ES280885A1 - Procedure for obtaining benzolsulfonil-semicarbacides (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Procedure for obtaining benzolsulfonyl-semicarbacidos of the general formula **FIGURE** - where X represents an alkyl residue containing from 2 to 6 carbon atoms and -Z-Z'' - represents an alkylene chain containing 5 carbon atoms, which may eventually be replaced by other low-weight alkyl residues molecular - as well as its salts, characterized by reacting correspondingly substituted benzolsulfonyl isocyanates with N, N-alkylene-hydrazines, or, in reverse reaction, benzolsulfonamides correspondingly substituted with N, N-alkyleneimine isocyanates, and can also be used instead of the mentioned isocyanates, in general, also those compounds that in the course of the reaction form such isocyanates or that react as such isocyanates; or reacting correspondingly substituted benzolsulfonyl-carbamic acid esters and, respectively, correspondingly substituted benzolsulfonyl-thiocarbamic acid esters, containing a low molecular weight alkyl residue or an aryl residue in the steric component, with N-N'-alkylene- hydrazines, or, conversely, esters of N, N-alkylene-hydrazino-N'-carbonic acid having in the steric component a low molecular weight alkyl residue or an aryl residue, and respectively corresponding hydrazino acid esters -monothio-carbonic with benzolsulfonamides; or by reacting with correspondingly substituted N, N-alkylene hydrazines, correspondingly substituted benzolsulfonylcarbamic acid halides and, respectively, N, N-alkylene-N'-carbonic acid halides with correspondingly substituted benzolsulfonamides; or by being transformed, with N-N-alkylene hydrazines, benzolsulfonyl-ureas without substituents on the side of the urea molecule separated from the sulfonyl group or that are substituted once or twice by low molecular weight alkyl residues or aryl residues; or by being transformed with suitable N, N-alkylene-hydrazines corresponding N-benzolsulfonyl-N'-acyl-ureas and respectively also bis- (benzolsulfonyl) -ureas; or by being transformed with corresponding substituted benzolsulfonamides N1, N1-alkylene-semicarbacidos that may optionally be substituted in the nitrogen atom 4 by an aromatic acid residue, or by a NO2 group or by corresponding 1-benzolsulfonyl-3-alkyleneimino- acids being hydrolyzed. parabolic; or by removing in a current way, of corresponding benzolsulfonyl-thiosemicarbacidos, the sulfur; and transform, with physiologically tolerable bases or acids, in the corresponding rooms, the products thus obtained. (Machine-translation by Google Translate, not legally binding)