ES400917A1 - Aminoisoquinolines - Google Patents
AminoisoquinolinesInfo
- Publication number
- ES400917A1 ES400917A1 ES400917A ES400917A ES400917A1 ES 400917 A1 ES400917 A1 ES 400917A1 ES 400917 A ES400917 A ES 400917A ES 400917 A ES400917 A ES 400917A ES 400917 A1 ES400917 A1 ES 400917A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- lower alkyl
- hydrogen
- equal
- aminoisoquinolines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OSILBMSORKFRTB-UHFFFAOYSA-N isoquinolin-1-amine Chemical class C1=CC=C2C(N)=NC=CC2=C1 OSILBMSORKFRTB-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- -1 carboalkoxyalkyl Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Procedure, to prepare dihydro-2-aminoisoquinolines, of general formula: **(See formula)** where X and Y are different and represents hydrogen or oxygen; R and R1 are independently selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl, lower aminoalkyl, mono and dialkyl (lower) amino-lower alkyl, carboxy lower alkyl, carboalkoxyalkyl, cycloalkyl, aryl, aralkyl, acyl derived from one aliphatic, aromatic, or heterocyclic carboxylic acid moiety, carbamyl, thiocarbamyl, arylcarbamyl, arylthiocarbamyl, guanyl, arylsulfonyl, alkylsulfonyl, haloalkylsulfonyl; or R and R1, taken together with the adjacent nitrogen atom, represent an aralkylideneamino, alkylideneamino, carboxyalkylideneamino, carbalkoxyalkylideneamino, cycloalkylideneamino radical or form a 5- to 7-atom heterocyclic ring; and in which formula only one of R and R1 can be hydrogen, characterized in that it comprises heating a solution of a hydrazide of formula: **(See formula)** in which R and R1 are defined as above and m and n can assume the following combinations of meanings: a) m is equal to n equal to 1, b) m is 0 and n is 2, in an inert organic solvent, in the presence of a strong base as an acid acceptor. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2193171 | 1971-03-18 | ||
| IT3300671A IT1044903B (en) | 1971-12-28 | 1971-12-28 | AMINOISCOHINOLINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES400917A1 true ES400917A1 (en) | 1975-09-01 |
Family
ID=26328050
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES400890A Expired ES400890A1 (en) | 1971-03-18 | 1972-03-17 | Aminoisoquinolines |
| ES400917A Expired ES400917A1 (en) | 1971-03-18 | 1972-03-18 | Aminoisoquinolines |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES400890A Expired ES400890A1 (en) | 1971-03-18 | 1972-03-17 | Aminoisoquinolines |
Country Status (14)
| Country | Link |
|---|---|
| JP (2) | JPS4935629B1 (en) |
| AR (6) | AR204975A1 (en) |
| BE (1) | BE780885A (en) |
| CH (3) | CH545788A (en) |
| DE (1) | DE2212693A1 (en) |
| DK (1) | DK132622C (en) |
| ES (2) | ES400890A1 (en) |
| FI (1) | FI50875C (en) |
| FR (1) | FR2130362B1 (en) |
| GB (1) | GB1377310A (en) |
| HU (1) | HU163899B (en) |
| IL (1) | IL38792A (en) |
| NL (1) | NL146809B (en) |
| SE (1) | SE382810B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RO66059A (en) * | 1973-05-25 | 1981-05-30 | Gruppo Lepetit Spa,It | PROCESS FOR OBTAINING TRIAZOLOCHINOLINE DERIVATIVES |
| US4075341A (en) * | 1974-05-24 | 1978-02-21 | Gruppo Lepetit S.P.A. | 2-Substituted phenyl-5-triazols [5,1-a] isoquinoline compounds |
| KR101722112B1 (en) * | 2016-04-26 | 2017-03-31 | (특수법인)한국전파진흥협회 | Apparatus for granting Certification Code, Certification System for Used Mobile Phones, and Certification Method using the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3037984A (en) * | 1960-01-27 | 1962-06-05 | Lakeside Lab Inc | Derivatives of n-amino-1, 2, 3, 4-tetrahydroisoquinoline |
-
1972
- 1972-01-01 AR AR244807A patent/AR204975A1/en active
- 1972-02-18 IL IL38792A patent/IL38792A/en unknown
- 1972-02-28 GB GB902572A patent/GB1377310A/en not_active Expired
- 1972-03-08 AR AR240848A patent/AR199274A1/en active
- 1972-03-08 FI FI720608A patent/FI50875C/en active
- 1972-03-10 DK DK110872A patent/DK132622C/en active
- 1972-03-16 CH CH410573A patent/CH545788A/xx not_active IP Right Cessation
- 1972-03-16 CH CH389372A patent/CH559726A5/xx not_active IP Right Cessation
- 1972-03-16 DE DE19722212693 patent/DE2212693A1/en active Pending
- 1972-03-16 CH CH410673A patent/CH545789A/xx not_active IP Right Cessation
- 1972-03-17 ES ES400890A patent/ES400890A1/en not_active Expired
- 1972-03-17 BE BE780885A patent/BE780885A/en unknown
- 1972-03-17 NL NL727203638A patent/NL146809B/en unknown
- 1972-03-17 FR FR7209347A patent/FR2130362B1/fr not_active Expired
- 1972-03-17 JP JP47027324A patent/JPS4935629B1/ja active Pending
- 1972-03-17 SE SE7203496A patent/SE382810B/en unknown
- 1972-03-17 HU HULE642A patent/HU163899B/hu unknown
- 1972-03-18 ES ES400917A patent/ES400917A1/en not_active Expired
-
1974
- 1974-02-11 AR AR252282A patent/AR199605A1/en active
- 1974-02-11 AR AR252280A patent/AR202290A1/en active
- 1974-02-11 AR AR252279A patent/AR201569A1/en active
- 1974-02-11 AR AR252281A patent/AR202206A1/en active
- 1974-02-13 JP JP49017519A patent/JPS49124077A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CH545788A (en) | 1974-02-15 |
| FR2130362B1 (en) | 1975-06-20 |
| AR201569A1 (en) | 1975-03-31 |
| DE2212693A1 (en) | 1972-10-05 |
| ES400890A1 (en) | 1975-01-16 |
| SE382810B (en) | 1976-02-16 |
| NL7203638A (en) | 1972-09-20 |
| AR199605A1 (en) | 1974-09-13 |
| CH559726A5 (en) | 1975-03-14 |
| AR199274A1 (en) | 1974-08-23 |
| JPS4935629B1 (en) | 1974-09-25 |
| FR2130362A1 (en) | 1972-11-03 |
| DK132622B (en) | 1976-01-12 |
| AR202206A1 (en) | 1975-05-23 |
| FI50875C (en) | 1976-08-10 |
| HU163899B (en) | 1973-11-28 |
| DK132622C (en) | 1976-06-08 |
| GB1377310A (en) | 1974-12-11 |
| CH545789A (en) | 1974-02-15 |
| IL38792A0 (en) | 1972-04-27 |
| NL146809B (en) | 1975-08-15 |
| AR204975A1 (en) | 1976-03-31 |
| JPS49124077A (en) | 1974-11-27 |
| FI50875B (en) | 1976-04-30 |
| BE780885A (en) | 1972-07-17 |
| AR202290A1 (en) | 1975-05-30 |
| IL38792A (en) | 1976-06-30 |
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