ES293351A1 - Procedure for the elaboration of new esters of the cycle-alcanol-carboxylic acid basically replaced (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of new esters of the cycloalkanol carboxylic acid of the general formula I: ** (See formula) ** wherein A represents an optionally substituted alkylene radical, preferably with more than three carbon atoms of the alkylene chain, which substituents, optionally incorporating at least one carbon atom of the alkylene chain, can form a ring, for example a ring of benzene bound by ortho-fusion or a ring of espirano, X is a radical of alkylene, lower, optionally substituted, particularly with up to 5 carbon atoms, Y is a basic radical optionally substituted, preferably with a tertiary nitrogen atom , in particular a dialkyl amino group or an optionally substituted heterocyclic radical, such as a pyrrolidino, piperidino, morpholino, tetrahydropyridino, hexamethylene imino or decahydro quinolinino radical, and R 'is an optionally substituted alkyl radical, a radical of optionally substituted aryl, an optionally substituted aralkyl or aralkenyl radical or a substituted alkylene radical by a radical containing a hetero-atom, for example an S-alkyl, O-alkyl or dialkyl-amino radical or a heterocyclic radical, such as piperidino, which may optionally contain a double bond, with the exception of the 2-ethyl ester beta-diethyl-amino-ethyl-cyclopentanol-carboxylic acid and its salts, characterized in that esters of the cyclo-alkanone-carboxylic acid of the general formula II are reduced: ** (See formula) ** wherein A, R ', X and Y have the meaning given above, in a manner known per se, to the corresponding hydroxy compounds and, if desired, converting the compounds of the general formula I into their salts or releasing the same of the latter. (Machine-translation by Google Translate, not legally binding)