ES2768264T3 - Nuevos péptidos D-enantioméricos derivados de D3 y su uso - Google Patents
Nuevos péptidos D-enantioméricos derivados de D3 y su uso Download PDFInfo
- Publication number
- ES2768264T3 ES2768264T3 ES13776426T ES13776426T ES2768264T3 ES 2768264 T3 ES2768264 T3 ES 2768264T3 ES 13776426 T ES13776426 T ES 13776426T ES 13776426 T ES13776426 T ES 13776426T ES 2768264 T3 ES2768264 T3 ES 2768264T3
- Authority
- ES
- Spain
- Prior art keywords
- seq
- peptides
- peptide
- oligomers
- peptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102012108598.6A DE102012108598A1 (de) | 2012-09-14 | 2012-09-14 | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| PCT/EP2013/068992 WO2014041115A2 (de) | 2012-09-14 | 2013-09-13 | Neue, von d3 abgeleitete d-enantiomere peptide und deren verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2768264T3 true ES2768264T3 (es) | 2020-06-22 |
Family
ID=49354628
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13776426T Active ES2768264T3 (es) | 2012-09-14 | 2013-09-13 | Nuevos péptidos D-enantioméricos derivados de D3 y su uso |
| ES17172220T Active ES2938773T3 (es) | 2012-09-14 | 2013-09-13 | Nuevos péptidos D-enantioméricos derivados de D3 y su uso |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17172220T Active ES2938773T3 (es) | 2012-09-14 | 2013-09-13 | Nuevos péptidos D-enantioméricos derivados de D3 y su uso |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20150307552A1 (enExample) |
| EP (2) | EP2895867B1 (enExample) |
| JP (2) | JP6345670B2 (enExample) |
| CN (2) | CN107556375A (enExample) |
| DE (1) | DE102012108598A1 (enExample) |
| DK (2) | DK2895867T3 (enExample) |
| ES (2) | ES2768264T3 (enExample) |
| PL (1) | PL3346273T3 (enExample) |
| WO (1) | WO2014041115A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102012108598A1 (de) * | 2012-09-14 | 2014-04-10 | Forschungszentrum Jülich GmbH | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| DE102015003503A1 (de) * | 2015-03-20 | 2016-09-22 | Forschungszentrum Jülich GmbH | Spezifisch Amyloid-Beta bindende Peptide und deren Verwendung für die Therapie und Diagnose der Alzheimerschen Demenz |
| DE102015003676A1 (de) | 2015-03-20 | 2016-09-22 | Forschungszentrum Jülich GmbH Fachbereich Patente | Spezifisch A-Beta Spezies bindende Peptide für die Therapie und/oder die Diagnose der Alzheimerschen Demenz |
| DE102016125645A1 (de) * | 2016-12-23 | 2018-06-28 | Forschungszentrum Jülich GmbH | D-enantiomere Peptide zur Therapie von chronischem und neuropathischem Schmerz |
| WO2019070645A1 (en) * | 2017-10-02 | 2019-04-11 | Cedars-Sinai Medical Center | METHODS AND COMPOSITIONS FOR EFFECTIVE ADMINISTRATION THROUGH MULTIPLE BIOLOGICAL BARRIERS |
| DE102021121435A1 (de) * | 2021-08-18 | 2023-02-23 | Priavoid Gmbh | Aß-BINDENDE SUBSTANZEN |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE355374T1 (de) | 2000-11-27 | 2006-03-15 | Praecis Pharm Inc | Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen |
| WO2002081515A1 (fr) * | 2001-04-03 | 2002-10-17 | Kyowa Hakko Kogyo Co., Ltd. | Proteine de liaison de facteur de croissance de type insuline |
| DE10117281A1 (de) | 2001-04-06 | 2002-10-24 | Inst Molekulare Biotechnologie | Peptid zur Diagnose und Therapie der Alzheimer-Demenz |
