ES275601A1 - Un procedimiento para la fabricación de derivados de benzodiazepina - Google Patents

Un procedimiento para la fabricación de derivados de benzodiazepina

Info

Publication number
ES275601A1
ES275601A1 ES275601A ES275601A ES275601A1 ES 275601 A1 ES275601 A1 ES 275601A1 ES 275601 A ES275601 A ES 275601A ES 275601 A ES275601 A ES 275601A ES 275601 A1 ES275601 A1 ES 275601A1
Authority
ES
Spain
Prior art keywords
general formula
formula
see formula
manufacture
benzodiazepine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES275601A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US114038A external-priority patent/US3153082A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES275601A1 publication Critical patent/ES275601A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES275601A 1961-03-20 1962-03-17 Un procedimiento para la fabricación de derivados de benzodiazepina Expired ES275601A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9666361A 1961-03-20 1961-03-20
US114038A US3153082A (en) 1961-06-01 1961-06-01 2-amino-benzophenones

Publications (1)

Publication Number Publication Date
ES275601A1 true ES275601A1 (es) 1962-09-16

Family

ID=26791934

Family Applications (1)

Application Number Title Priority Date Filing Date
ES275601A Expired ES275601A1 (es) 1961-03-20 1962-03-17 Un procedimiento para la fabricación de derivados de benzodiazepina

Country Status (5)

Country Link
BE (1) BE615194A (de)
CH (2) CH459239A (de)
ES (1) ES275601A1 (de)
GB (2) GB985657A (de)
SE (1) SE301974B (de)

Also Published As

Publication number Publication date
GB985658A (en) 1965-03-10
DE1445858A1 (de) 1969-01-16
CH445500A (de) 1967-10-31
SE301974B (de) 1968-07-01
GB985657A (en) 1965-03-10
DE1445858B2 (de) 1975-07-03
CH459239A (de) 1968-07-15
BE615194A (fr) 1962-09-17

Similar Documents

Publication Publication Date Title
ES417638A1 (es) Procedimiento para preparar oxazoles 2,4,5-trisustituidos.
ES275601A1 (es) Un procedimiento para la fabricación de derivados de benzodiazepina
ES332579A1 (es) Un procedimiento para la preparacion de derivados de benzodiacepina.
ES311651A1 (es) Un procedimiento para la preparacion de derivados de quinazolina.
ES279296A1 (es) Un procedimiento para la fabricación de amidas
ES306429A1 (es) Un procedimiento para la preparacion de derivados de quinazolina.
GB972964A (en) A process for the manufacture of benzodiazepine derivatives
ES324458A1 (es) Un procedimiento para la preparacion de derivados de benzodiazepina.
ES278486A1 (es) Un procedimiento para la preparaciën de derivados de benzodiazepina
ES320299A1 (es) Un procedimiento para la preparacion de derivados de benzodiazepina.
ES285855A1 (es) Un procedimiento para la fabricación de derivados benzodiazepínicos
ES307526A1 (es) Un procedimiento para preparar derivados de benzodiazepina.
ES298318A1 (es) Procedimiento para la preparación de compuestos de quinazolona
ES330012A1 (es) Un procedimiento para la preparacion de compuestos de benzodiazepina.
ES455942A1 (es) Procedimiento para la preparacion de derivados de 2-fenil-2 hidroxietilamina.
ES347766A1 (es) Un procedimiento para preparar derivados de tetrazol.
ES335602A1 (es) Procedimiento para la obtencion de derivados del acido ditiocarbamidico.
ES305413A1 (es) Un procedimiento para la preparacion de derivados de benzodiazepina.
ES325546A1 (es) Procedimiento de preparacion de nuevos derivados biologicamente activos de la fenantridona.
ES276648A1 (es) Procedimiento para la fabricación de derivados de benzodiazepina
ES317706A1 (es) Un procedimiento para preparar derivados de benzodiazepina.
ES311604A1 (es) Un procedimiento para la preparacion de derivados de benzodiazepina.
ES317893A1 (es) Un procedimiento para la preparacion de derivados de benzodiazepina.
ES286241A1 (es) Un procedimiento para la fabricación de derivados benzodiazepínicos
ES295092A1 (es) Un procedimiento para la preparaciën de derivados de bencilamina y sus sales de adiciën de acido