AU2018207234B2 - Inhalers and airflow adaptors therefor - Google Patents

Inhalers and airflow adaptors therefor Download PDF

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Publication number
AU2018207234B2
AU2018207234B2 AU2018207234A AU2018207234A AU2018207234B2 AU 2018207234 B2 AU2018207234 B2 AU 2018207234B2 AU 2018207234 A AU2018207234 A AU 2018207234A AU 2018207234 A AU2018207234 A AU 2018207234A AU 2018207234 B2 AU2018207234 B2 AU 2018207234B2
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AU
Australia
Prior art keywords
inhaler
sectional area
outlet
air
cross
Prior art date
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Application number
AU2018207234A
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English (en)
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AU2018207234A1 (en
Inventor
Daniel R. Buck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Waterford Ltd
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Norton Waterford Ltd
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Application filed by Norton Waterford Ltd filed Critical Norton Waterford Ltd
Publication of AU2018207234A1 publication Critical patent/AU2018207234A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • G01N15/075—Investigating concentration of particle suspensions by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0042—Investigating dispersion of solids
    • G01N2015/0046—Investigating dispersion of solids in gas, e.g. smoke

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2018207234A 2017-01-16 2018-01-16 Inhalers and airflow adaptors therefor Active AU2018207234B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1700727.9 2017-01-16
GBGB1700727.9A GB201700727D0 (en) 2017-01-16 2017-01-16 Inhalers and airflow adaptors therefor
PCT/EP2018/051036 WO2018130727A1 (en) 2017-01-16 2018-01-16 Inhalers and airflow adaptors therefor

Publications (2)

Publication Number Publication Date
AU2018207234A1 AU2018207234A1 (en) 2019-07-11
AU2018207234B2 true AU2018207234B2 (en) 2023-11-02

Family

ID=58463410

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018207234A Active AU2018207234B2 (en) 2017-01-16 2018-01-16 Inhalers and airflow adaptors therefor

Country Status (17)

Country Link
US (5) US20200179623A1 (enExample)
EP (6) EP3884979A1 (enExample)
JP (1) JP2020505113A (enExample)
KR (1) KR20190108592A (enExample)
CN (1) CN110177592B (enExample)
AU (1) AU2018207234B2 (enExample)
CA (2) CA3049297A1 (enExample)
DK (1) DK3568181T3 (enExample)
EA (1) EA039623B1 (enExample)
ES (2) ES2936861T3 (enExample)
FI (1) FI3568181T3 (enExample)
GB (1) GB201700727D0 (enExample)
HU (1) HUE061264T2 (enExample)
IL (1) IL267860B2 (enExample)
PL (1) PL3568181T3 (enExample)
PT (1) PT3568181T (enExample)
WO (2) WO2018130727A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201700727D0 (en) 2017-01-16 2017-03-01 Teva Pharma Inhalers and airflow adaptors therefor
GB2614774A (en) * 2022-07-14 2023-07-19 Copley Scient Ltd Inhaler testing apparatus
WO2024156752A1 (de) * 2023-01-24 2024-08-02 Microtrac Retsch Gmbh Deagglomerationsvorrichtung und partikelmessvorrichtung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5301666A (en) * 1991-12-14 1994-04-12 Asta Medica Aktiengesellschaft Powder inhaler
WO2009029027A1 (en) * 2007-08-24 2009-03-05 Astrazeneca Ab Breath- triggered inhaler
US20110108030A1 (en) * 2009-11-06 2011-05-12 Norton Healthcare Ltd. Airflow adaptor for a breath-actuated dry powder inhaler
WO2012078804A1 (en) * 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler

Family Cites Families (23)

