ES2813437T3 - Métodos para mejorar la eficiencia de la transducción vectorial en linfocitos T - Google Patents
Métodos para mejorar la eficiencia de la transducción vectorial en linfocitos T Download PDFInfo
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- ES2813437T3 ES2813437T3 ES15818898T ES15818898T ES2813437T3 ES 2813437 T3 ES2813437 T3 ES 2813437T3 ES 15818898 T ES15818898 T ES 15818898T ES 15818898 T ES15818898 T ES 15818898T ES 2813437 T3 ES2813437 T3 ES 2813437T3
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| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| EP2971279B1 (en) | 2013-03-15 | 2019-11-13 | The Trustees of Princeton University | Methods and devices for high throughput purification |
| JP6754761B2 (ja) * | 2014-07-11 | 2020-09-16 | セルジーン コーポレイション | Ｔリンパ球へのベクター導入効率の改善方法 |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| US10844353B2 (en) | 2017-09-01 | 2020-11-24 | Gpb Scientific, Inc. | Methods for preparing therapeutically active cells using microfluidics |
| DE102018010282A1 (de) | 2018-01-17 | 2019-07-18 | Immatics US, Inc. | Verfahren zur Feststellung der Wirksamkeit von viralen Vektoren |
| DE102018100967B4 (de) | 2018-01-17 | 2019-08-14 | Immatics US, Inc. | Verfahren zur feststellung der wirksamkeit von viralen vektoren |
| CN108715865B (zh) * | 2018-05-28 | 2021-09-21 | 福建师范大学 | 用于提高细胞转染效率的试剂组合物 |
| EP3999081A1 (en) | 2019-07-18 | 2022-05-25 | GPB Scientific, Inc. | Ordered processing of blood products to produce therapeutically active cells |
| JP2023508465A (ja) | 2019-12-28 | 2023-03-02 | ジーピービー・サイエンティフィック・インコーポレイテッド | 粒子および細胞を処理するためのマイクロ流体カートリッジ |
| KR20230167384A (ko) * | 2021-04-06 | 2023-12-08 | 유니세트 바이오테크 씨오. 엘엘씨 | γδ T 세포의 바이러스 형질 도입의 안정성을 개선하기 위한 방법 및 이의 응용 |
| WO2023286088A1 (en) * | 2021-07-16 | 2023-01-19 | Indian Institute Of Science Education And Research Bhopal | Methods and compositions for viral vector transduction |
| WO2025180499A1 (zh) * | 2024-02-28 | 2025-09-04 | 南京因领生物科技有限公司 | 一种提高细胞中病毒包装产量或质量的方法 |
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| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US5665577A (en) | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
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| EP0824594B1 (en) * | 1995-05-04 | 2005-04-06 | The United States of America as Representend by The Secretary of the Navy | Improved methods for transfecting t cells |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| ATE528406T1 (de) | 1999-04-29 | 2011-10-15 | Gbp Ip Llc | Verfahren und mittel zur herstellung von sicheren,rekombinanten lentivirusvektoren mit hohem titer |
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| ATE488252T1 (de) * | 2003-05-05 | 2010-12-15 | Virxsys Corp | Erhöhte transduktion mit abc- transportersubstratenhemmern |
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| WO2006089001A2 (en) * | 2005-02-16 | 2006-08-24 | Lentigen Corporation | Lentiviral vectors and their use |
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| PT2471907T (pt) | 2005-12-29 | 2019-01-28 | Celularity Inc | Populações de células estaminais placentárias |
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| JP5869342B2 (ja) | 2008-11-19 | 2016-02-24 | アンスロジェネシス コーポレーション | 羊膜由来接着細胞 |
| EP3358007A1 (en) | 2010-07-13 | 2018-08-08 | Celularity, Inc. | Methods of generating natural killer cells |
| WO2012072096A1 (en) * | 2010-12-03 | 2012-06-07 | Biontech Ag | Method for cellular rna expression |
| DK3763820T3 (da) * | 2012-02-29 | 2022-02-07 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh | Retroviral transduktion ved hjælp af poloxamerer |
| EP2836239A1 (en) * | 2012-04-11 | 2015-02-18 | The United States of America, as Represented By the Secretary, Department of Health and Human Services | Chimeric antigen receptors targeting b-cell maturation antigen |
| WO2014046617A1 (en) * | 2012-09-19 | 2014-03-27 | Agency For Science, Technology And Research | Compositions and methods for treating cancer |
| JP6754761B2 (ja) * | 2014-07-11 | 2020-09-16 | セルジーン コーポレイション | Ｔリンパ球へのベクター導入効率の改善方法 |
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