464A1 (en) 2020-04-30
CA3057244A1 (fr) 2018-09-27
FR3064359B1 (fr) 2021-04-16

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