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US408A (en) 1837-09-25 Machine for
US2918A (en) 1843-01-20 Improvement in machinery and in the process of manufacturing metallic pipes
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6785400B1 (en) * 1999-08-17 2004-08-31 Image Therm Engineering, Inc. Spray data acquisition system
TWI224511B (en) 2000-06-23 2004-12-01 Norton Healthcare Ltd De-agglomerator for breath-actuated dry powder inhaler
PE20020075A1 (es) * 2000-06-23 2002-02-05 Norton Healthcare Ltd Dispositivo contador de dosis para inhalador de medicamento
FI20002363A0 (fi) * 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
US6618127B2 (en) * 2001-11-26 2003-09-09 Patheon Inc. Spray plume characterization system
GB0321607D0 (en) 2003-09-15 2003-10-15 Vectura Ltd Manufacture of pharmaceutical compositions
GB0420513D0 (en) * 2004-09-15 2004-10-20 Optinose As Powder delivery devices
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
US7219664B2 (en) * 2005-04-28 2007-05-22 Kos Life Sciences, Inc. Breath actuated inhaler
US8508732B2 (en) * 2009-03-18 2013-08-13 Mannkind Corporation Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution
DE102009052267A1 (de) 2009-11-06 2011-05-12 Georg Ortner Verfahren und Vorrichtung zur Erzeugung eines Duftluftstroms
US20120234320A1 (en) * 2011-03-17 2012-09-20 O'ferrell Zachary W Metered Dose Inhaler Port for Ventilated Patients
EP2689457A4 (en) * 2011-03-25 2014-10-08 Exxonmobil Upstream Res Co DIFFERENTIAL INFRARED IMAGING APPARATUS FOR DETECTING GAS BANNERS
RU2741249C2 (ru) * 2011-05-09 2021-01-22 Импел Ньюрофарма Инк. Наконечники для назальной доставки лекарственных средств
US11278682B2 (en) * 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US12491325B2 (en) * 2013-08-22 2025-12-09 Aptargroup, Inc. Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity
US20150092189A1 (en) * 2013-10-01 2015-04-02 Innovasystems, Inc. Spray analysis system and method
MX374870B (es) * 2013-10-07 2025-03-06 Teva Branded Pharmaceutical Products R&D Inc Inhalador de polvo seco.
US11013682B2 (en) * 2016-04-25 2021-05-25 Technion Research & Development Foundation Limited Targeted delivery of aerosols of magnetized active agents
GB201700727D0 (en) 2017-01-16 2017-03-01 Teva Pharma Inhalers and airflow adaptors therefor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5301666A (en) * 1991-12-14 1994-04-12 Asta Medica Aktiengesellschaft Powder inhaler
WO2009029027A1 (en) * 2007-08-24 2009-03-05 Astrazeneca Ab Breath- triggered inhaler
US20110108030A1 (en) * 2009-11-06 2011-05-12 Norton Healthcare Ltd. Airflow adaptor for a breath-actuated dry powder inhaler
WO2012078804A1 (en) * 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler

Also Published As

Publication number Publication date
US11969544B2 (en) 2024-04-30
EA039623B1 (ru) 2022-02-17
CN110177592B (zh) 2023-03-31
GB201700727D0 (en) 2017-03-01
KR20190108592A (ko) 2019-09-24
JP2020505113A (ja) 2020-02-20
US20210283350A1 (en) 2021-09-16
EP3568181B1 (en) 2022-12-14
EP3568181A1 (en) 2019-11-20
EP3884977B1 (en) 2024-07-17
WO2018130727A1 (en) 2018-07-19
EA201991706A1 (ru) 2019-12-30
IL267860B1 (en) 2023-10-01
HUE061264T2 (hu) 2023-09-28
EP3568180A1 (en) 2019-11-20
US20210283348A1 (en) 2021-09-16
CA3049504A1 (en) 2018-07-19
ES2988391T3 (es) 2024-11-20
IL267860A (en) 2019-09-26
EP3884978A1 (en) 2021-09-29
EP4169557A1 (en) 2023-04-26
ES2936861T3 (es) 2023-03-22
WO2018130723A1 (en) 2018-07-19
DK3568181T3 (da) 2023-01-30
US20210283349A1 (en) 2021-09-16
IL267860B2 (en) 2024-02-01
US20200179623A1 (en) 2020-06-11
EP3884977A1 (en) 2021-09-29
PT3568181T (pt) 2023-02-01
AU2018207234A1 (en) 2019-07-11
US11771851B2 (en) 2023-10-03
PL3568181T3 (pl) 2023-03-27
CA3049297A1 (en) 2018-07-19
CN110177592A (zh) 2019-08-27
EP3884979A1 (en) 2021-09-29
US20200129711A1 (en) 2020-04-30
FI3568181T3 (fi) 2023-01-31

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