ES2936861T3 - Inhalador - Google Patents
Inhalador Download PDFInfo
- Publication number
- ES2936861T3 ES2936861T3 ES18701295T ES18701295T ES2936861T3 ES 2936861 T3 ES2936861 T3 ES 2936861T3 ES 18701295 T ES18701295 T ES 18701295T ES 18701295 T ES18701295 T ES 18701295T ES 2936861 T3 ES2936861 T3 ES 2936861T3
- Authority
- ES
- Spain
- Prior art keywords
- inhaler
- outlet
- sectional area
- less
- inlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003814 drug Substances 0.000 claims abstract description 37
- 229940079593 drug Drugs 0.000 claims abstract description 22
- 230000005540 biological transmission Effects 0.000 claims abstract description 5
- 239000000843 powder Substances 0.000 claims description 37
- 239000002245 particle Substances 0.000 claims description 23
- 238000012360 testing method Methods 0.000 claims description 16
- 239000000126 substance Substances 0.000 claims description 6
- 230000001419 dependent effect Effects 0.000 claims description 2
- 239000007921 spray Substances 0.000 description 15
- 229940112141 dry powder inhaler Drugs 0.000 description 14
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- 239000004480 active ingredient Substances 0.000 description 9
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- 239000010419 fine particle Substances 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
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- WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 description 5
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- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 4
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- NSILVESQCSUIAJ-UHFFFAOYSA-M hexocyclium methyl sulfate Chemical compound COS([O-])(=O)=O.C1C[N+](C)(C)CCN1CC(O)(C=1C=CC=CC=1)C1CCCCC1 NSILVESQCSUIAJ-UHFFFAOYSA-M 0.000 description 3
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 239000000556 agonist Substances 0.000 description 2
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- 230000015572 biosynthetic process Effects 0.000 description 2
- GZUXJHMPEANEGY-UHFFFAOYSA-N bromomethane Chemical compound BrC GZUXJHMPEANEGY-UHFFFAOYSA-N 0.000 description 2
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- 230000000052 comparative effect Effects 0.000 description 2
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- 238000000034 method Methods 0.000 description 2
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- 230000002093 peripheral effect Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
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- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 description 1
- GKEGFOKQMZHVOW-UHFFFAOYSA-M (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide Chemical compound [Br-].C1C[N+](C)(C2)CCC1C2OC(=O)C(O)(C=1C=CC=CC=1)C1=CC=CC=C1 GKEGFOKQMZHVOW-UHFFFAOYSA-M 0.000 description 1
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- OBRNDARFFFHCGE-PERKLWIXSA-N (S,S)-formoterol fumarate Chemical compound OC(=O)\C=C\C(O)=O.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1.C1=CC(OC)=CC=C1C[C@H](C)NC[C@@H](O)C1=CC=C(O)C(NC=O)=C1 OBRNDARFFFHCGE-PERKLWIXSA-N 0.000 description 1
- PMGQWSIVQFOFOQ-BDUVBVHRSA-N (e)-but-2-enedioic acid;(2r)-2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine Chemical compound OC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCOC(C)(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 PMGQWSIVQFOFOQ-BDUVBVHRSA-N 0.000 description 1
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- G01N15/06—Investigating concentration of particle suspensions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
