ES2900612T3 - Péptido ligasa y su uso - Google Patents

Péptido ligasa y su uso Download PDF

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Publication number
ES2900612T3
ES2900612T3 ES18719246T ES18719246T ES2900612T3 ES 2900612 T3 ES2900612 T3 ES 2900612T3 ES 18719246 T ES18719246 T ES 18719246T ES 18719246 T ES18719246 T ES 18719246T ES 2900612 T3 ES2900612 T3 ES 2900612T3
Authority
ES
Spain
Prior art keywords
peptide
seq
amino acid
polypeptide
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18719246T
Other languages
English (en)
Spanish (es)
Inventor
Mark Howarth
Can M Buldun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Application granted granted Critical
Publication of ES2900612T3 publication Critical patent/ES2900612T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES18719246T 2017-04-10 2018-04-10 Péptido ligasa y su uso Active ES2900612T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1705750.6A GB201705750D0 (en) 2017-04-10 2017-04-10 Peptide ligase and use therof
PCT/GB2018/050943 WO2018189517A1 (en) 2017-04-10 2018-04-10 Peptide ligase and use thereof

Publications (1)

Publication Number Publication Date
ES2900612T3 true ES2900612T3 (es) 2022-03-17

Family

ID=58744859

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18719246T Active ES2900612T3 (es) 2017-04-10 2018-04-10 Péptido ligasa y su uso

Country Status (12)

Country Link
US (1) US10889622B2 (enExample)
EP (1) EP3610005B1 (enExample)
JP (1) JP7075678B2 (enExample)
KR (1) KR102669378B1 (enExample)
CN (2) CN118389457A (enExample)
AU (1) AU2018251237B2 (enExample)
BR (1) BR112019021009A2 (enExample)
CA (1) CA3059132A1 (enExample)
DK (1) DK3610005T3 (enExample)
ES (1) ES2900612T3 (enExample)
GB (1) GB201705750D0 (enExample)
WO (1) WO2018189517A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111954683A (zh) 2018-04-05 2020-11-17 生物辐射Abd瑟罗泰克有限公司 感兴趣的蛋白质的展示系统
IL278418B2 (en) 2018-05-04 2024-01-01 Spybiotech Ltd Vaccine composition
GB201819850D0 (en) 2018-12-05 2019-01-23 Univ Oxford Innovation Ltd Polypeptide and its use in affinity purification
GB201903479D0 (en) 2019-03-14 2019-05-01 Univ Oxford Innovation Ltd Polypeptide with enchanced rate of spontaneous isopeptide bond formation with it's peptide tag partner and uses thereof
WO2020188350A1 (en) 2019-03-18 2020-09-24 Bio-Rad Abd Serotec Gmbh Protection of spytag-containing periplasmic fusion proteins from protease tsp and ompt degradation
GB201915905D0 (en) 2019-11-01 2019-12-18 Spybiotech Ltd Viruses with modified capsid proteins
US12298314B2 (en) 2020-10-09 2025-05-13 10X Genomics, Inc. Methods and compositions for analyzing target binding of molecules
WO2022076914A1 (en) 2020-10-09 2022-04-14 10X Genomics, Inc. Methods and compositions for profiling immune repertoire
GB202019817D0 (en) 2020-12-15 2021-01-27 Univ Oxford Innovation Ltd Ligand-binding polypeptides and uses thereof
CN112877347B (zh) * 2021-01-28 2023-02-17 华南理工大学 一种多酶复合体及其构建方法和应用
GB202104104D0 (en) 2021-03-24 2021-05-05 Liliumx Ltd Platform and method
GB202104999D0 (en) 2021-04-08 2021-05-26 Univ Oxford Innovation Ltd Polypeptides that interact with peptide tags at loops or termini and uses thereof
GB202106361D0 (en) 2021-05-04 2021-06-16 Spybiotech Ltd Viral vectored vaccines
US20240240203A1 (en) 2021-05-04 2024-07-18 SpyBiotech Limited Adenoviral vectors and vaccines thereof
GB202117283D0 (en) 2021-11-30 2022-01-12 Univ Oxford Innovation Ltd Switchable polypeptide and its use for gentle affinity purification
US12043862B2 (en) 2021-12-28 2024-07-23 Encodia, Inc. High-throughput serotyping and antibody profiling assays
CN120659804A (zh) 2022-09-28 2025-09-16 维连克治疗有限公司 多价蛋白质及筛选方法
GB202306808D0 (en) 2023-05-09 2023-06-21 Univ Oxford Innovation Ltd Method for detecting interactions
GB202313175D0 (en) 2023-08-30 2023-10-11 Univ Oxford Innovation Ltd A bivalent polypeptide scaffold and uses thereof
US20250122482A1 (en) 2023-09-07 2025-04-17 Regeneron Pharmaceuticals, Inc. Production and purification of covalently surface modified adeno-associated virus
WO2025083285A1 (en) 2023-10-20 2025-04-24 Norwegian University Of Science And Technology (Ntnu) Methods and products for use in genome-wide chromatin profiling
WO2025111473A1 (en) 2023-11-21 2025-05-30 Regeneron Pharmaceuticals, Inc. Covalently surface modified adeno-associated virus production by in vitro conjugation, and purification of covalently surface modified adeno-associated virus
GB202317925D0 (en) 2023-11-23 2024-01-10 Spybiotech Ltd Vaccines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE414775T1 (de) * 1997-05-16 2008-12-15 Novozymes Inc Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
EP2385842A1 (en) 2009-01-12 2011-11-16 Novartis AG Cna_b domain antigens in vaccines against gram positive bacteria
GB201002362D0 (en) 2010-02-11 2010-03-31 Isis Innovation Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds
WO2013124473A1 (en) * 2012-02-24 2013-08-29 Novartis Ag Pilus proteins and compositions
MX2016015572A (es) * 2014-06-03 2017-02-27 Dsm Ip Assets Bv Endoproteasa especifica para prolina y usos de la misma.
MX376332B (es) * 2014-06-03 2025-03-07 Dsm Ip Assets Bv Endoproteasa especifica para prolina y usos de la misma.
DE16703049T1 (de) 2015-01-15 2018-07-12 University Of Copenhagen Virusähnliche partikel mit effizienter epitopanzeige
GB201509782D0 (en) * 2015-06-05 2015-07-22 Isis Innovation Methods and products for fusion protein synthesis

Also Published As

Publication number Publication date
CN118389457A (zh) 2024-07-26
US20200115422A1 (en) 2020-04-16
KR102669378B1 (ko) 2024-05-24
WO2018189517A1 (en) 2018-10-18
EP3610005A1 (en) 2020-02-19
AU2018251237A1 (en) 2019-10-24
CN110582566A (zh) 2019-12-17
DK3610005T3 (da) 2021-12-13
AU2018251237B2 (en) 2024-01-18
BR112019021009A2 (pt) 2020-05-05
US10889622B2 (en) 2021-01-12
KR20190137820A (ko) 2019-12-11
EP3610005B1 (en) 2021-09-29
CA3059132A1 (en) 2018-10-18
JP2020516314A (ja) 2020-06-11
GB201705750D0 (en) 2017-05-24
CN110582566B (zh) 2024-05-10
JP7075678B2 (ja) 2022-05-26

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