| US20050158306A1 (en) * | 2004-01-16 | 2005-07-21 | Halikas James A. | Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| US20070092508A1 (en) * | 2005-10-21 | 2007-04-26 | Recombiant Technologies, Llc | Detoxification depot for Alzheimer's disease |
| US8445438B2 (en) | 2008-10-27 | 2013-05-21 | Recombinant Technologies Llc | Compositions comprising capture peptides for A β-amyloid peptide |
| DE102008037564A1 (de) * | 2008-11-19 | 2010-05-20 | Forschungszentrum Jülich GmbH | Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden |
| DE102010017130B4 (de) | 2010-05-28 | 2018-11-29 | Forschungszentrum Jülich GmbH | Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung |
| CN104380111B (zh) | 2012-04-05 | 2017-08-29 | 于利希研究中心有限公司 | 包含多价结合淀粉样β蛋白的D‑肽的聚合物及其应用 |
| DE102012108598A1 (de) * | 2012-09-14 | 2014-04-10 | Forschungszentrum Jülich GmbH | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| JP2015518474A (ja) * | 2012-04-05 | 2015-07-02 | フォルシュングスツェントルム ユーリッヒ ゲゼルシャフト ミット ベシュレンクテル ハフツングＦｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ Ｊｕｅｌｉｃｈ ＧｍｂＨ | 血液、血液生産物及び器官を処置する方法 |
-
2012
- 2012-09-14 DE DE102012108598.6A patent/DE102012108598A1/de not_active Withdrawn
-
2013
- 2013-09-13 CN CN201710944015.7A patent/CN107556375A/zh active Pending
- 2013-09-13 ES ES13776426T patent/ES2768264T3/es active Active
- 2013-09-13 PL PL17172220.0T patent/PL3346273T3/pl unknown
- 2013-09-13 EP EP13776426.2A patent/EP2895867B1/de active Active
- 2013-09-13 DK DK13776426.2T patent/DK2895867T3/da active
- 2013-09-13 DK DK17172220.0T patent/DK3346273T5/da active
- 2013-09-13 WO PCT/EP2013/068992 patent/WO2014041115A2/de not_active Ceased
- 2013-09-13 JP JP2015531567A patent/JP6345670B2/ja active Active
- 2013-09-13 ES ES17172220T patent/ES2938773T3/es active Active
- 2013-09-13 US US14/426,797 patent/US20150307552A1/en not_active Abandoned
- 2013-09-13 EP EP17172220.0A patent/EP3346273B1/de active Active
- 2013-09-13 CN CN201380047981.9A patent/CN104704371B/zh active Active
-
2017
- 2017-04-10 US US15/482,968 patent/US10167318B2/en not_active Expired - Fee Related
-
2018
- 2018-05-23 JP JP2018098517A patent/JP6611858B2/ja active Active
- 2018-11-27 US US16/200,820 patent/US10889618B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014041115A3 (de) | 2014-06-26 |
| EP3346273A1 (de) | 2018-07-11 |
| JP2015531348A (ja) | 2015-11-02 |
| JP6611858B2 (ja) | 2019-11-27 |
| PL3346273T3 (pl) | 2023-04-11 |
| CN104704371A (zh) | 2015-06-10 |
| ES2938773T3 (es) | 2023-04-14 |
| US20190085030A1 (en) | 2019-03-21 |
| DE102012108598A1 (de) | 2014-04-10 |
| EP3346273B1 (de) | 2023-01-04 |
| EP2895867A2 (de) | 2015-07-22 |
| US20170313744A1 (en) | 2017-11-02 |
| DK2895867T3 (da) | 2020-02-03 |
| JP6345670B2 (ja) | 2018-06-20 |
| CN107556375A (zh) | 2018-01-09 |
| EP3346273A8 (de) | 2018-08-29 |
| CN104704371B (zh) | 2017-11-07 |
| US10889618B2 (en) | 2021-01-12 |
| WO2014041115A2 (de) | 2014-03-20 |
| JP2018141008A (ja) | 2018-09-13 |
| DK3346273T3 (da) | 2023-02-27 |
| EP2895867B1 (de) | 2019-10-23 |
| US20150307552A1 (en) | 2015-10-29 |
| DK3346273T5 (da) | 2024-09-30 |
| US10167318B2 (en) | 2019-01-01 |
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