ES2768900T3 - Combinaciones de agentes terapéuticos contra cáncer - Google Patents
Combinaciones de agentes terapéuticos contra cáncer Download PDFInfo
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- ES2768900T3 ES2768900T3 ES15710714T ES15710714T ES2768900T3 ES 2768900 T3 ES2768900 T3 ES 2768900T3 ES 15710714 T ES15710714 T ES 15710714T ES 15710714 T ES15710714 T ES 15710714T ES 2768900 T3 ES2768900 T3 ES 2768900T3
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- compound
- physiologically acceptable
- acceptable salts
- azetidin
- ethylamino
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- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
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- 206010046766 uterine cancer Diseases 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461974765P | 2014-04-03 | 2014-04-03 | |
| PCT/EP2015/000525 WO2015149909A1 (en) | 2014-04-03 | 2015-03-09 | Combinations of cancer therapeutics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2768900T3 true ES2768900T3 (es) | 2020-06-24 |
Family
ID=52692591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15710714T Active ES2768900T3 (es) | 2014-04-03 | 2015-03-09 | Combinaciones de agentes terapéuticos contra cáncer |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9980966B2 (OSRAM) |
| EP (1) | EP3125935B1 (OSRAM) |
| JP (1) | JP6629753B2 (OSRAM) |
| KR (1) | KR102410696B1 (OSRAM) |
| CN (1) | CN106456752B (OSRAM) |
| AR (1) | AR099931A1 (OSRAM) |
| AU (1) | AU2015240094B2 (OSRAM) |
| CA (1) | CA2944573C (OSRAM) |
| ES (1) | ES2768900T3 (OSRAM) |
| IL (1) | IL248126A0 (OSRAM) |
| MX (1) | MX370540B (OSRAM) |
| NZ (1) | NZ725361A (OSRAM) |
| RU (1) | RU2733401C2 (OSRAM) |
| SG (1) | SG11201608189WA (OSRAM) |
| WO (1) | WO2015149909A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2022101459A1 (en) * | 2020-11-16 | 2022-05-19 | Merck Patent Gmbh | Kinase inhibitor combinations for cancer treatment |
| WO2025168601A1 (en) * | 2024-02-05 | 2025-08-14 | Evexta Bio | Quinazoline carboxamide azetidine compounds for use in treating hormone dependent diseases |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TW200306819A (en) | 2002-01-25 | 2003-12-01 | Vertex Pharma | Indazole compounds useful as protein kinase inhibitors |
| JP2006522124A (ja) | 2003-04-03 | 2006-09-28 | バーテックス ファーマシューティカルズ インコーポレイテッド | プロテインキナーゼのインヒビターとして有用な組成物 |
| EP1670771A4 (en) | 2003-09-30 | 2010-09-01 | Irm Llc | COMPOUNDS AND COMPOSITIONS INHIBITING PROTEIN-KINASES |
| WO2005039506A2 (en) | 2003-10-24 | 2005-05-06 | Exelixis, Inc. | P70s6 kinase modulators and method of use |
| BRPI0416801A (pt) | 2003-11-21 | 2007-01-09 | Novartis Ag | derivados de 1h-imidazoquinolina como inibidores de proteìna sinase |
| KR20060123463A (ko) | 2003-12-09 | 2006-12-01 | 더 거번먼트 오브 더 유나이티드 스테이츠 오브 어메리카 애즈 레프리젠티드 바이 더 세크러터리 오브 더 디파트먼트 오브 헬쓰 앤드 휴먼 써비시즈 | 면역 반응을 억제하거나 증식성 장애를 치료하는 방법들 |
| US8076338B2 (en) | 2004-04-23 | 2011-12-13 | Exelixis, Inc. | Kinase modulators and methods of use |
| JP5274842B2 (ja) | 2004-12-28 | 2013-08-28 | エグゼリクシス， インコーポレイテッド | 免疫疾患、炎症疾患および増殖疾患の処置のためのセリン−スレオニンキナーゼモジュレーター（ｐ７０Ｓ６Ｋ、Ａｋｔ−１およびＡｋｔ−２）としての［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジンまたは［１Ｈ−ピペラゾ［３，４−ｄ］ピリミジン−４−イル］−ピペラジン化合物 |