- G01N15/075—Investigating concentration of particle suspensions by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N2015/0042—Investigating dispersion of solids
- G01N2015/0046—Investigating dispersion of solids in gas, e.g. smoke
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1700727.9A GB201700727D0 (en) | 2017-01-16 | 2017-01-16 | Inhalers and airflow adaptors therefor |
| PCT/EP2018/051036 WO2018130727A1 (en) | 2017-01-16 | 2018-01-16 | Inhalers and airflow adaptors therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2936861T3 true ES2936861T3 (es) | 2023-03-22 |
Family
ID=58463410
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18701295T Active ES2936861T3 (es) | 2017-01-16 | 2018-01-16 | Inhalador |
| ES21174417T Active ES2988391T3 (es) | 2017-01-16 | 2018-01-16 | Método de ensayo para un inhalador de polvo seco |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES21174417T Active ES2988391T3 (es) | 2017-01-16 | 2018-01-16 | Método de ensayo para un inhalador de polvo seco |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20200179623A1 (enExample) |
| EP (6) | EP3884977B1 (enExample) |
| JP (1) | JP2020505113A (enExample) |
| KR (1) | KR20190108592A (enExample) |
| CN (1) | CN110177592B (enExample) |
| AU (1) | AU2018207234B2 (enExample) |
| CA (2) | CA3049504A1 (enExample) |
| DK (1) | DK3568181T3 (enExample) |
| EA (1) | EA039623B1 (enExample) |
| ES (2) | ES2936861T3 (enExample) |
| FI (1) | FI3568181T3 (enExample) |
| GB (1) | GB201700727D0 (enExample) |
| HU (1) | HUE061264T2 (enExample) |
| IL (1) | IL267860B2 (enExample) |
| PL (1) | PL3568181T3 (enExample) |
| PT (1) | PT3568181T (enExample) |
| WO (2) | WO2018130727A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201700727D0 (en) | 2017-01-16 | 2017-03-01 | Teva Pharma | Inhalers and airflow adaptors therefor |
| GB2614774A (en) * | 2022-07-14 | 2023-07-19 | Copley Scient Ltd | Inhaler testing apparatus |
| WO2024156752A1 (de) * | 2023-01-24 | 2024-08-02 | Microtrac Retsch Gmbh | Deagglomerationsvorrichtung und partikelmessvorrichtung |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2918A (en) | 1843-01-20 | Improvement in machinery and in the process of manufacturing metallic pipes | ||
| US408A (en) | 1837-09-25 | Machine for | ||
| DE4211475A1 (de) * | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| US6785400B1 (en) * | 1999-08-17 | 2004-08-31 | Image Therm Engineering, Inc. | Spray data acquisition system |
| TWI224513B (en) * | 2000-06-23 | 2004-12-01 | Norton Healthcare Ltd | Dose counter for medicament inhaler |
| PE20020067A1 (es) | 2000-06-23 | 2002-02-05 | Norton Healthcare Ltd | Desaglomerador para inhalador de polvo seco accionado por la respiracion |
| FI20002363A0 (fi) | 2000-10-27 | 2000-10-27 | Orion Yhtymae Oyj | Jauheinhalaattori |
| US6618127B2 (en) * | 2001-11-26 | 2003-09-09 | Patheon Inc. | Spray plume characterization system |
| GB0321607D0 (en) | 2003-09-15 | 2003-10-15 | Vectura Ltd | Manufacture of pharmaceutical compositions |
| GB0420513D0 (en) * | 2004-09-15 | 2004-10-20 | Optinose As | Powder delivery devices |
| GB0427856D0 (en) | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Maniflod for use in medicament dispenser |
| US7219664B2 (en) * | 2005-04-28 | 2007-05-22 | Kos Life Sciences, Inc. | Breath actuated inhaler |
| WO2009029027A1 (en) * | 2007-08-24 | 2009-03-05 | Astrazeneca Ab | Breath- triggered inhaler |
| CA2992927A1 (en) * | 2009-03-18 | 2010-09-23 | Mannkind Corporation | Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution |
