ES2925950T3 - Composiciones para la tuberculosis y procedimientos de uso de las mismas - Google Patents

Composiciones para la tuberculosis y procedimientos de uso de las mismas Download PDF

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Publication number
ES2925950T3
ES2925950T3 ES14817274T ES14817274T ES2925950T3 ES 2925950 T3 ES2925950 T3 ES 2925950T3 ES 14817274 T ES14817274 T ES 14817274T ES 14817274 T ES14817274 T ES 14817274T ES 2925950 T3 ES2925950 T3 ES 2925950T3
Authority
ES
Spain
Prior art keywords
mtb
antigen
antigens
fusion protein
rv1733c
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14817274T
Other languages
English (en)
Spanish (es)
Inventor
Ravi Anantha
Nathalie Cadieux
Thomas G Evans
Michele Stone
Barry Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Int Aids Vaccine Initiative Inc
International AIDS Vaccine Initiative Inc
Original Assignee
Int Aids Vaccine Initiative Inc
International AIDS Vaccine Initiative Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Aids Vaccine Initiative Inc, International AIDS Vaccine Initiative Inc filed Critical Int Aids Vaccine Initiative Inc
Application granted granted Critical
Publication of ES2925950T3 publication Critical patent/ES2925950T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES14817274T 2013-06-25 2014-06-24 Composiciones para la tuberculosis y procedimientos de uso de las mismas Active ES2925950T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361838872P 2013-06-25 2013-06-25
PCT/US2014/043889 WO2014210018A1 (en) 2013-06-25 2014-06-24 Tuberculosis compositions and methods of using the same

Publications (1)

Publication Number Publication Date
ES2925950T3 true ES2925950T3 (es) 2022-10-20

Family

ID=52111114

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14817274T Active ES2925950T3 (es) 2013-06-25 2014-06-24 Composiciones para la tuberculosis y procedimientos de uso de las mismas

Country Status (7)

Country Link
US (4) US10266574B2 (cg-RX-API-DMAC7.html)
EP (2) EP4176897A1 (cg-RX-API-DMAC7.html)
JP (2) JP6554095B2 (cg-RX-API-DMAC7.html)
CN (1) CN105431166B (cg-RX-API-DMAC7.html)
ES (1) ES2925950T3 (cg-RX-API-DMAC7.html)
WO (1) WO2014210018A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201509262B (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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KR20150058152A (ko) * 2012-07-10 2015-05-28 트랜스진 에스아이 마이코박테리아 항원 백신
JP6554095B2 (ja) 2013-06-25 2019-07-31 アエラス グローバル ティービー ワクチン ファウンデーション 結核組成物及びそれを使用する方法
CN106103471B (zh) 2014-01-09 2020-01-07 特兰斯吉恩股份有限公司 异源寡聚分枝杆菌抗原的融合
WO2016120489A2 (en) * 2015-02-01 2016-08-04 Theravectys Lentiviral vectors for expression of mycobacterium tuberculosis antigens
CA3027995A1 (en) * 2016-06-16 2017-12-21 Aeras Tuberculosis compositions and methods of treating or preventing tuberculosis
AU2017280065B2 (en) * 2016-06-22 2021-07-01 International Aids Vaccine Initiative, Inc. Recombinant cytomegalovirus vectors as vaccines for tuberculosis
ES2950436T3 (es) 2016-12-14 2023-10-10 Becton Dickinson Co Métodos y composiciones para obtener una valoración de tuberculosis en un sujeto
CN108239660B (zh) * 2016-12-26 2021-08-10 上海生物制品研究所有限责任公司 一种重组结核病疫苗,其制备方法及应用
WO2019079155A1 (en) 2017-10-17 2019-04-25 International Aids Vaccine Initiative, Inc. CASSETTES OF ANTIGENS OF TUBERCULOSIS
KR102135334B1 (ko) * 2018-12-19 2020-07-17 대한민국 결핵 다가 항원을 발현하는 재조합 아데노 바이러스 및 이를 포함하는 결핵 예방용 조성물
CN116327906A (zh) * 2021-12-22 2023-06-27 中国人民解放军总医院第八医学中心 一种结核分枝杆菌串联dna疫苗w545及其制备方法与应用
CN117777259B (zh) * 2024-02-23 2024-06-07 上海科新生物技术股份有限公司 检测结核感染的抗原组合物、试剂盒及其应用