| GB0501999D0 (en) | 2005-02-01 | 2005-03-09 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| US20060188498A1 (en) * | 2005-02-18 | 2006-08-24 | Genentech, Inc. | Methods of using death receptor agonists and EGFR inhibitors |
| US8343953B2 (en) | 2005-06-22 | 2013-01-01 | Astex Therapeutics Limited | Pharmaceutical compounds |
| CN101300029A (zh) * | 2005-11-04 | 2008-11-05 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| UA99284C2 (ru) | 2007-05-11 | 2012-08-10 | Елі Ліллі Енд Компані | ИНГИБИТОРЫ р70 S6-КИНАЗЫ |
| UY31800A (es) | 2008-05-05 | 2009-11-10 | Smithkline Beckman Corp | Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb |
| EP2396307B1 (en) | 2009-02-11 | 2014-10-15 | Merck Patent GmbH | Novel amino azaheterocyclic carboxamides |
| EP2571901B1 (en) | 2010-05-20 | 2019-01-02 | Ablynx N.V. | Biological materials related to her3 |
| UA110113C2 (xx) | 2010-07-29 | 2015-11-25 | Біциклічні азагетероциклічні карбоксаміди | |
| SI2643313T1 (sl) * | 2010-11-24 | 2016-11-30 | Merck Patent Gmbh | Kinazolin-karboksamidni azetidini |
| AU2014228385B2 (en) * | 2013-03-11 | 2018-08-09 | Merck Patent Gmbh | 6-[4-(1-H-imidazol-2-yl]piperidin-1 -yl]pyrimidin-4-amine derivatives as modulators of kinase activity |
-
2015
- 2015-03-09 KR KR1020167030676A patent/KR102410696B1/ko active Active
- 2015-03-09 NZ NZ725361A patent/NZ725361A/en unknown
- 2015-03-09 MX MX2016012825A patent/MX370540B/es active IP Right Grant
- 2015-03-09 CN CN201580018245.XA patent/CN106456752B/zh active Active
- 2015-03-09 US US15/128,045 patent/US9980966B2/en active Active
- 2015-03-09 CA CA2944573A patent/CA2944573C/en active Active
- 2015-03-09 WO PCT/EP2015/000525 patent/WO2015149909A1/en not_active Ceased
- 2015-03-09 EP EP15710714.5A patent/EP3125935B1/en active Active
- 2015-03-09 ES ES15710714T patent/ES2768900T3/es active Active
- 2015-03-09 SG SG11201608189WA patent/SG11201608189WA/en unknown
- 2015-03-09 RU RU2016143153A patent/RU2733401C2/ru active
- 2015-03-09 AU AU2015240094A patent/AU2015240094B2/en active Active
- 2015-03-09 JP JP2016560799A patent/JP6629753B2/ja active Active
- 2015-04-01 AR ARP150100982A patent/AR099931A1/es unknown
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2016
- 2016-09-29 IL IL248126A patent/IL248126A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015240094A1 (en) | 2016-11-17 |
| EP3125935A1 (en) | 2017-02-08 |
| SG11201608189WA (en) | 2016-10-28 |
| NZ725361A (en) | 2022-09-30 |
| BR112016020135A2 (pt) | 2017-08-15 |
| US20170100402A1 (en) | 2017-04-13 |
| AR099931A1 (es) | 2016-08-31 |
| KR20160133005A (ko) | 2016-11-21 |
| IL248126A0 (en) | 2016-11-30 |
| JP2017509683A (ja) | 2017-04-06 |
| CA2944573A1 (en) | 2015-10-08 |
| EP3125935B1 (en) | 2019-10-23 |
| US9980966B2 (en) | 2018-05-29 |
| CN106456752A (zh) | 2017-02-22 |
| MX370540B (es) | 2019-12-17 |
| KR102410696B1 (ko) | 2022-06-17 |
| RU2016143153A (ru) | 2018-05-04 |
| CA2944573C (en) | 2022-10-25 |
| RU2016143153A3 (OSRAM) | 2018-10-17 |
| JP6629753B2 (ja) | 2020-01-15 |
| WO2015149909A1 (en) | 2015-10-08 |
| MX2016012825A (es) | 2017-01-05 |
| RU2733401C2 (ru) | 2020-10-01 |
| CN106456752B (zh) | 2020-11-20 |
| AU2015240094B2 (en) | 2020-07-30 |
| BR112016020135A8 (pt) | 2021-07-06 |
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