ES290157A1 - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- ES290157A1 ES290157A1 ES0290157A ES290157A ES290157A1 ES 290157 A1 ES290157 A1 ES 290157A1 ES 0290157 A ES0290157 A ES 0290157A ES 290157 A ES290157 A ES 290157A ES 290157 A1 ES290157 A1 ES 290157A1
- Authority
- ES
- Spain
- Prior art keywords
- branched
- carbon atoms
- aliphatic hydrocarbon
- hydrocarbon group
- chain aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:1005893/C2/1> wherein A is a divalent straight- or branched-chain aliphatic hydrocarbon group having 2 to 6 carbon atoms, B is a single bond or a group -A1-NH, wherein the nitrogen atom is attached to the quinoline nucleus and A1 is a divalent straight or branched-chain aliphatic hydrocarbon group having 2 to 6 carbon atoms, non-toxic acid addition salts thereof, and their preparation by oxidation of the corresponding piperazine derivatives. The compounds of the invention have anti-malarial activity and may be used in pharmaceutical compositions in combination with a carrier, for example in forms suitable for oral, parenteral or rectal administration, such as tablets, pills, powders, granules, capsules, emulsions, solutions, suspensions, syrups, elixirs or suppositories. Specifications 973,903, 986,350 and 1,002,187 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR906819A FR1405217A (en) | 1962-08-13 | 1962-08-13 | New quinoline derivatives and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES290157A1 true ES290157A1 (en) | 1963-12-16 |
Family
ID=8785091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0290157A Expired ES290157A1 (en) | 1962-08-13 | 1963-07-20 | Quinoline derivatives |
Country Status (9)
Country | Link |
---|---|
AT (1) | AT242142B (en) |
BE (1) | BE636091A (en) |
CH (1) | CH412909A (en) |
DK (1) | DK103187C (en) |
ES (1) | ES290157A1 (en) |
FR (2) | FR1405217A (en) |
GB (1) | GB1005893A (en) |
LU (1) | LU43902A1 (en) |
NL (1) | NL296359A (en) |
-
1962
- 1962-08-13 FR FR906819A patent/FR1405217A/en not_active Expired
- 1962-10-29 FR FR913756A patent/FR2371M/fr not_active Expired
-
1963
- 1963-06-14 LU LU43902A patent/LU43902A1/en unknown
- 1963-07-11 CH CH865563A patent/CH412909A/en unknown
- 1963-07-20 ES ES0290157A patent/ES290157A1/en not_active Expired
- 1963-07-31 AT AT615363A patent/AT242142B/en active
- 1963-08-07 NL NL296359A patent/NL296359A/en unknown
- 1963-08-08 GB GB31388/63A patent/GB1005893A/en not_active Expired
- 1963-08-09 DK DK382363AA patent/DK103187C/en active
- 1963-08-12 BE BE636091A patent/BE636091A/en unknown
Also Published As
Publication number | Publication date |
---|---|
LU43902A1 (en) | 1963-08-14 |
NL296359A (en) | 1965-05-10 |
FR1405217A (en) | 1965-07-09 |
CH412909A (en) | 1966-05-15 |
DK103187C (en) | 1965-11-29 |
GB1005893A (en) | 1965-09-29 |
FR2371M (en) | 1964-04-03 |
AT242142B (en) | 1965-08-25 |
BE636091A (en) | 1964-02-12 |
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