Family Cites Families (21)

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US21579A (en) 1858-09-21 Rotary valve fob steam-engines
IL105914A0 (en) 1992-06-04 1993-10-20 Univ California Methods and compositions for in vivo gene therapy
US5593972A (en) 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
CA2153593C (en) 1993-01-26 2010-04-13 David B. Weiner Compositions and methods for delivery of genetic material
US5962428A (en) 1995-03-30 1999-10-05 Apollon, Inc. Compositions and methods for delivery of genetic material
KR101329323B1 (ko) 2004-12-01 2013-11-14 아에라스 글로벌 티비 백신 파운데이션 엔도솜을 이탈하는 능력이 보강된 재조합 비씨지 균주
EP2380589A3 (en) 2005-06-23 2012-09-12 Statens Serum Institut Improved tuberculosis vaccines
BRPI0620693A2 (pt) * 2005-12-15 2016-12-13 Aeras Global Tb Vaccine Found método para suscitar uma resposta imune tanto sistêmica como de mucosa a mycobacteria viva atenuada ou antígenos micobacterianos em um hospedeiro
PL2136836T3 (pl) * 2007-04-04 2017-07-31 Infectious Disease Research Institute Kompozycje immunogenne zawierające polipeptydy prątka gruźlicy i produkty ich fuzji
US7670609B2 (en) 2007-11-27 2010-03-02 Aeras Global Tb Vaccine Foundation Recombinant BCG tuberculosis vaccine designed to elicit immune responses to Mycobacterium tuberculosis in all physiological stages of infection and disease
US8361482B2 (en) 2007-11-27 2013-01-29 Aeras Global Tb Vaccine Foundation Recombinant BCG tuberculosis vaccine designed to elicit immune responses to mycobacterium tuberculosis in all physiological stages of infection and disease
CN101289496B (zh) * 2008-05-30 2011-06-29 中国医学科学院医学生物学研究所 能激发机体抗结核杆菌的保护性免疫反应的抗原表位筛选方法及用途
BRPI1011902A2 (pt) * 2009-04-28 2019-09-24 Univ Johns Hopkins composições e métodos para potencialização de respostas imunes antígeno-específicas
GB0918154D0 (en) * 2009-10-16 2009-12-02 Isis Innovation Mycobacterial vaccines
BR112012003380A2 (pt) * 2009-11-02 2016-11-16 Biocomo Co Ltd vacina contra tuberculose do tipo spray intranasal usando um vetor de paramyxovírus.
HRP20161608T1 (hr) * 2010-01-27 2017-01-13 Glaxosmithkline Biologicals Sa Modificirani tuberkulozni antigeni
US20120003256A1 (en) 2010-03-01 2012-01-05 Huiling Han Tuberculosis antigens, immunogenic compositions, diagnostics and methods related to the same
GB201008512D0 (en) * 2010-05-21 2010-07-07 Health Prot Agency Mycobacterial antigen composition
KR20150058152A (ko) * 2012-07-10 2015-05-28 트랜스진 에스아이 마이코박테리아 항원 백신
JP6554095B2 (ja) * 2013-06-25 2019-07-31 アエラス グローバル ティービー ワクチン ファウンデーション 結核組成物及びそれを使用する方法
CN104474538A (zh) 2014-08-13 2015-04-01 华中科技大学 一种重组卡介苗

Also Published As

Publication number Publication date
EP3013364A4 (en) 2017-05-31
US10266574B2 (en) 2019-04-23
CN105431166B (zh) 2020-09-18
JP6554095B2 (ja) 2019-07-31
US20140377300A1 (en) 2014-12-25
ZA201509262B (en) 2017-11-29
US20210371474A1 (en) 2021-12-02
CN105431166A (zh) 2016-03-23
EP4176897A1 (en) 2023-05-10
US20190322709A1 (en) 2019-10-24
JP7269806B2 (ja) 2023-05-09
US20240101612A1 (en) 2024-03-28
EP3013364B1 (en) 2022-08-03
EP3013364A1 (en) 2016-05-04
JP2016529223A (ja) 2016-09-23
US11787842B2 (en) 2023-10-17
US11014969B2 (en) 2021-05-25
WO2014210018A1 (en) 2014-12-31
JP2019187441A (ja) 2019-10-31

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