ES2875742T3 - Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman - Google Patents

Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman Download PDF

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Publication number
ES2875742T3
ES2875742T3 ES18169211T ES18169211T ES2875742T3 ES 2875742 T3 ES2875742 T3 ES 2875742T3 ES 18169211 T ES18169211 T ES 18169211T ES 18169211 T ES18169211 T ES 18169211T ES 2875742 T3 ES2875742 T3 ES 2875742T3
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Spain
Prior art keywords
composition
drug
thip
use according
pharmaceutically acceptable
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ES18169211T
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English (en)
Spanish (es)
Inventor
Matthew During
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Ovid Therapeutics Inc
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Ovid Therapeutics Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
ES18169211T 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman Active ES2875742T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462008939P 2014-06-06 2014-06-06

Publications (1)

Publication Number Publication Date
ES2875742T3 true ES2875742T3 (es) 2021-11-11

Family

ID=54767324

Family Applications (2)

Application Number Title Priority Date Filing Date
ES18169211T Active ES2875742T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman
ES15803364T Active ES2876350T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15803364T Active ES2876350T3 (es) 2014-06-06 2015-06-03 Métodos para aumentar la inhibición tónica y tratamiento del insomnio secundario

Country Status (20)

Country Link
US (11) US20150352085A1 (https=)
EP (3) EP3151832B1 (https=)
JP (4) JP2017516868A (https=)
AR (1) AR100772A1 (https=)
AU (4) AU2015269667B2 (https=)
CA (1) CA2950845C (https=)
CY (2) CY1124368T1 (https=)
DK (2) DK3151832T3 (https=)
ES (2) ES2875742T3 (https=)
HR (2) HRP20210901T1 (https=)
HU (2) HUE055155T2 (https=)
IL (2) IL249287B (https=)
LT (2) LT3372229T (https=)
MX (2) MX380868B (https=)
PL (2) PL3372229T3 (https=)
PT (2) PT3151832T (https=)
RS (2) RS62006B1 (https=)
SI (2) SI3372229T1 (https=)
SM (2) SMT202100343T1 (https=)
WO (1) WO2015187851A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3065782B8 (en) 2013-11-05 2021-05-26 Elena Molokanova Nanostructure conjugates for modulation of location-specific subtypes of receptors and ion channels
DK3151832T3 (da) 2014-06-06 2021-06-14 Ovid Therapeutics Inc Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed
US10434308B2 (en) 2015-05-29 2019-10-08 Medtronic, Inc. Impedance matching and electrode conditioning in patient interface systems
US10080898B2 (en) * 2015-05-29 2018-09-25 Medtronic, Inc. Simultaneous physiological sensing and stimulation with saturation detection
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
IL256912B2 (en) * 2015-07-17 2024-01-01 Ovid Therapeutics Inc Methods of treating developmental disorders with gaboxadol
WO2018017639A1 (en) * 2016-07-19 2018-01-25 Georgia State University Research Foundation Methods for treating rett syndrome
EP4233861A3 (en) 2016-08-11 2023-10-11 Ovid Therapeutics, Inc. Compositions for treatment of essential tremor
EP3528807A4 (en) * 2016-11-22 2020-06-17 Ovid Therapeutics Inc METHOD FOR TREATING DEVELOPMENT DISORDERS AND / OR FALLS WITH FLUPIRTIN
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
JP2020529440A (ja) 2017-08-04 2020-10-08 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. 糖尿病および関連する状態の処置におけるガボキサドールの使用
US11181384B2 (en) * 2018-07-23 2021-11-23 Waymo Llc Verifying map data using challenge questions
MX2021003302A (es) 2018-09-20 2021-05-13 Ovid Therapeutics Inc Uso de gaboxadol para el tratamiento del sindrome de tourette, los tics y la tartamudez.
US11123332B2 (en) * 2018-11-21 2021-09-21 Certego Therapeutics Inc. Gaboxadol for reducing risk of suicide and rapid relief of depression
EP3880201A4 (en) 2018-12-17 2022-07-27 Ovid Therapeutics Inc. USE OF GABOXADOL IN THE TREATMENT OF NON-24 HOUR SLEEP waking disorder
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
KR20220035195A (ko) * 2019-07-15 2022-03-21 오비드 테라퓨틱스 인크. 치료적 치료를 위한 가복사돌을 포함하는 약학적 제제
EP4051272A4 (en) 2019-12-18 2023-01-04 Ovid Therapeutics Inc. GABOXADOL FOR THE THERAPEUTIC TREATMENT OF 1P36 DELETION SYNDROME
MX2022014599A (es) 2020-05-20 2022-12-16 Certego Therapeutics Inc Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos.
JP7600661B2 (ja) * 2020-12-11 2024-12-17 artience株式会社 貼付剤
US20240285562A1 (en) * 2023-02-17 2024-08-29 Ovid Therapeutics Inc. Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid in the treatment of multiple sclerosis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK270278A (da) 1977-06-20 1978-12-21 Krogsgaard Larsen P Cycliske aminosyrer
US4362731A (en) 1980-09-01 1982-12-07 Sandoz Ltd. Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4353910A (en) 1981-11-27 1982-10-12 Kefalas A/S Derivatives of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridine-3-one, pharmaceutical compositions and methods of treatment
DE19525598C2 (de) 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
DE19526864A1 (de) 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US6461644B1 (en) 1996-03-25 2002-10-08 Richard R. Jackson Anesthetizing plastics, drug delivery plastics, and related medical products, systems and methods
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
US6676961B1 (en) 2002-03-06 2004-01-13 Automated Carrier Technologies, Inc. Transdermal patch assembly
US20050137222A1 (en) * 2003-12-18 2005-06-23 H. Lundbeck A/S Treatment of insomnia in human patients
JP2007530604A (ja) 2004-04-02 2007-11-01 ハー・ルンドベック・アクチエゼルスカベット 呼吸機能障害の治療
DE102005020882A1 (de) * 2005-05-04 2006-11-09 Dömling, Alexander, Dr. Verwendung von Gaboxadol und Derivaten zur Behandlung von Kinase-induzierten Krankheiten
US20110046090A1 (en) * 2005-10-31 2011-02-24 Braincells Inc. Modulation of neurogenesis with gaba agents and gaba analogs
US20090143335A1 (en) 2007-10-29 2009-06-04 H. Lundbeck A/S Modified absorption formulation of gaboxadol
CA2705733C (en) 2007-11-13 2015-02-03 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
CN102137667A (zh) * 2008-09-01 2011-07-27 H.隆德贝克有限公司 包含加波沙朵和patl或oat抑制剂的药物组合物
DK3151832T3 (da) 2014-06-06 2021-06-14 Ovid Therapeutics Inc Fremgangsmåder til øgning af tonisk hæmning og behandling af sekundær søvnløshed
IL256912B2 (en) * 2015-07-17 2024-01-01 Ovid Therapeutics Inc Methods of treating developmental disorders with gaboxadol
US9399034B1 (en) 2015-08-11 2016-07-26 Ovid Therapeutics Inc Methods of sedation during critical care treatment

