ES2777228T3 - Métodos para evaluar la deficiencia de recombinación homóloga y predecir la respuesta al tratamiento del cáncer - Google Patents
Métodos para evaluar la deficiencia de recombinación homóloga y predecir la respuesta al tratamiento del cáncer Download PDFInfo
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| WO2016185406A1 (en) | 2015-05-19 | 2016-11-24 | Nadathur Estates Pvt. Ltd. | Method for identification of a deficient brca1 function |
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| WO2017165270A1 (en) * | 2016-03-21 | 2017-09-28 | Myriad Genetics, Inc. | Homologous recombination deficiency to predict neoadjuvant chemotherapy necessity in bladder cancer |
| WO2017178509A1 (en) | 2016-04-12 | 2017-10-19 | Xentech | Methods for predicting sensibility to treatment with parp inhibitors in cancerous patients |
| JP7224185B2 (ja) * | 2016-05-01 | 2023-02-17 | ゲノム・リサーチ・リミテッド | Ｄｎａサンプルを特徴付ける方法 |
| GB2555765A (en) | 2016-05-01 | 2018-05-16 | Genome Res Ltd | Method of detecting a mutational signature in a sample |
| EP3452937B1 (en) | 2016-05-01 | 2025-10-22 | Genome Research Limited | Method of characterising a dna sample |
| SG11201811564QA (en) | 2016-06-29 | 2019-01-30 | Tesaro Inc | Methods of treating ovarian cancer |
| BR112020024727A2 (pt) | 2018-06-11 | 2021-03-23 | Foundation Medicine, Inc. | composições e métodos para avaliação de alterações genômicas |
| JPWO2020137076A1 (ja) * | 2018-12-28 | 2021-11-11 | 国立大学法人 東京大学 | Ｐａｒｐ阻害剤に対する癌の感受性の予測方法および相同組換修復不全を有する癌の検出方法 |
| US10975445B2 (en) | 2019-02-12 | 2021-04-13 | Tempus Labs, Inc. | Integrated machine-learning framework to estimate homologous recombination deficiency |
| ES2989374T3 (es) | 2019-12-10 | 2024-11-26 | Tempus Ai Inc | Sistemas y procedimientos para predecir el estado de deficiencia de recombinación homóloga de una muestra |
| WO2021122620A1 (en) * | 2019-12-16 | 2021-06-24 | Agilent Technologies, Inc. | Genomic scarring assays and related methods |
| EP3945525A1 (en) | 2020-07-27 | 2022-02-02 | Sophia Genetics S.A. | Methods for identifying chromosomal spatial instability such as homologous repair deficiency in low coverage next-generation sequencing data |
| CN111883211B (zh) * | 2020-08-07 | 2021-04-23 | 张哲� | 一种表征hrd同源重组修复缺陷的基因瘢痕及鉴定方法 |
| US11718869B2 (en) * | 2020-08-12 | 2023-08-08 | Zhenyue Biotechnology Jiangsu Co., Ltd. | Method and kit for determining genome instability based on next generation sequencing (NGS) |
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| JP7585015B2 (ja) | 2020-12-04 | 2024-11-18 | 株式会社東芝 | 核酸構築物のセット、キット、検出方法及び薬剤効果予測方法 |
| US20240026462A1 (en) * | 2021-01-10 | 2024-01-25 | Ying Ja CHEN | Homologous recombination deficiency determining method and kit thereof |
| BE1029144B1 (fr) | 2021-02-25 | 2022-09-20 | Oncodna | Méthode de caracterisation d'une tumeur à l'aide d'un séquençage ciblé |
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