| GB0919465D0 (en) * | 2009-11-06 | 2009-12-23 | Norton Healthcare Ltd | Airflow adaptor for a breath-actuated dry powder inhaler |
| DE102009052267A1 (de) | 2009-11-06 | 2011-05-12 | Georg Ortner | Verfahren und Vorrichtung zur Erzeugung eines Duftluftstroms |
| WO2012078804A1 (en) * | 2010-12-07 | 2012-06-14 | Respira Therapeutics, Inc. | Dry powder inhaler |
| US20120234320A1 (en) * | 2011-03-17 | 2012-09-20 | O'ferrell Zachary W | Metered Dose Inhaler Port for Ventilated Patients |
| US20140002667A1 (en) * | 2011-03-25 | 2014-01-02 | Joseph M. Cheben | Differential Infrared Imager for Gas Plume Detection |
| CN107376071B (zh) * | 2011-05-09 | 2021-07-09 | 英倍尔药业股份有限公司 | 用于将化合物递送到使用者的上部嗅觉区的喷嘴 |
| US12491325B2 (en) * | 2013-08-22 | 2025-12-09 | Aptargroup, Inc. | Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity |
| US11278682B2 (en) * | 2014-11-09 | 2022-03-22 | Sipnose Ltd. | Device and method for aerosolized delivery of substance to a natural orifice of the body |
| US20150092189A1 (en) * | 2013-10-01 | 2015-04-02 | Innovasystems, Inc. | Spray analysis system and method |
| PL3054920T3 (pl) * | 2013-10-07 | 2021-07-05 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalator suchego proszku |
| US11013682B2 (en) * | 2016-04-25 | 2021-05-25 | Technion Research & Development Foundation Limited | Targeted delivery of aerosols of magnetized active agents |
| GB201700727D0 (en) | 2017-01-16 | 2017-03-01 | Teva Pharma | Inhalers and airflow adaptors therefor |
-
2017
- 2017-01-16 GB GBGB1700727.9A patent/GB201700727D0/en not_active Ceased
-
2018
- 2018-01-16 US US16/477,380 patent/US20200179623A1/en not_active Abandoned
- 2018-01-16 EP EP21174417.2A patent/EP3884977B1/en active Active
- 2018-01-16 WO PCT/EP2018/051036 patent/WO2018130727A1/en not_active Ceased
- 2018-01-16 EP EP18700589.7A patent/EP3568180A1/en not_active Withdrawn
- 2018-01-16 US US16/476,390 patent/US11969544B2/en active Active
- 2018-01-16 CN CN201880007039.2A patent/CN110177592B/zh active Active
- 2018-01-16 CA CA3049504A patent/CA3049504A1/en not_active Withdrawn
- 2018-01-16 IL IL267860A patent/IL267860B2/en unknown
- 2018-01-16 DK DK18701295.0T patent/DK3568181T3/da active
- 2018-01-16 EA EA201991706A patent/EA039623B1/ru unknown
- 2018-01-16 AU AU2018207234A patent/AU2018207234B2/en not_active Ceased
- 2018-01-16 HU HUE18701295A patent/HUE061264T2/hu unknown
- 2018-01-16 PL PL18701295.0T patent/PL3568181T3/pl unknown
- 2018-01-16 JP JP2019538350A patent/JP2020505113A/ja active Pending
- 2018-01-16 ES ES18701295T patent/ES2936861T3/es active Active
- 2018-01-16 EP EP21174424.8A patent/EP3884979A1/en not_active Withdrawn
- 2018-01-16 EP EP18701295.0A patent/EP3568181B1/en active Active
- 2018-01-16 EP EP21174419.8A patent/EP3884978A1/en not_active Withdrawn
- 2018-01-16 KR KR1020197023286A patent/KR20190108592A/ko not_active Ceased
- 2018-01-16 PT PT187012950T patent/PT3568181T/pt unknown
- 2018-01-16 ES ES21174417T patent/ES2988391T3/es active Active
- 2018-01-16 EP EP22213233.4A patent/EP4169557A1/en not_active Withdrawn
- 2018-01-16 WO PCT/EP2018/051023 patent/WO2018130723A1/en not_active Ceased
- 2018-01-16 FI FIEP18701295.0T patent/FI3568181T3/fi active
- 2018-01-16 CA CA3049297A patent/CA3049297A1/en not_active Withdrawn
-
2021
- 2021-06-02 US US17/337,327 patent/US20210283349A1/en not_active Abandoned
- 2021-06-02 US US17/337,325 patent/US11771851B2/en active Active
- 2021-06-02 US US17/337,328 patent/US20210283350A1/en not_active Abandoned
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