Also Published As

Publication number Publication date
RS62007B1 (sr) 2021-07-30
DK3151832T3 (da) 2021-06-14
EP3151832A1 (en) 2017-04-12
JP2023123442A (ja) 2023-09-05
HUE055155T2 (hu) 2021-11-29
MX391502B (es) 2025-03-21
SMT202100340T1 (it) 2021-07-12
US20150352085A1 (en) 2015-12-10
US9744159B2 (en) 2017-08-29
JP2021178836A (ja) 2021-11-18
PL3372229T3 (pl) 2021-10-04
AU2020217342A1 (en) 2020-08-27
PT3151832T (pt) 2021-06-15
US20160038469A1 (en) 2016-02-11
US20160228418A1 (en) 2016-08-11
CY1124368T1 (el) 2022-07-22
US20170273956A1 (en) 2017-09-28
HRP20210901T1 (hr) 2021-09-17
RS62006B1 (sr) 2021-07-30
JP2017516868A (ja) 2017-06-22
US11278529B2 (en) 2022-03-22
CA2950845C (en) 2023-04-25
US9446028B2 (en) 2016-09-20
IL268960B (en) 2021-05-31
US20170087133A1 (en) 2017-03-30
EP3372229B1 (en) 2021-03-24
AU2022200085A1 (en) 2022-02-03
MX380868B (es) 2025-03-12
AU2024202604A1 (en) 2024-05-09
EP3372229A1 (en) 2018-09-12
DK3372229T3 (da) 2021-06-14
HRP20210902T1 (hr) 2021-09-17
SI3151832T1 (sl) 2021-08-31
CY1124366T1 (el) 2022-07-22
US20180303805A1 (en) 2018-10-25
SI3372229T1 (sl) 2021-09-30
IL268960A (en) 2019-10-31
PT3372229T (pt) 2021-06-17
AU2015269667A1 (en) 2016-12-22
MX2016016136A (es) 2017-07-05
WO2015187851A1 (en) 2015-12-10
IL249287A0 (en) 2017-02-28
US9801864B2 (en) 2017-10-31
LT3151832T (lt) 2021-07-12
EP3795156A1 (en) 2021-03-24
US20220016091A1 (en) 2022-01-20
US20250025448A1 (en) 2025-01-23
IL249287B (en) 2021-03-25
AU2020217342B2 (en) 2021-10-07
SMT202100343T1 (it) 2021-07-12
US20230051859A1 (en) 2023-02-16
US20170071917A1 (en) 2017-03-16
JP2020063264A (ja) 2020-04-23
MX2020012404A (es) 2022-04-11
ES2876350T3 (es) 2021-11-12
CA2950845A1 (en) 2015-12-10
AU2015269667B2 (en) 2020-07-30
US9339495B2 (en) 2016-05-17
PL3151832T3 (pl) 2021-10-25
HUE055400T2 (hu) 2021-11-29
EP3151832A4 (en) 2018-01-17
LT3372229T (lt) 2021-07-12
US20180015076A1 (en) 2018-01-18
AR100772A1 (es) 2016-11-02
EP3151832B1 (en) 2021-03-24

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